LAMTOR2 Antibody - Primärer Antikörper, specific to LAMTOR2, Rabbit IgG

Cat. No.: Ab112761

QUALITÄT & REINHEIT ExactAb™, Validated, 1.0 mg/mL

Application

WB

Host species

Kaninchen

Reactive species

Maus, Mensch

Isotype

Rabbit IgG

Conjugation

Unconjugated

Übersicht

Rabbit anti Human LAMTOR2 Antibody, Polyclonal, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Spezifikationen

Product Name

LAMTOR2 Antibody - Primärer Antikörper, specific to LAMTOR2, Rabbit IgG

Synonyme

ENDAPantibody | Endosomal adaptor protein p14 antibody | HSPC003antibody | LAMTOR2 antibody | Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2 antibody | Late endosomal/lysosomal Mp1 interacting protein antibody | Late endosomal/lysosomal Mp

Spezifikationen & Reinheit

ExactAb™, Validated, 1.0 mg/mL

Wirtsspezies

Kaninchen

Spezifität

LAMTOR2

Immunogen

A synthetic peptide derived from human LAMTOR2 (AA 10-90)

Positive Kontrolle

WB: U-2 OS, Hep G2, LNCaP, MCF7 and Raji cell lysates.

Konjugation

Unconjugated

Note

ExactAb™, Validated

Isotyp

Rabbit IgG

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Immunogen affinity purified

Konzentration

1.0 mg/mL

Product Line

Biologische Produkte

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Western Blot: LAMTOR2 Antibody (Ab112761)

LAMTOR2 Antibody (Ab112761) - Western Blot
All lanes: LAMTOR2 Antibody (Ab112761) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 13 kDa
Observed band size: 12 kDa
Exposure time: 1.9 s

Anwendung

Anwendung

Dilution info

WB

1/500-1/2000

Zugehörige Ziele (menschlich)

LAMTOR2 Tbio Ragulator complex protein LAMTOR2 (0 Activities)

Discover Target: LAMTOR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Häufig gestellte Fragen

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Validated mean?

Validated indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (LAMTOR2 Antibody); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.