1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
A miRNA antagomir is an antisense oligonucleotide tool used to inhibit the function of a specific miRNA. It is commonly used to construct miRNA loss-of-function models, validate target gene derepression effects, and analyze the regulatory roles of miRNAs in disease development, cell ...
Nanozymes refer to nanomaterials with catalytic activities similar to natural enzymes. Under specific reaction conditions, they can mimic enzymatic functions such as peroxidase, oxidase, catalase and superoxide dismutase.
Vitronectin, laminin and fibronectin are commonly used extracellular matrix coating materials in cell culture. All three can improve cell adhesion, spreading and functional maintenance, but they differ significantly in receptor recognition, cell-type compatibility, culture objectives and ...
A miRNA inhibitor is a nucleic acid tool used to suppress endogenous miRNA function. It usually binds complementarily to the target miRNA and blocks its regulatory effect on target mRNAs. Its major application scenarios include miRNA loss-of-function studies, validation of target gene ...
De novo fatty acid synthesis refers to the process by which cells use small-molecule carbon sources such as glucose, glutamine, and acetate to synthesize fatty acids inside the cell, rather than relying directly on exogenous fatty acid supply. To study whether cancer cells depend on synthesizing ...
A miRNA agomir is a chemically modified nucleic acid tool used to enhance the function of a specific miRNA. It is commonly used to simulate increased endogenous miRNA expression or enhanced miRNA activity. Compared with ordinary miRNA mimics, agomirs place greater emphasis on stability, delivery ...
At first glance, graphene ink may seem straightforward: graphene has good electrical conductivity, flexibility, and chemical stability, so can’t we simply add graphene powder to a solvent, disperse it by ultrasonication, and obtain a conductive ink?
“Mimic” means “simulator” or “mimetic molecule.” In molecular biology experiments, a miRNA mimic usually refers to an artificially synthesized small RNA molecule used to simulate the function of an endogenous mature miRNA. Its main purpose is to enhance the functional level of a ...
Barium titanate is a typical perovskite oxide and an important base material for high-permittivity ceramic capacitor dielectrics. Its core value does not lie in light absorption, but in generating strong dielectric polarization under an electric field, enabling small-volume components to achieve ...