Mesp2 Antibody - Primärer Antikörper, specific to Mesp2, Rabbit IgG

Cat. No.: Ab115041

GRADE & PURITY Carrier Free, Validated, ExactAb™, 1.0 mg/mL

Application

WB

Host species

Kaninchen

Reactive species

Maus, Mensch, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Übersicht

Rabbit anti Human Mesp2 Antibody, Polyclonal, could be used for WB and so on.

Application

WB: 1/500-1/1000

Protein Function

Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.

Specifications

Product Name

Mesp2 Antibody - Primärer Antikörper, specific to Mesp2, Rabbit IgG

Synonyme

Basic helix loop helix protein MESP2 antibody | BHLH protein MesP2 antibody | bHLHc6 antibody | Class C basic helix-loop-helix protein 6 antibody | Hypothetical class II basic helix loop helix protein MESP 2 antibody | Hypothetical class II basic helix lo

Spezifikationen & Reinheit

ExactAb™, Validated, Carrier Free, 1.0 mg/mL

Wirtsspezies

Kaninchen

Spezifität

Mesp2

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MESP2.

Positive Kontrolle

WB: Mouse brain, SK-N-SH and NIH/3T3 lysates.

Konjugation

Unconjugated

Note

Carrier Free, ExactAb™, Validated

Isotyp

Rabbit IgG

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Immunogen affinity purified

Konzentration

1.0 mg/mL

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Western Blot: Mesp2 Antibody (Ab115041)

Mesp2 Antibody (Ab115041) - Western Blot
All lanes: Mesp2 Antibody (Ab115041) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 42 kDa
Observed band size: 42, 48 kDa
Exposure time: 104.7 s

Anwendung

• Anwendung: Dilution info
• WB:

  1/500-1/1000 ;

Zugehörige Ziele (menschlich)

MESP2 Tbio Mesoderm posterior protein 2 (0 Activities)

Discover Target: MESP2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Häufig gestellte Fragen

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Mesp2 Antibody); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.