1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Boric acid (ester) is an important molecular synthesis block, especially special boric acid (ester) such as heterocyclic ring, allyl, saturated hydrocarbon and substrate containing two functional groups, are popular blocks in synthetic chemistry.
Remember the faint scent of jasmine on your first love, which you once thought was the smell of love, but in fact, this nice scent comes from a chemical called indole. However, it also has a familiar name - fecal odorant. As it turns out, indole and its derivatives almost always have this ...
Ellman's Sulfinamides, also known as tert-butylsulfinamides and 2-methyl-2-propanesulfinamides, are organosulfur compounds that are members of the sulfinamide family of compounds. Both enantiomeric forms are commercially available and are used as chiral auxiliaries in asymmetric synthesis, often ...
Magnetic resonance imaging (MRI) is a technology that uses the principle of nuclear magnetic resonance (NMR) plus a gradient magnetic field to detect emitted electromagnetic waves and draw images of the internal structure of objects.
A paper published August 24 at Org. Process Res. Dev by Professor Sean M. Kell et al. describes a robust and efficient continuous flow process technique for the synthesis of quinazoline organozinc reagents for KRAS G12C inhibitor divarasib.
Click Chemistry serves as a potent technique for investigating the intracellular distribution of small molecules. Unveiling the precise cellular destinations of these compounds provides profound insights into their mechanisms of action. This methodology has been extensively employed in various ...
Beverages, such as common sodas and energy drinks, may contain many polar ingredients that are easily dissolved in the aqueous matrix of the beverage. These ingredients include sweeteners (sugar or sugar substitutes), caffeine, vitamin supplements, amino acids, organic acids, and plant extracts. ...
As a prevalent click reaction, strain-promoted alkyne-azide cycloaddition (SPAAC) operates without the need for metal catalysts, reducing agents, or enduring ligands. Instead, it harnesses the enthalpy liberated from the inherent ring strain of cyclooctyne to facilitate the formation of stable ...
Strained alkenes leverage strain relief as a motivating factor, enabling their engagement in click reactions. Trans-cycloalkenes, typically cyclooctenes, and other strained alkenes like oxanorbornadiene, participate in click reactions with various counterparts, including azides, tetrazines, and ...