Trifluoromethyl is one of the important chemical groups in the field of medicinal chemistry, and is widely used in bioactive molecules because of its high lipid solubility, excellent metabolic stability, high electronegativity and good bioavailability. The introduction of trifluoromethyl in drug ...
Biotechnology fields such as tissue engineering and drug delivery continue to grow with the increasing demand for diverse functional biomaterials. For decades, research in polymeric biomaterials has focused on testing the biocompatibility of polymers developed for other applications or their ...
In an atom or molecule, electrons usually occupy different energy levels. In solids, however, these energy levels coalesce to form bands. The energy band is divided into valence band and conduction band. The electrons used to hold the atoms together are in the valence band, while the remaining ...
Electrophoresis is an important step in many molecular biology applications. Therefore, problems encountered during nucleic acid electrophoresis may affect your handling of downstream applications and ultimately reduce the workflow efficiency of the experiment. In this section, common problems ...
Papain is an enzyme with a protein hydrolytic function and cysteine protease activity. The enzyme belongs to a superfamily that consists of a single polypeptide chain containing three disulfide bonds and a sulfhydryl group essential for enzymatic activity and is derived from the green papaya, ...
Due to the small radius of fluorine atom and its strongest electronegativity (4.0), the introduction of fluorine atom will change the polarity direction of C-F bond and the electron cloud distribution of the whole molecule, which will affect the dipole moment, acidity and basicity of the ...
The continuous development of solar energy technology is of great significance to human energy utilization. It is currently the cleanest and most abundant resource in the world. Solar energy can be harnessed in many ways, such as photovoltaic conversion and solar heating. The energy of solar ...
One of the most common post-translational modifications of eukaryotic proteins is glycosylation. Glycosylation of proteins can affect many biological activities. For therapeutic glycoproteins, it can alter biological activity, targeting, transport, serum half-life, clearance and receptor ...
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