Cevimeline hydrochloride , CAS No.107220-28-0

CAS: 107220-28-0 Cat. No.: C287826 Summenformel: C₁₀H₁₇NOS•HCl Molekulargewicht: 235.77 EG-Nummer: 689-009-4

Synonyms

Cevimeline hydrochloride | AKOS030526237 | (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrochloride | Evoxac | DTXSID10891421 | HY-70020B | AF-102B hydrochloride | AKOS025311302 | MS-23364 | Cevimeline,hydrochloride salt | 14281

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyme

Cevimeline hydrochloride | AKOS030526237 | (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrochloride | Evoxac | DTXSID10891421 | HY-70020B | AF-102B hydrochloride | AKOS025311302 | MS-23364 | Cevimeline,hydrochloride salt | 14281

Biochemische und physiologische Mechanismen

Selective M1receptor agonist. Induces atropine-sensitive contractions of isolated guinea pig ilea and trachea preparations (EC50values are 3.5 and 3μM respectively). Reverses AF64A-induced cognitive impairmentsin vivo.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

• Kanonisches Lächeln: CC1OC2(CN3CCC2CC3)CS1.Cl
• IUPAC Name: (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrochloride
• InChIKey: SURWTGAXEIEOGY-GHXDPTCOSA-N
• INCHI: 1S/C10H17NOS.ClH/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;/h8-9H,2-7H2,1H3;1H/t8-,10-;/m1./s1
• Isomere SMILES: C[C@@H]1O[C@]2(CN3CCC2CC3)CS1.Cl
• Molekulargewicht: 235.77
• Reaxy-Rn: 14659663
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14659663&ln=

Chemische und physikalische Eigenschaften

• Löslichkeit: Solvent:water, Max Conc. mg/mL: 17.68, Max Conc. mM: 75; Solvent:DMSO, Max Conc. mg/mL: 11.79, Max Conc. mM: 50
• Molekulargewicht: 235.770 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 235.08 Da
• Monoisotopic Mass: 235.08 Da
• Topological Polar Surface Area: 37.800 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 215.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Häufig gestellte Fragen

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 107220-28-0, the molecular formula is C10H18ClNOS, and the molecular weight is 235.77 g/mol. InChIKey SURWTGAXEIEOGY-GHXDPTCOSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.