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  1. ACHP
    CAS: 406208-42-2 Summenformel: C21H24N4O2 Molekulargewicht: 364.44
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: A288136
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    2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-piperidin-4-ylpyridine-3-carbonitrile
    SMILES
    C1CC1COC2=CC=CC(=C2C3=NC(=C(C(=C3)C4CCNCC4)C#N)N)O
    InChIKey
    DYVFBWXIOCLHPP-UHFFFAOYSA-N
    InChI
    1S/C21H24N4O2/c22-11-16-15(14-6-8-24-9-7-14)10-17(25-21(16)23)20-18(26)2-1-3-19(20)27-12-13-4-5-13/h1-3,10,13-14,24,26H,4-9,12H2,(H2,23,25)
    Synonyme
    2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-(4-piperidinyl)-3-pyridine-carbonitrile | 2-amino-6-[2-(cyclopro...
  2. GS 143
    CAS: 916232-21-8 Summenformel: C28H19FN2O4 Molekulargewicht: 466.46
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: G288221
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    4-[(4E)-3-benzyl-4-[[5-(2-fluorophenyl)furan-2-yl]methylidene]-5-oxopyrazol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)CC2=NN(C(=O)C2=CC3=CC=C(O3)C4=CC=CC=C4F)C5=CC=C(C=C5)C(=O)O
    InChIKey
    IZPMWFSVTDOCDI-HAVVHWLPSA-N
    InChI
    1S/C28H19FN2O4/c29-24-9-5-4-8-22(24)26-15-14-21(35-26)17-23-25(16-18-6-2-1-3-7-18)30-31(27(23)32)20-12-10-19(11-13-20)28(33)34/h1-15,17H,16H2,(H,33,34show more
    Synonyme
    4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid
  3. TBK1 PROTAC®3i, Inhibitor of TANK binding kinase 1
    CAS: 2052306-13-3 PubChem CID: 124108661 Summenformel: C53H74BrN9O9S Molekulargewicht: 1093.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: T287400
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    (2S,4R)-1-[(2S)-2-[[2-[3-[4-[3-[4-[[5-bromo-4-[3-[cyclobutanecarbonyl(methyl)amino]propylamino]pyrimidin-2-yl]amino]phenoxy]propoxy]butoxy]propoxy]aceshow more
    SMILES
    CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCCOCCCCOCCCOC4=CC=C(C=C4)NC5=NC=C(C(=N5)NCCCN(C)C(=O)C6CCC6)Br)O
    InChIKey
    QMGHHBHPDDAGGO-IIWOMYBWSA-N
    InChI
    1S/C53H74BrN9O9S/c1-36-46(73-35-58-36)38-16-14-37(15-17-38)31-56-49(66)44-30-41(64)33-63(44)51(68)47(53(2,3)4)60-45(65)34-71-28-10-26-69-24-6-7-25-70-show more
    Synonyme
    (2S,4R)-1-((S)-18-(4-((5-Brom-4-((3-(N-methylcyclobutanecarboxamido)propyl)amino)pyrimidin-2-yl)amino)phenoxy)-2-(ter...
  4. Resveratrol, Inhibitor of COX-2;Agonist of TAS2R14;Antagonist of Peroxisome proliferator-activated receptor-γ
    CAS: 501-36-0 EG-Nummer: 610-504-8 Summenformel: C14H12O3 Molekulargewicht: 228.24
    Feststoff Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: R107314
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    5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
    SMILES
    C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O
    InChIKey
    LUKBXSAWLPMMSZ-OWOJBTEDSA-N
    InChI
    1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
    Synonyme
    Q369O8926L | CHEBI:27881 | CU-01000001503-3 | HMS1792H15 | NSC133100 | BPBio1_000479 | NCGC00344093-09 | RESVERATROL ...
  5. ML 120B-Dihydrochlorid
    CAS: 1782573-78-7 PubChem CID: 90488985 Summenformel: C19H15ClN4O2•2HCl Molekulargewicht: 439.72
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: M287871
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    N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylpyridine-3-carboxamide;dihydrochloride
    SMILES
    CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4.Cl.Cl
    InChIKey
    AWKOVWFBTRXQLW-UHFFFAOYSA-N
    InChI
    1S/C19H15ClN4O2.2ClH/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16;;/h3-9,23H,1-2H3,(H,24,25);2*1H
    Synonyme
    N-(6-Chlor-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridincarboxamid Dihydrochlorid
  6. Nomilin
    CAS: 1063-77-0 Summenformel: C28H34O9 Molekulargewicht: 514.56
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: N115725
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    [(1R,2R,4S,7S,8S,11R,12R,13S,18R)-7-(furan-3-yl)-1,8,12,17,17-pentamethyl-5,15,20-trioxo-3,6,16-trioxapentacyclo[9.9.0.02,4.02,8.012,18]icosan-13-yl] show more
    SMILES
    CC(=O)OC1CC(=O)OC(C2C1(C3CCC4(C(OC(=O)C5C4(C3(C(=O)C2)C)O5)C6=COC=C6)C)C)(C)C
    InChIKey
    KPDOJFFZKAUIOE-WNGDLQANSA-N
    InChI
    1S/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19show more
    Synonyme
    CHEBI:7609 | NSC 297134 | AI3-00994 | (1S,3AS,4AR,4BR,6AR,11S,11AR,11BR,13AS)-11-(ACETYLOXY)-1-(3-FURANYL)DECAHYDRO-4...
  7. BMS 345541
    CAS: 445430-58-0 Summenformel: C14H17N5 Molekulargewicht: 255.32
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: B275312
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    N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
    SMILES
    CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
    InChIKey
    PSPFQEBFYXJZEV-UHFFFAOYSA-N
    InChI
    1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
    Synonyme
    Kinome_3215 | NCGC00165761-02 | AS-76298 | DTXSID60196216 | JEFFSOL GLYCERINE CARBONATE | N-(2-aminoethyl)-3,12-dimet...
  8. GSK319347A
    CAS: 862812-98-4 Summenformel: C22H19N3O5S2 Molekulargewicht: 469.53
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: I274644
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    5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile
    SMILES
    COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C#N)OCC4=CC=CC=C4S(=O)(=O)C)OC
    InChIKey
    LDTAHRLHGHFHKP-UHFFFAOYSA-N
    InChI
    1S/C22H19N3O5S2/c1-28-17-8-15-16(9-18(17)29-2)25(13-24-15)22-10-19(20(11-23)31-22)30-12-14-6-4-5-7-21(14)32(3,26)27/h4-10,13H,12H2,1-3H3
    Synonyme
    benzimidazole-thiophene carbonitrile, 12e | CHEBI:91459 | IKK-3 Inhibitor | EINECS 211-880-2 | BRD-K51781482-001-02-1...
  9. Amlexanox, Phosphodiesterase 4 inhibitor
    CAS: 68302-57-8 EG-Nummer: 804-135-3 Summenformel: C16H14N2O4 Molekulargewicht: 298.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: A136009
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    2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid
    SMILES
    CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
    InChIKey
    SGRYPYWGNKJSDL-UHFFFAOYSA-N
    InChI
    1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
    Synonyme
    AMLEXANOX (MART.) | CHX 3673 | OraDisc A | ANW | aphtheal | US10214536, Amlexanox | Amlexanox- Bio-X | 2-Amino-7-isop...
  10. PS-1145 dihydrochloride
    CAS: 1049743-58-9 Summenformel: C17H11ClN4O.2HCl Molekulargewicht: 395.67
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: P339439
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    N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide;dihydrochloride
    SMILES
    C1=CC(=CN=C1)C(=O)NC2=CC(=CC3=C2NC4=C3C=CN=C4)Cl.Cl.Cl
    InChIKey
    QTDCBADLGJZBHP-UHFFFAOYSA-N
    InChI
    1S/C17H11ClN4O.2ClH/c18-11-6-13-12-3-5-20-9-15(12)21-16(13)14(7-11)22-17(23)10-2-1-4-19-8-10;;/h1-9,21H,(H,22,23);2*1H
    Synonyme
    N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide dihydrochloride | PS-1145 2HCl
  11. Vinpocetine, Inhibitor of phosphodiesterase 1A;Inhibitor of phosphodiesterase 1C
    CAS: 42971-09-5 EG-Nummer: 256-028-0 PubChem CID: 443955 Summenformel: C22H26N2O2 Molekulargewicht: 350.45
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: V107535
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    ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate
    SMILES
    CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC
    InChIKey
    DDNCQMVWWZOMLN-IRLDBZIGSA-N
    InChI
    1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1
    Synonyme
    HMS1568F18 | vinpocetine | Apovincaminate d'ethyle | Vinporal | (41S,13aS)-ethyl 13a-ethyl-2,3,41,5,6,13a-hexahydro-1...
  12. Oxaprozin, Cyclooxygenase inhibitor
    CAS: 21256-18-8 EG-Nummer: 244-296-1 Summenformel: C18H15NO3 Molekulargewicht: 293.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: O129611
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    3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
    SMILES
    C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3
    InChIKey
    OFPXSFXSNFPTHF-UHFFFAOYSA-N
    InChI
    1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)
    Synonyme
    GTPL7252 | Lopac-O-9637 | SPBio_002940 | 3-(diphenyl-1,3-oxazol-2-yl)propanoic acid | Wy21743 | WY-21743 | BIDD:PXR01...
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Häufig gestellte Fragen

How is the IKK listing put together?
It draws on reported IKK annotations within NF-κB and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an IKK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IKK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for IKK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IKK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the IKK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of IKK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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