1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane: Properties & Lab Guide

1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane is a partially fluorinated ether compound belonging to the hydrofluoroether (HFE) family, valued in research for its chemical inertness, low toxicity relative to perfluorocarbons, non-flammability, and excellent solvating properties toward fluorinated materials.

Chemical Name

1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane

SKU

N1320598

Chemical Class

Hydrofluoroether (HFE); partially fluorinated aliphatic ether

Key Physical Property

Non-flammable liquid with low surface tension, characteristic of fluorinated ethers

Primary Research Uses

Fluorinated solvent, carrier fluid for fluorinated compounds, surface treatment studies, specialty synthesis

Supplier

Aladdin Scientific

Chemical Identity and Structure

1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane (SKU: N1320598) is a hydrofluoroether (HFE) in which nine fluorine atoms are positioned on a four-carbon perfluoroalkyl segment, while a propoxy group provides the ether linkage on the hydrocarbon side. This asymmetric architecture—combining a perfluorinated tail with a hydrocarbon ether segment—is the defining structural feature of the HFE class.

The molecular formula can be represented as C₉H₉F₉O, reflecting the balance between fluorinated and non-fluorinated carbon centers. The presence of both fluorinated and non-fluorinated domains imparts an amphiphilic character that distinguishes HFEs from fully fluorinated perfluorocarbons (PFCs), giving them improved miscibility with common organic solvents while retaining many desirable fluorinated-material properties.

Physicochemical Properties and Stability

As a member of the HFE family, 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane is expected to exhibit the following physicochemical characteristics typical of its class:

• Appearance: Clear, colorless liquid under standard conditions.
• Flammability: Non-flammable, a critical safety advantage over conventional hydrocarbon solvents.
• Surface Tension: Low surface tension, enabling excellent wetting of surfaces—valuable in cleaning, coating, and deposition applications.
• Thermal Stability: High thermal and chemical stability due to the strong C–F bonds in the perfluoroalkyl segment.
• Vapor Pressure: Moderate vapor pressure typical of liquid HFEs; consult the Safety Data Sheet (SDS) for precise values.
• Miscibility: Partially miscible with common organic solvents; limited miscibility with water, consistent with its fluorinated character.

Note: Specific numerical values for boiling point, density, viscosity, and vapor pressure should be confirmed against the product SDS or certificate of analysis (CoA) provided by Aladdin Scientific, as precise figures were not included in the available source material.

Research Applications

Hydrofluoroethers such as 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane find application across multiple research domains:

1. Fluorinated Solvent Systems: Used as a solvent or co-solvent for dissolving fluorinated polymers, fluorinated surfactants, and other fluorophilic compounds that are poorly soluble in conventional organic media.
2. Precision Cleaning: HFEs are established precision cleaning agents for delicate electronic components and optical assemblies due to their non-flammability and low surface tension.
3. Surface Treatment Research: Employed as carrier fluids for fluorinated surface-treatment agents in studies of hydrophobic and oleophobic coatings.
4. Specialty Synthesis: Can serve as a reaction medium for fluorine chemistry where an inert, fluorophilic solvent environment is required.
5. Heat Transfer and Thermal Management Studies: The thermal stability and non-flammability of HFEs make them candidate fluids in experimental thermal management research.

Researchers should verify suitability for each specific application by consulting the product SDS and performing compatibility testing prior to use.

Safe Handling, Storage, and Disposal

Handling: Although HFEs are generally considered non-flammable and of lower acute toxicity than many conventional solvents, standard laboratory precautions apply. Use in a well-ventilated area or fume hood. Wear appropriate personal protective equipment (PPE): chemical-resistant gloves, safety glasses or goggles, and a lab coat. Avoid prolonged inhalation of vapors.

Storage: Store in a tightly sealed container in a cool, dry, well-ventilated location away from strong oxidizers and incompatible materials. Keep away from heat sources. Consult the product SDS for specific storage temperature recommendations.

Spill Management: In case of spill, absorb with an inert dry material and collect in an appropriate waste container. Ventilate the area. Avoid discharge to drains or waterways.

Disposal: Dispose of in accordance with local, regional, and national environmental regulations governing fluorinated organic waste. Do not pour down the drain. Contact a licensed waste disposal contractor.

Environmental Note: While HFEs have significantly lower global warming potential (GWP) and zero ozone depletion potential (ODP) compared to older chlorofluorocarbon (CFC) solvents, responsible disposal practices are still required.

Ordering Information and Quality Assurance

1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane is available from Aladdin Scientific under SKU N1320598. When placing an order, researchers and procurement staff should note the following:

• Purity and Grade: Confirm the purity specification and reagent grade on the current product page or CoA prior to ordering to ensure fitness for your specific application.
• Packaging: Available in research-scale quantities; consult the Aladdin Scientific product page for available pack sizes.
• Documentation: A Safety Data Sheet (SDS) and Certificate of Analysis (CoA) are available upon request or via the Aladdin Scientific website. Review the SDS before first use.
• Technical Support: For application-specific questions or custom requirements, contact Aladdin Scientific technical support.

For the most up-to-date pricing, availability, and regulatory information, visit the Aladdin Scientific website or contact your regional sales representative.

Frequently asked questions

What is 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane used for in research?

This hydrofluoroether is primarily used as a fluorinated solvent or co-solvent for dissolving fluorinated polymers, surfactants, and other fluorophilic compounds. It also finds use in precision cleaning of sensitive components, as a carrier fluid in surface-treatment studies, and as an inert reaction medium in specialty fluorine chemistry.

Is 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane flammable or hazardous?

As a hydrofluoroether, this compound is generally classified as non-flammable, which is one of its key safety advantages over hydrocarbon solvents. However, standard laboratory PPE—including chemical-resistant gloves, safety glasses, and adequate ventilation—should always be used. Consult the product Safety Data Sheet (SDS) for complete hazard information before handling.

How should I store 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane (SKU N1320598)?

Store in a tightly sealed container in a cool, dry, and well-ventilated area, away from strong oxidizers and heat sources. Always refer to the Aladdin Scientific product SDS for specific storage temperature ranges and compatibility warnings before storing or using this reagent.

How does this compound differ from perfluorocarbons (PFCs)?

Unlike fully fluorinated PFCs, 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane contains both a perfluoroalkyl segment and a hydrocarbon ether portion, making it a hydrofluoroether (HFE). This partial fluorination results in improved miscibility with common organic solvents, lower global warming potential, and generally more favorable toxicological profiles compared to PFCs, while retaining key benefits such as non-flammability and chemical inertness.

Where can I find the Certificate of Analysis (CoA) and Safety Data Sheet (SDS) for N1320598?

The CoA and SDS for 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane (SKU N1320598) are available on the Aladdin Scientific website on the product detail page, or by contacting Aladdin Scientific customer service directly. It is strongly recommended to review the SDS before first use.

References

1. Aladdin Scientific. Product page: 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane, SKU N1320598. Aladdin Scientific.
2. General reference: Hydrofluoroether (HFE) solvent class — physicochemical properties and applications. Textbook-level fluorine chemistry knowledge.
3. Safety Data Sheet for 1,1,1,2,2,3,3,4,4-Nonafluoro-6-propoxyhexane. [To be confirmed with Aladdin Scientific SDS document.]

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.