Histon-Methyltransferase

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  1. GSK503
    CAS: 1346572-63-1 Summenformel: C31H38N6O2 Molekulargewicht: 526.67
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: G276508
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    N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-methyl-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindole-4-carboxamide
    SMILES
    CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C(=CN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C)C
    InChIKey
    HRDQQHUKUIKFHT-UHFFFAOYSA-N
    InChI
    1S/C31H38N6O2/c1-19(2)37-18-21(4)29-25(30(38)33-17-26-20(3)13-22(5)34-31(26)39)14-24(15-27(29)37)23-7-8-28(32-16-23)36-11-9-35(6)10-12-36/h7-8,13-16,1show more
    Synonyme
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyr...
  2. Furamidine dihydrochloride
    CAS: 55368-40-6 PubChem CID: 9799856 Summenformel: C18H16N4O · 2HCl Molekulargewicht: 377.27
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: F286803
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    4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride
    SMILES
    C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
    InChIKey
    VXNYQUQHOUERTR-UHFFFAOYSA-N
    InChI
    1S/C18H16N4O.2ClH/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22;;/h1-10H,(H3,19,20)(H3,21,22);2*1H
    Synonyme
    DB 75 | DB75 | NSC 305831 | WR199385 | 4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride ...
  3. ZLD 1039
    CAS: 1826865-46-6 PubChem CID: 132517142 Summenformel: C36H48N6O3 Molekulargewicht: 612.8
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: Z287041
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    3-[ethyl(oxan-4-yl)amino]-2-methyl-N-[(1-methyl-3-oxo-5,6,7,8-tetrahydro-2H-isoquinolin-4-yl)methyl]-5-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]benzamishow more
    SMILES
    CCN(C1CCOCC1)C2=CC(=CC(=C2C)C(=O)NCC3=C4CCCCC4=C(NC3=O)C)C5=CN=C(C=C5)N6CCN(CC6)C
    InChIKey
    SZAYCVHJDOWSNY-UHFFFAOYSA-N
    InChI
    1S/C36H48N6O3/c1-5-42(28-12-18-45-19-13-28)33-21-27(26-10-11-34(37-22-26)41-16-14-40(4)15-17-41)20-31(24(33)2)35(43)38-23-32-30-9-7-6-8-29(30)25(3)39-show more
    Synonyme
    3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-...
  4. (S)-PFI 2 hydrochloride
    CAS: 1627607-88-8 PubChem CID: 91691132 Summenformel: C₂₃H₂₅F₄N₃O₃S•HCl Molekulargewicht: 535.98
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: S287365
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    8-fluoro-N-[(2S)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride
    SMILES
    C1CCN(C1)C(=O)C(CC2=CC(=CC=C2)C(F)(F)F)NS(=O)(=O)C3=CC4=C(CNCC4)C(=C3)F.Cl
    InChIKey
    ZADKZNVAJGEFLC-BOXHHOBZSA-N
    InChI
    1S/C23H25F4N3O3S.ClH/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27;/h3-5,10,12-13,21,28-29show more
    Synonyme
    (S)-PFI-2 | 8-fluoro-N-[(2S)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoq...
  5. SGC 0946, Inhibitor of DOT1 like histone lysine methyltransferase
    CAS: 1561178-17-3 EG-Nummer: 808-588-8 PubChem CID: 56962337 Summenformel: C28H40BrN7O4 Molekulargewicht: 618.57
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S286970
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    1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urshow more
    SMILES
    CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=C(C4=C(N=CN=C43)N)Br)O)O
    InChIKey
    IQCKJUKAQJINMK-HUBRGWSESA-N
    InChI
    1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,1show more
    Synonyme
    1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(i...
  6. OICR 9429, Inhibitor of WD repeat domain 5
    CAS: 1801787-56-3 EG-Nummer: 109-667-3 Summenformel: C29H32F3N5O3 Molekulargewicht: 555.59
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: O287472
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    N-[2-(4-methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1H-pyridine-3-carboxamide
    SMILES
    CN1CCN(CC1)C2=C(C=C(C=C2)C3=CC=CC(=C3)CN4CCOCC4)NC(=O)C5=CNC(=O)C=C5C(F)(F)F
    InChIKey
    DJOVLOYCGXNVPI-UHFFFAOYSA-N
    InChI
    1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15show more
    Synonyme
    N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine...
  7. MS 023 dihydrochloride
    CAS: 1992047-64-9 PubChem CID: 121513886 Summenformel: C17H25N3O.2HCl Molekulargewicht: 360.32
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: M288905
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    N'-methyl-N'-[[4-(4-propan-2-yloxyphenyl)-1H-pyrrol-3-yl]methyl]ethane-1,2-diamine;dihydrochloride
    SMILES
    CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN.Cl.Cl
    InChIKey
    HCNXCUFNZWGILO-UHFFFAOYSA-N
    InChI
    1S/C17H25N3O.2ClH/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18;;/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3;2*1H
    Synonyme
    N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride
  8. NSC 663284 (DA3003-1)
    CAS: 383907-43-5 EG-Nummer: 636-814-3 Summenformel: C15H16ClN3O3 Molekulargewicht: 321.76
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: N275722
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    6-chloro-7-(2-morpholin-4-ylethylamino)quinoline-5,8-dione
    SMILES
    C1COCCN1CCNC2=C(C(=O)C3=C(C2=O)N=CC=C3)Cl
    InChIKey
    BMKPVDQDJQWBPD-UHFFFAOYSA-N
    InChI
    1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2
    Synonyme
    NCGC00092289-02 | 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione | NCI60_021732 | 5,6-chloro-7-[[2-(4-...
  9. Piribedil, Agonist of 5-HT 1A receptor;Antagonist of 5-HT 2B receptor;Antagonist of α 1A-adrenoceptor;Antagonist of α 2A-adrenoceptor;Antagonist of α 2C-adrenoceptor;Agonist of D 2 receptor;Agonist of D 3 receptor;Antagonist of D 4 receptor
    CAS: 3605-01-4 EG-Nummer: 222-764-6 PubChem CID: 4850 Summenformel: C16H18N4O2 Molekulargewicht: 298.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: P160771
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    2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
    SMILES
    C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4
    InChIKey
    OQDPVLVUJFGPGQ-UHFFFAOYSA-N
    InChI
    1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2
    Synonyme
    Oprea1_061309 | BRD-K47936004-003-03-1 | EU 4200 | PIRIBEDIL [MI] | AB00514645-19 | BRN 0963637 | CAS_3605-01-4 | ES-...
  10. Inhibitor 6e (PRMT1-Inhibitor 6e)
    CAS: 1025948-98-4 Summenformel: C20H7Br6NO5 Molekulargewicht: 820.7
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: I275552
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    4-amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
    SMILES
    C1=C2C(=C3C=C(C(=O)C(=C3OC2=C(C(=C1Br)O)Br)Br)Br)C4=C(C(=C(C=C4C(=O)O)Br)N)Br
    InChIKey
    PSILLVDSFALROT-UHFFFAOYSA-N
    InChI
    1S/C20H7Br6NO5/c21-7-3-6(20(30)31)11(12(24)15(7)27)10-4-1-8(22)16(28)13(25)18(4)32-19-5(10)2-9(23)17(29)14(19)26/h1-3,28H,27H2,(H,30,31)
    Synonyme
    4-Amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicacid
  11. Pinometostat (EPZ5676), Inhibitor of DOT1 like histone lysine methyltransferase
    CAS: 1380288-87-8 Summenformel: C30H42N8O3 Molekulargewicht: 562.71
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: E125307
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    (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-[[[3-[2-(6-tert-butyl-1H-benzimidazol-2-yl)ethyl]cyclobutyl]-propan-2-ylamino]methyl]oxolane-3,4-diol
    SMILES
    CC(C)N(CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C
    InChIKey
    LXFOLMYKSYSZQS-XKHGBIBOSA-N
    InChI
    1S/C30H42N8O3/c1-16(2)37(13-22-25(39)26(40)29(41-22)38-15-34-24-27(31)32-14-33-28(24)38)19-10-17(11-19)6-9-23-35-20-8-7-18(30(3,4)5)12-21(20)36-23/h7-show more
    Synonyme
    (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropy...
  12. UNC0638, Inhibitor of euchromatic histone lysine methyltransferase 1;Inhibitor of euchromatic histone lysine methyltransferase 2
    CAS: 1255580-76-7 PubChem CID: 46224516 Summenformel: C30H47N5O2 Molekulargewicht: 509.73
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: U275196
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    2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
    SMILES
    CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
    InChIKey
    QOECJCJVIMVJGX-UHFFFAOYSA-N
    InChI
    1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3show more
    Synonyme
    AC-32711 | AS-74910 | CCG-208706 | J-509244 | SB19045 | DTXSID30154787 | NSC764517 | NSC-764517 | 2-Cyclohexyl-6-meth...
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Häufig gestellte Fragen

What can I find under Histone Methyltransferase?
This listing collects compounds associated with Histone Methyltransferase within our Epigenetics area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Histone Methyltransferase?
Consider the reported potency of each Histone Methyltransferase compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Histone Methyltransferase compounds?
Each Histone Methyltransferase product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Histone Methyltransferase compounds by activity or structure?
Yes. Filter the Histone Methyltransferase listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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