4,4′-Dimethoxytrityl chloride（DMT-Cl） - ≥97% , CAS No.40615-36-9

CAS: 40615-36-9 Cat. No.: D109292 Molecular Weight: 338.83 Beilstein Registry Number: 2471942 EC Number: 255-002-6

GRADE & PURITY ≥97%

Synonyms

4,4'-Dimethoxytrityl chloride | 1,1'-(Chlorophenylmethylene)bis(4-methoxybenzene) | 4,4'-dimethoxytritylchloride | 4,4'-Dimethoxy-tritylchloride | BCP17241 | Benzene, 1,1'-(chlorophenylmethylene)bis(4-methoxy- | 4,4'-Dimethoxy-triphenylchlormethane | AC-7

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Hydroxyl Protecting Agent

Specifications

Synonyms

4, 4'-Dimethoxytrityl chloride | 1, 1'-(Chlorophenylmethylene)bis(4-methoxybenzene) | 4, 4'-dimethoxytritylchloride | 4, 4'-Dimethoxy-tritylchloride | BCP17241 | Benzene, 1, 1'-(chlorophenylmethylene)bis(4-methoxy- | 4, 4'-Dimethoxy-triphenylchlormethane | AC-7

Specifications & Purity

≥97%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 508809149
• Canonical Smiles: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)Cl
• IUPAC Name: 1-[chloro-(4-methoxyphenyl)-phenylmethyl]-4-methoxybenzene
• InChIKey: JBWYRBLDOOOJEU-UHFFFAOYSA-N
• INCHI: 1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
• Isomeric SMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)Cl
• WGK Germany: 3
• Molecular Weight: 338.83
• Beilstein: 2471942
• Reaxy-Rn: 2471942
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2471942&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Triphenyl compounds

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Triphenyl compounds
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Triphenyl compounds
• Alternative Parents: Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Organochlorides Hydrocarbon derivatives Alkyl chlorides
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Triphenyl compound - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - Ether - Organic oxygen compound - Organohalogen compound - Organochloride - Organooxygen compound - Hydrocarbon derivative - Alkyl halide - Alkyl chloride - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in chloroform and methanol. Partially soluble in water
• Sensitivity: Moisture sensitive
• Melt Point(°C): 119-125°C
• Molecular Weight: 338.800 g/mol
• XLogP3: 5.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 338.107 Da
• Monoisotopic Mass: 338.107 Da
• Topological Polar Surface Area: 18.500 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 340.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Qingxue Li, Danqi Li, Bo Zhuang, Wenkai Zhang, Ran-Ran Feng, Feng Gai.  (2025)  Photophysics of a Nucleoside Analogue: 4-Cyanoindole-2′-deoxyribonucleoside.  JOURNAL OF PHYSICAL CHEMISTRY B,      [PMID:40047380] [10.1021/acs.jpcb.5c00508]