Ligands for E3 Ligase

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  1. 2-(2,6-Dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione
    CAS: 40313-92-6 Formula: C14H12N2O4 Molecular Weight: 272.26
    ◐ .Made to order · 8–12 wks Item #: D1238302
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    Technical Identifiers
    IUPAC Name
    2-(2,6-dioxopiperidin-3-yl)-5-methylisoindole-1,3-dione
    SMILES
    CC1=CC2=C(C=C1)C(=O)N(C2=O)C3CCC(=O)NC3=O
    InChIKey
    FIRKPGPRAMCBHV-UHFFFAOYSA-N
    InChI
    1S/C14H12N2O4/c1-7-2-3-8-9(6-7)14(20)16(13(8)19)10-4-5-11(17)15-12(10)18/h2-3,6,10H,4-5H2,1H3,(H,15,17,18)
  2. (4R,5S)-Nutlin carboxylic acid
    CAS: 2306390-08-7 PubChem CID: 138911380
    ◐ .Made to order · 8–12 wks Item #: R1449802
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    Technical Identifiers
    IUPAC Name
    2-[4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]acetic acid
    SMILES
    CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCN(C(=O)C3)CC(=O)O)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
    InChIKey
    CYFZSMNCDNFMOG-IHLOFXLRSA-N
    InChI
    1S/C32H32Cl2N4O6/c1-19(2)44-26-16-24(43-3)12-13-25(26)31-35-29(20-4-8-22(33)9-5-20)30(21-6-10-23(34)11-7-21)38(31)32(42)37-15-14-36(18-28(40)41)27(39)show more
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Frequently Asked Questions

How do I choose the right Ligands for E3 Ligase for my conjugate design?
Work from both ends inward: the reactive handle that has to couple to your payload or protein, and the linker length or ternary-complex geometry the design needs, then match a Ligands for E3 Ligase entry to both. Solubility and stability under conjugation and storage conditions decide whether a design survives scale-up.
What does Ligands for E3 Ligase cover?
Ligands for E3 Ligase is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
What specifications matter most for Ligands for E3 Ligase?
For Ligands for E3 Ligase, check purity by HPLC, identity by MS, the reactive group and its protection state, linker length or PEG polydispersity, and solubility in your conjugation solvent. Moisture-sensitive handles need controlled storage and prompt use after opening. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Ligands for E3 Ligase I need is not listed?
Search Ligands for E3 Ligase by SMILES first, since close analogs are often listed under a neighbouring subcategory. Custom synthesis enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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