4-Oxo-TEMPO - ≥95%(GC) , CAS No.2896-70-0

CAS: 2896-70-0 Cat. No.: O135821 Molecular Weight: 170.23 EC Number: 220-778-7 PubChem CID: 520789

GRADE & PURITY ≥95%(GC)

Synonyms

4-Oxo-2,2,6,6-tetramethylpiperidinyloxyl | 4-Oxo-tempo | O0266 | DTXSID4044905 | 4-oxo-2,2,6,6-tetramethylpiperidine-1-oxyl | Tempone | 4-Oxo-2,2,6,6-tetramethylpiperidine 1-oxyl, free radical | AKOS007930674 | Indium tin oxide coated PET, surface resisti

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

4-Oxo-TEMPO is formed by the reaction of 2,2,6,6-tetramethyl-4-piperidone (4-oxo-TMP) and 1O2. It is a stable paramagnetic product formed during the irradiation of TiO2 in aqueous suspensions.

Application：

4-Oxo-TEMPO was employed as nitroxide standard to investigate the generation of singlet oxygen by photoexcited TiO2 in ethanol by ESR spectroscopy. It may be employed as free radical polarizing agent in dynamic nuclear polarization (DNP) studies.

Free-radical nitroxide spin probe typically used for:

Redox sources for anodes in lithium secondary batteries

Free-radical biological studies

Radical spin-trapping

Electron paramagnetic resonance studies

Polymer chemisty and synthesis applications

Specifications

Synonyms

4-Oxo-2, 2, 6, 6-tetramethylpiperidinyloxyl | 4-Oxo-tempo | O0266 | DTXSID4044905 | 4-oxo-2, 2, 6, 6-tetramethylpiperidine-1-oxyl | Tempone | 4-Oxo-2, 2, 6, 6-tetramethylpiperidine 1-oxyl, free radical | AKOS007930674 | Indium tin oxide coated PET, surface resisti

Specifications & Purity

≥95%(GC)

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%(GC)

Names and Identifiers

• Pubchem Sid: 488190078
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488190078
• Isomeric SMILES: CC1(CC(=O)CC(N1[O])(C)C)C
• WGK Germany: 3
• RTECS: TN9200000
• PubChem CID: 520789
• Molecular Weight: 170.23
• Reaxy-Rn: 1818579

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (partly), acetone, DMSO, 100% ethanol, and diethylether. Insoluble in water.
• Sensitivity: Air & Heat Sensitive;Light sensitive
• Melt Point(°C): 39 °C
• Molecular Weight: 170.230 g/mol
• XLogP3: 0.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 170.118 Da
• Monoisotopic Mass: 170.118 Da
• Topological Polar Surface Area: 21.300 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 189.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Xiaoyan Chen, Jiangdong Cui, Xinyu Yang, Taoyue Yuan, Jiacheng Ge, Mengtao Ma, Shunke Ding, Wenhai Chu.  (2024)  Enhanced removal of phenolic contaminants with permanganate oxidation mediated by SiO2@TEMPO: Performance, transformation pathway, and selectivity.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.158210]

2. Xiuxiu Liu, Wenyu Chen, Minghao Sun, Xufang Lv, Xing Shen, Zhongping Chai, Maomao Zeng.  (2025)  The Effect of Cumin on the Formation of β-Carboline Heterocyclic Amines in Smoked Meat and Simulated Systems.  Foods,  14  (2): (299).  [PMID:39856964] [10.3390/foods14020299]

3. Yali Song, Ziyan Li, Cairong Yang, Xiaoyu Wen, Long Huang, Xiaojing Zhang, Yongpeng Ma, Qiong Wang, Hongzhong Zhang.  (2025)  Novel construction of Z–scheme g–C3N4/PDI organic photocatalyst for excellent sulfamethoxazole degradation rate in water.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.118371]