Echinatin - ≥98% , CAS No.34221-41-5

CAS: 34221-41-5 Cat. No.: E418602 Summenformel: C16H14O4 Molekulargewicht: 270.28
Zu bestellen verfügbar
GRADE & PURITY ≥98%
Synonyms
(E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-phenyl)-propenone | HY-N0269 | A875066 | DTXSID301019928 | (E)-3-(4-hydroxy-2-methoxy-phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | s9437
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Deutschland (EU)
USA*
Price
Qty
5mg
E418602-5mg
—
3 Auf Lager

82,35€

108,38€
Speichern 26,03 € (24.02%)
10mg
E418602-10mg
—
2 Auf Lager

124,00€

145,69€
Speichern 21,69 € (14.89%)
25mg
E418602-25mg
—
1 Auf Lager

233,34€

273,25€
Speichern 39,92 € (14.61%)
50mg
E418602-50mg
—
1 Auf Lager

334,86€

434,65€
Speichern 99,79 € (22.96%)
100mg
E418602-100mg
—
1 Auf Lager

595,18€

694,97€
Speichern 99,79 € (14.36%)
200mg
E418602-200mg
—
1 Auf Lager

991,74€

1.158,34€
Speichern 166,61 € (14.38%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Echinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.

Specifications

Synonyme
(E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-phenyl)-propenone | HY-N0269 | A875066 | DTXSID301019928 | (E)-3-(4-hydroxy-2-methoxy-phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | s9437
Spezifikationen & Reinheit
≥98%
Storage
Protected from light,Store at -20°C
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Reinheit
≥98%
Produkteigenschaften
ALogP3.201
hba_count2
HBD-Zahl2
Rotationsfähige Bindung4
Namen und Kennungen
Pubchem Sid488195796
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195796
Kanonisches LächelnCOC1=C(C=CC(=C1)O)C=CC(=O)C2=CC=C(C=C2)O
IUPAC Name(E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
InChIKeyQJKMIJNRNRLQSS-WEVVVXLNSA-N
INCHI1S/C16H14O4/c1-20-16-10-14(18)8-4-12(16)5-9-15(19)11-2-6-13(17)7-3-11/h2-10,17-18H,1H3/b9-5+
Isomere SMILES COC1=C(C=CC(=C1)O)/C=C/C(=O)C2=CC=C(C=C2)O
Molekulargewicht 270.28
Reaxy-Rn 2135981
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2135981&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
KlasseLinear 1,3-diarylpropanoids
SubclassChalcones and dihydrochalcones
Intermediate Tree Nodes Not available
Direct ParentRetrochalcones
Alternative Parents Cinnamylphenols  Hydroxycinnamic acids and derivatives  Methoxyphenols  Styrenes  Phenoxy compounds  Methoxybenzenes  Benzoyl derivatives  Aryl ketones  Anisoles  Alkyl aryl ethers  1-hydroxy-2-unsubstituted benzenoids  Enones  Acryloyl compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Retrochalcone - Cinnamylphenol - Hydroxycinnamic acid or derivatives - Methoxyphenol - Phenoxy compound - Anisole - Methoxybenzene - Benzoyl - Aryl ketone - Styrene - Phenol ether - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Phenol - Monocyclic benzene moiety - Benzenoid - Acryloyl-group - Alpha,beta-unsaturated ketone - Enone - Ketone - Ether - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
BeschreibungThis compound belongs to the class of organic compounds known as retrochalcones. These are a form of normal chalcones that are structurally distinguished by the lack of oxygen functionalities at the C2'- and C6'-positions.
External Descriptors Chalcones and dihydrochalcones
3D-Struktur
Interaktives chemisches Strukturmodell





Zugehörige Ziele (menschlich)
TOP1 Tclin DNA topoisomerase I (7553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSB Tchem Cathepsin B (3822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNU-638 (372 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SW480 (6023 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
T47D (39041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Zugehörige Ziele (nicht menschlich)
NA Neuraminidase (1107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSL Cathepsin L (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Influenza A virus (11224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nanH Sialidase (337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDatumArtikel
D2301288Certificate of AnalysisFeb 04, 2023 E418602
K2405014Certificate of AnalysisFeb 04, 2023 E418602
H2416018Certificate of AnalysisFeb 04, 2023 E418602
D2301318Certificate of AnalysisFeb 04, 2023 E418602
D2301317Certificate of AnalysisFeb 04, 2023 E418602
D2301314Certificate of AnalysisFeb 04, 2023 E418602
D2301300Certificate of AnalysisFeb 04, 2023 E418602
D2301297Certificate of AnalysisFeb 04, 2023 E418602
D2301296Certificate of AnalysisFeb 04, 2023 E418602
B2422027Certificate of AnalysisFeb 04, 2023 E418602
D2301284Certificate of AnalysisFeb 04, 2023 E418602
D2301276Certificate of AnalysisFeb 04, 2023 E418602
D2301274Certificate of AnalysisFeb 04, 2023 E418602
D2301267Certificate of AnalysisFeb 04, 2023 E418602
D2301257Certificate of AnalysisFeb 04, 2023 E418602
C2508145Certificate of AnalysisFeb 04, 2023 E418602
B2429014Certificate of AnalysisFeb 04, 2023 E418602

Show more ⌵

Chemische und physikalische Eigenschaften
EmpfindlichkeitLight sensitive
DMSO (mg/ml) Maximale Löslichkeit54
DMSO (mM) Maximale Löslichkeit199.792837027207
Molekulargewicht270.280 g/mol
XLogP33.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass270.089 Da
Monoisotopic Mass270.089 Da
Topological Polar Surface Area66.800 Ų
Heavy Atom Count20
Formal Charge0
Complexity344.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
FAQs und Artikel
Lösungsrechner
Bewertungen

Kundenbewertungen

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.