10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Hyodeoxycholic acid (HDCA) Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥95%
| ALogP | 4.9 |
|---|
| Isomeric SMILES | C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)C |
|---|---|
| WGK Germany | 3 |
| Molecular Weight | 392.57 |
| Reaxy-Rn | 2950246 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2950246&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 200-201°C |
|---|
| 1. Cui Xiping, He Qiyi, Yang Huiyi, Chen Yingshan, Shen Ding, Eremin Sergei A., Mu Yunping, Zhao Suqing. (2021) Development of enzyme-free single-step immunoassays for glycocholic acid based on palladium nanoparticle-mediated signal generation. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413 (23): (5733-5742). [PMID:34476526] [10.1007/s00216-021-03548-5] |
| 2. Jiaxin Li, Yuqi Chen, Rui Li, Xianglong Zhang, Tao Chen, Fengyi Mei, Ruofan Liu, Meiling Chen, Yue Ge, Hongbin Hu, Rongjuan Wei, Zhenfeng Chen, Hongying Fan, Zhenhua Zeng, Yongqiang Deng, Haihua Luo, Shuiwang Hu, Shumin Cai, Feng Wu, Nengxian Shi, Zhang Wang, Yunong Zeng, Ming Xie, Yong Jiang, Zhongqing Chen, Wei Jia, Peng Chen. (2023) Gut microbial metabolite hyodeoxycholic acid targets the TLR4/MD2 complex to attenuate inflammation and protect against sepsis. MOLECULAR THERAPY, [PMID:36698311] [10.1016/j.ymthe.2023.01.018] |
| 3. Jiating Zheng, Xiaoru Peng, Taifeng Zhu, Shuyao Huang, Chao Chen, Guosheng Chen, Shuqin Liu, Gangfeng Ouyang. (2022) Detection of bile acids in small volume human bile samples via an amino metal-organic framework composite based solid-phase microextraction probe. JOURNAL OF CHROMATOGRAPHY A, [PMID:36345074] [10.1016/j.chroma.2022.463634] |
| 4. Ding Shen, Wei Hu, Suqing Zhao, Chuanbin Mao. (2021) Rapid Naked-Eye Detection of a Liver Disease Biomarker by Discovering Its Monoclonal Antibody to Functionalize Engineered Red-Colored Bacteria Probes. ACS Omega, [PMID:34870023] [10.1021/acsomega.1c04779] |
| 5. Qiyi He, Yanxiong Fang, Huiyi Yang, Ding Shen, Yingshan Chen, Yingying Zhong, Xiangguang Li, Sergei A. Eremin, Xiping Cui, Suqing Zhao. (2021) Enhanced performance of a surface plasmon resonance-based immunosensor for the detection of glycocholic acid. Analytical Methods, 13 (16): (1919-1924). [PMID:33913980] [10.1039/D1AY00357G] |
| 6. Ma Chongyang, Wang Xueqian, Xu Tian, Zhang Shuang, Liu Shuling, Zhai Changming, Wang Zisong, Mu Jie, Li Changxiang, Cheng Fafeng, Wang Qingguo. (2020) An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid. Frontiers in Pharmacology, [PMID:32457601] [10.3389/fphar.2020.00519] |
| 7. Yang Yang, Yang Cao, Yonghong Hu, Qi Zhang, Wenge Yang, Fei Shen. (2015) Thermodynamic analysis and correlation of solid–liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2015.07.005] |
| 8. Juan Zhou, Yi-Qiao Xu, Sheng-Ya Guo, Chun-Qi Li. (2014) Rapid analysis of hypolipidemic drugs in a live zebrafish assay. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, [PMID:25497901] [10.1016/j.vascn.2014.12.002] |
| 9. Yang Yang, Yonghong Hu, Qi Zhang, Limin Cheng, Cuicui Cao, Wenge Yang, Fei Shen. (2014) Experimental measurement and thermodynamic models for solid–liquid equilibrium of hyodeoxycholic acid in different organic solvents. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2014.12.007] |
| 10. Hao Zhi, Zhongyan Wang, Xinyue Zhu, Wenhan Wu, Lu Yang, Yidong Dai, Zehua Wang, Ling Jiang, Yongmei Tan, Xiaodong Liu, Li Liu. (2025) Chronic liver injury decreases levels of cerebral carnitine and acetylcarnitine in rats partly due to the downregulation of OCTs and OCTN2 at the blood-brain barrier. DRUG METABOLISM AND DISPOSITION, [PMID:40300306] [10.1016/j.dmd.2025.100072] |
| 11. Zhiye Yan, Weiwei Tang, Bin Li. (2025) Expanding Metabolome Coverage in LC–MS/MS Analysis through Hydralazine-Based Multifunctional Derivatization. ANALYTICAL CHEMISTRY, [PMID:41277254] [10.1021/acs.analchem.5c02101] |
