Epigenetics

Explore pathway-focused compounds for epigenetics research, including tools relevant to chromatin regulation and transcriptional control. Use this page to compare molecules used in target validation, mechanism studies, and cell-state modulation workflows.

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  1. GSK J5 HCl
    CAS: 1797983-32-4 PubChem CID: 126456082 Formula: C₂₄H₂₇N₅O₂•HCl Molecular Weight: 453.97
    ◐ .Made to order · 8–12 wks Item #: G288263
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    IUPAC Name
    ethyl 3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate;hydrochloride
    SMILES
    CCOC(=O)CCNC1=CC(=NC(=N1)C2=CN=CC=C2)N3CCC4=CC=CC=C4CC3.Cl
    InChIKey
    QQHQMHJAOKADED-UHFFFAOYSA-N
    InChI
    1S/C24H27N5O2.ClH/c1-2-31-23(30)9-13-26-21-16-22(28-24(27-21)20-8-5-12-25-17-20)29-14-10-18-6-3-4-7-19(18)11-15-29;/h3-8,12,16-17H,2,9-11,13-15H2,1H3,show more
    Synonyms
    N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride
  2. PFI 4, bromodomain and PHD finger containing 1
    CAS: 900305-37-5 PubChem CID: 40642506 Formula: C21H24N4O3 Molecular Weight: 380.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US Item #: P287481
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    IUPAC Name
    N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide
    SMILES
    CN1C2=C(C=C(C(=C2)NC(=O)C3=CC=CC=C3OC)N4CCCC4)N(C1=O)C
    InChIKey
    QCIJLRJBZDBVDB-UHFFFAOYSA-N
    InChI
    1S/C21H24N4O3/c1-23-17-12-15(22-20(26)14-8-4-5-9-19(14)28-3)16(25-10-6-7-11-25)13-18(17)24(2)21(23)27/h4-5,8-9,12-13H,6-7,10-11H2,1-3H3,(H,22,26)
    Synonyms
    N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide
  3. Lumbrokinase
    CAS: 556743-18-1
    EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. ≥12000U/mg
    ● In Stock — US Item #: L115121
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    Bioactivity
    ≥12000U/mg
  4. GSK690693, Protein kinase C (PKC) inhibitor
    CAS: 937174-76-0 EC Number: 804-554-1 Formula: C21H27N7O3 Molecular Weight: 425.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US Item #: G127527
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    IUPAC Name
    4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[[(3S)-piperidin-3-yl]methoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
    SMILES
    CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
    InChIKey
    KGPGFQWBCSZGEL-ZDUSSCGKSA-N
    InChI
    1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,2show more
    Synonyms
    (R)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-yl-MeO)-1H-imidazo[4,5-c]pyridin-4-yl)-2-Me-but-3-yn-2...
  5. NCH 51
    CAS: 848354-66-5 Formula: C20H26N2O2S2 Molecular Weight: 390.57
    ● In Stock — US Item #: N274711
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    IUPAC Name
    S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate
    SMILES
    CC(C)C(=O)SCCCCCCC(=O)NC1=NC(=CS1)C2=CC=CC=C2
    InChIKey
    MDYDGUOQFUQOGE-UHFFFAOYSA-N
    InChI
    1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)
    Synonyms
    S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate | dibenzo[b,d]furan-4-yl boronic acid | N...
  6. GSK503
    CAS: 1346572-63-1 Formula: C31H38N6O2 Molecular Weight: 526.67
    ● In Stock — US Item #: G276508
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    IUPAC Name
    N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-methyl-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindole-4-carboxamide
    SMILES
    CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C(=CN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C)C
    InChIKey
    HRDQQHUKUIKFHT-UHFFFAOYSA-N
    InChI
    1S/C31H38N6O2/c1-19(2)37-18-21(4)29-25(30(38)33-17-26-20(3)13-22(5)34-31(26)39)14-24(15-27(29)37)23-7-8-28(32-16-23)36-11-9-35(6)10-12-36/h7-8,13-16,1show more
    Synonyms
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyr...
  7. GSK484 hydrochloride
    CAS: 1652591-81-5 Formula: C27H32ClN5O3 Molecular Weight: 510.03
    ● In Stock — US Item #: G276185
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    IUPAC Name
    [(3S,4R)-3-amino-4-hydroxypiperidin-1-yl]-[2-[1-(cyclopropylmethyl)indol-2-yl]-7-methoxy-1-methylbenzimidazol-5-yl]methanone;hydrochloride
    SMILES
    CN1C2=C(C=C(C=C2OC)C(=O)N3CCC(C(C3)N)O)N=C1C4=CC5=CC=CC=C5N4CC6CC6.Cl
    InChIKey
    MULKOGJHUZTANI-ADMBKAPUSA-N
    InChI
    1S/C27H31N5O3.ClH/c1-30-25-20(11-18(13-24(25)35-2)27(34)31-10-9-23(33)19(28)15-31)29-26(30)22-12-17-5-3-4-6-21(17)32(22)14-16-7-8-16;/h3-6,11-13,16,19show more
    Synonyms
    Pharmakon1600-01500687 | [(3S,4R)-3-amino-4-hydroxypiperidin-1-yl]-[2-[1-(cyclopropylmethyl)indol-2-yl]-7-methoxy-1-m...
  8. GSK6853
    CAS: 1910124-24-1 Formula: C22H27N5O3 Molecular Weight: 409.48
    ● In Stock — US Item #: G275395
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    IUPAC Name
    N-[1,3-dimethyl-6-[(2R)-2-methylpiperazin-1-yl]-2-oxobenzimidazol-5-yl]-2-methoxybenzamide
    SMILES
    CC1CNCCN1C2=CC3=C(C=C2NC(=O)C4=CC=CC=C4OC)N(C(=O)N3C)C
    InChIKey
    FQWDVNSBYDXPIO-CQSZACIVSA-N
    InChI
    1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28show more
    Synonyms
    N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxybenzamide | (R)-N-(1...
  9. GSK-LSD1 Dihydrochloride
    CAS: 2102933-95-7 PubChem CID: 91663353 Formula: C14H22Cl2N2 Molecular Weight: 289.24
    ◐ .Made to order · 8–12 wks Item #: G302771
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    IUPAC Name
    N-[(1R,2S)-2-phenylcyclopropyl]piperidin-4-amine;dihydrochloride
    SMILES
    C1CNCCC1NC2CC2C3=CC=CC=C3.Cl.Cl
    InChIKey
    PJFZOGMSPBHPNS-WICJZZOFSA-N
    InChI
    1S/C14H20N2.2ClH/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12;;/h1-5,12-16H,6-10H2;2*1H/t13-,14+;;/m0../s1
    Synonyms
    GSK LSD 1 dihydrochloriderel-N-[(1S,2R)-2-Phenylcyclopropyl]-4-piperidinamine dihydrochloride
  10. Bisindolylmaleimide X hydrochloride (Ro 31-8425)
    CAS: 145317-11-9 Formula: C26H25ClN4O2 Molecular Weight: 460.96
    ◐ .Made to order · 8–12 wks Item #: B275168
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    IUPAC Name
    3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione;hydrochloride
    SMILES
    CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN.Cl
    InChIKey
    IMBOYWXMTUUYGZ-UHFFFAOYSA-N
    InChI
    1S/C26H24N4O2.ClH/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30;/h2-9,14-15H,10-13,27H2,1Hshow more
    Synonyms
    3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dionehydrochloride
  11. PCI-24781 (Abexinostat), Histone deacetylase inhibitor
    CAS: 783355-60-2 Formula: C21H23N3O5 Molecular Weight: 397.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US Item #: P126975
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    IUPAC Name
    3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
    SMILES
    CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
    InChIKey
    MAUCONCHVWBMHK-UHFFFAOYSA-N
    InChI
    1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
    Synonyms
    DB12565 | BDBM24622 | ABEXINOSTAT [WHO-DD] | AKOS025149423 | FT-0673532 | UDWXLZLRRVQONG-UHFFFAOYSA-M | CRA-02478 | A...
  12. Bisindolylmaleimide III
    CAS: 137592-43-9 Formula: C23H20N4O2 Molecular Weight: 384.43
    ● In Stock — US Item #: B276080
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    Technical Identifiers
    IUPAC Name
    3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
    SMILES
    C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCN
    InChIKey
    APYXQTXFRIDSGE-UHFFFAOYSA-N
    InChI
    1S/C23H20N4O2/c24-10-5-11-27-13-17(15-7-2-4-9-19(15)27)21-20(22(28)26-23(21)29)16-12-25-18-8-3-1-6-14(16)18/h1-4,6-9,12-13,25H,5,10-11,24H2,(H,26,28,2show more
    Synonyms
    3-[1-(3-Aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
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Frequently Asked Questions

What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which Epigenetics subcategory should I start with?
Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering Epigenetics?
Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Epigenetics by structure or CAS number?
Yes. Within Epigenetics you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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