Epigenetic Reader Domain

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  1. PFI 4, bromodomain and PHD finger containing 1
    CAS: 900305-37-5 PubChem CID: 40642506 Formula: C21H24N4O3 Molecular Weight: 380.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US Item #: P287481
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    IUPAC Name
    N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide
    SMILES
    CN1C2=C(C=C(C(=C2)NC(=O)C3=CC=CC=C3OC)N4CCCC4)N(C1=O)C
    InChIKey
    QCIJLRJBZDBVDB-UHFFFAOYSA-N
    InChI
    1S/C21H24N4O3/c1-23-17-12-15(22-20(26)14-8-4-5-9-19(14)28-3)16(25-10-6-7-11-25)13-18(17)24(2)21(23)27/h4-5,8-9,12-13H,6-7,10-11H2,1-3H3,(H,22,26)
    Synonyms
    N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide
  2. GSK6853
    CAS: 1910124-24-1 Formula: C22H27N5O3 Molecular Weight: 409.48
    ● In Stock — US Item #: G275395
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    IUPAC Name
    N-[1,3-dimethyl-6-[(2R)-2-methylpiperazin-1-yl]-2-oxobenzimidazol-5-yl]-2-methoxybenzamide
    SMILES
    CC1CNCCN1C2=CC3=C(C=C2NC(=O)C4=CC=CC=C4OC)N(C(=O)N3C)C
    InChIKey
    FQWDVNSBYDXPIO-CQSZACIVSA-N
    InChI
    1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28show more
    Synonyms
    N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxybenzamide | (R)-N-(1...
  3. SGC-CBP30, Inhibitor of CREB binding protein;Inhibitor of E1A binding protein p300
    CAS: 1613695-14-9 EC Number: 106-820-6 PubChem CID: 72201027 Formula: C28H33ClN4O3 Molecular Weight: 509.04
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US Item #: S357869
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    IUPAC Name
    4-[(2S)-1-[2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]propan-2-yl]morpholine
    SMILES
    CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC(=C(C=C4)OC)Cl)CC(C)N5CCOCC5
    InChIKey
    GEPYBHCJBORHCE-SFHVURJKSA-N
    InChI
    1S/C28H33ClN4O3/c1-18(32-11-13-35-14-12-32)17-33-25-8-7-22(28-19(2)31-36-20(28)3)16-24(25)30-27(33)10-6-21-5-9-26(34-4)23(29)15-21/h5,7-9,15-16,18H,6,show more
  4. OF 1, bromodomain and PHD finger containing 1;bromodomain and PHD finger containing 3
    CAS: 919973-83-4 EC Number: 809-510-5 Formula: C17H18BrN3O4S Molecular Weight: 440.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US Item #: O286836
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    IUPAC Name
    4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxobenzimidazol-5-yl)-2-methylbenzenesulfonamide
    SMILES
    CC1=C(C=CC(=C1)Br)S(=O)(=O)NC2=CC3=C(C=C2OC)N(C(=O)N3C)C
    InChIKey
    YUNQZQREIHWDQT-UHFFFAOYSA-N
    InChI
    1S/C17H18BrN3O4S/c1-10-7-11(18)5-6-16(10)26(23,24)19-12-8-13-14(9-15(12)25-4)21(3)17(22)20(13)2/h5-9,19H,1-4H3
    Synonyms
    OF-1, >=98% (HPLC) | 9,10-Anthraguinone | AKOS000481248 | EX-A2269 | A16000 | NCGC00384195-05 | GTPL9523 | 4-bromo-N-...
  5. OTX015, Bromodomain and extra-terminal motif (BET) inhibitor
    CAS: 202590-98-5 Formula: C25H22ClN5O2S Molecular Weight: 491.99
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US Item #: O125058
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    IUPAC Name
    2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]-N-(4-hydroxyphenyl)acetamshow more
    SMILES
    CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C
    InChIKey
    GNMUEVRJHCWKTO-FQEVSTJZSA-N
    InChI
    1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,show more
    Synonyms
    OTX 015 | OTX-015 | 2-((6S)-4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-6H-THIENO(3,2- F)(1,2,4)TRIAZOLO(4,3-A)(1,4)DIAZEPIN-6...
  6. CPI203, Inhibitor of bromodomain containing 4
    CAS: 1446144-04-2 Formula: C19H18ClN5OS Molecular Weight: 399.9
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US Item #: C167316
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    IUPAC Name
    2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetamide
    SMILES
    CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)N)C4=CC=C(C=C4)Cl)C
    InChIKey
    QECMENZMDBOLDR-AWEZNQCLSA-N
    InChI
    1S/C19H18ClN5OS/c1-9-10(2)27-19-16(9)17(12-4-6-13(20)7-5-12)22-14(8-15(21)26)18-24-23-11(3)25(18)19/h4-7,14H,8H2,1-3H3,(H2,21,26)/t14-/m0/s1
    Synonyms
    (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
  7. BI 2536, Serine/threonine-protein kinase PLK1 inhibitor
    CAS: 755038-02-9 EC Number: 999-050-2 Formula: C28H39N7O3 Molecular Weight: 521.66
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US Item #: B129994
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    IUPAC Name
    4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
    SMILES
    CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
    InChIKey
    XQVVPGYIWAGRNI-JOCHJYFZSA-N
    InChI
    1S/C28H39N7O3/c1-5-22-27(37)34(3)23-17-29-28(32-25(23)35(22)20-8-6-7-9-20)31-21-11-10-18(16-24(21)38-4)26(36)30-19-12-14-33(2)15-13-19/h10-11,16-17,19show more
    Synonyms
    (R)-4-(8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)-3-methoxy-N-(1-methylpiperidin-4-yl...
  8. OXF BD 02
    CAS: 1429129-68-9 Formula: C18H17NO3 Molecular Weight: 295.33
    ● In Stock — US Item #: O287867
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    IUPAC Name
    3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[hydroxy(phenyl)methyl]phenol
    SMILES
    CC1=C(C(=NO1)C)C2=CC(=CC(=C2)O)C(C3=CC=CC=C3)O
    InChIKey
    FEQUIPXIENTMJN-UHFFFAOYSA-N
    InChI
    1S/C18H17NO3/c1-11-17(12(2)22-19-11)14-8-15(10-16(20)9-14)18(21)13-6-4-3-5-7-13/h3-10,18,20-21H,1-2H3
    Synonyms
    3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenylbenzenemethanol
  9. PF CBP1
    CAS: 1962928-21-7 PubChem CID: 119081417 Formula: C29H36N4O3 Molecular Weight: 488.62
    ● In Stock — US Item #: P288278
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    IUPAC Name
    4-[2-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[2-(4-propoxyphenyl)ethyl]benzimidazol-1-yl]ethyl]morpholine
    SMILES
    CCCOC1=CC=C(C=C1)CCC2=NC3=C(N2CCN4CCOCC4)C=CC(=C3)C5=C(ON=C5C)C
    InChIKey
    CGWBJJZOKGZCSJ-UHFFFAOYSA-N
    InChI
    1S/C29H36N4O3/c1-4-17-35-25-9-5-23(6-10-25)7-12-28-30-26-20-24(29-21(2)31-36-22(29)3)8-11-27(26)33(28)14-13-32-15-18-34-19-16-32/h5-6,8-11,20H,4,7,12-show more
    Synonyms
    5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole
  10. I-BET 151 dihydrochloride
    CAS: 1883545-47-8 PubChem CID: 121513850 Formula: C23H21N5O3•2HCl Molecular Weight: 488.37
    ● In Stock — US Item #: I287715
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    Technical Identifiers
    IUPAC Name
    7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one;dihydrochloride
    SMILES
    CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)C(C)C5=CC=CC=N5)OC.Cl.Cl
    InChIKey
    UFLKDZBLUNJNJS-FFXKMJQXSA-N
    InChI
    1S/C23H21N5O3.2ClH/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17;;/h5-11,13H,1-4H3,(H,26,29);2*1show more
    Synonyms
    I-BET151 dihydrochloride | GSK1210151A dihydrochloride | 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R...
  11. I-BET151, Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4
    CAS: 1300031-49-5 EC Number: 802-803-9 Formula: C23H21N5O3 Molecular Weight: 415.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US Item #: I124882
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    Technical Identifiers
    IUPAC Name
    7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one
    SMILES
    CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)C(C)C5=CC=CC=N5)OC
    InChIKey
    VUVUVNZRUGEAHB-CYBMUJFWSA-N
    InChI
    1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1
    Synonyms
    BDBM50380682 | GTPL7518 | 1GH | DTXSID10680599 | 2H-Imidazo[4,5-c]quinolin-2-one, 7-(3,5-dimethyl-4-isoxazolyl)-1,3-d...
  12. I-BRD9, Inhibitor of bromodomain containing 9
    CAS: 1714146-59-4 Formula: C22H22F3N3O3S2 Molecular Weight: 497.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US Item #: I287753
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    IUPAC Name
    N'-(1,1-dioxothian-4-yl)-5-ethyl-4-oxo-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
    SMILES
    CCN1C=C(C2=C(C1=O)C=C(S2)C(=NC3CCS(=O)(=O)CC3)N)C4=CC(=CC=C4)C(F)(F)F
    InChIKey
    WRUWGLUCNBMGPS-UHFFFAOYSA-N
    InChI
    1S/C22H22F3N3O3S2/c1-2-28-12-17(13-4-3-5-14(10-13)22(23,24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30,31)9-7-15/h3-5,10-12,15H,2,6-9H2,1H3,(Hshow more
    Synonyms
    5-Ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyri...
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Frequently Asked Questions

Which compounds are listed for Epigenetic Reader Domain?
Compounds associated with Epigenetic Reader Domain are grouped here under the Epigenetics classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Epigenetic Reader Domain sit within Epigenetics?
Epigenetic Reader Domain is one target listing within the Epigenetics classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Epigenetic Reader Domain?
For compounds listed under Epigenetic Reader Domain, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Epigenetic Reader Domain?
Browse the parent Epigenetics listing to reach targets neighbouring Epigenetic Reader Domain, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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