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Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.

5929 articles
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Antibody-drug Conjugates: A Comprehensive Guide

Antibody-drug conjugate (ADC) is an effective combination of chemotherapy and immunotherapy. The concept was first proposed more than 100 years ago by German scientist Paul Ehrlich. He likens ADCs to "wonder drugs" because they can clearly identify targets (cancer cells) without harming the ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

CRISPR/Cas9 and targeted genome editing

It is a long-term goal for biomedical researchers to develop efficient and reliable methods to make accurate and targeted changes in the genome of living cells. In recent years, a new tool based on bacterial CRISPR-associated protein-9 nuclease (Cas9) from Streptococcus pyogenes has aroused ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

In the field of tissue engineering and regenerative medicine, the design of biomaterial scaffolds that can reproduce the complex extracellular nature of living tissues in three dimensions is a challenging requirement. Hydrogels are a widely studied and developed class of synthetic extracellular ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

JAK-STAT Cell Signaling Pathway

The Janus kinase (JAK) signal transduction and transcriptional activator (STAT) pathway plays a key role in the signaling of a large number of cytokines and growth factors. These cytokines and growth factors are responsible for a variety of cellular functions, including proliferation, growth, ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

2-AA Labeling Kit-2-Picoline Borane

2-AA Labeling Kit-2-Picoline Borane

2025-06-10 03:33:47 Updated
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