Cycloheximide (NSC-185) - Moligand™, 10mM in DMSO , 80S Ribosome inhibitor, CAS No.66-81-9, 80S Ribosome inhibitor

CAS: 66-81-9 Cat. No.: C408230 Summenformel: C₁₅H₂₃NO₄ Molekulargewicht: 281.35 EG-Nummer: 200-636-0

QUALITÄT & REINHEIT Moligand™, 10mM in DMSO

Synonyms

Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80 | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs,FedEx DG Service

Übersicht

Information

Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo,
In vitro

In vivo

Cell Data

cell lines：HT29, Colo205, PC-3, MDA-MB-231 and K562 cells

Concentrations：

Incubation Time：

Powder Purity:≥97%

Spezifikationen

Synonyme

Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80 | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Spezifikationen & Reinheit

Moligand™, 10mM in DMSO

Biochemische und physiologische Mechanismen

Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximid

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs,FedEx DG Service

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Mechanismus der Wirkung

80S Ribosome inhibitor

Produkteigenschaften

ALogP

0.5

Namen und Kennungen

Isomere SMILES

C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C

UN-Nummer

2811

Verpackungsgruppe

II

Molekulargewicht

281.35

Reaxy-Rn

9515475

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9515475&ln=

Zugehörige Ziele (menschlich)

EIF4A1 Tchem Eukaryotic initiation factor 4A-I (0 Activities)

Discover Target: EIF4A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (0 Activities)

Discover Target: SLC2A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 53 mg/mL (79.62 mM); Water: Insoluble; Ethanol: Insoluble
• Flammpunkt (°F): 230°F
• Flammpunkt (°C): >110°C
• Siedepunkt (°C): 492°C
• Schmelzpunkt (°C): 119.5-121°C

Häufig gestellte Fragen

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 66-81-9, the molecular formula is C15H23NO4, and the molecular weight is 281.35 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.