Mibampator - 10mM in DMSO , Glutamate receptor ionotropic AMPA positive allosteric modulator, CAS No.375345-95-2, Glutamate receptor ionotropic AMPA positive allosteric modulator

CAS: 375345-95-2 Cat. No.: M655739 Summenformel: C₂₁H₃₀N₂O₄S₂ Molekulargewicht: 438.60 PubChem CID: 9889366

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.

In Vivo

Incubation of Mibampator (LY451395) with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in the in vivo metabolism studies of the preclinical species . LY404187 and Mibampator (LY451395) reverses the central effects of an acutely intoxicating dose of ethanol in the rat. Mibampator (LY451395) significantly and dose-dependently reversed ethanol-induced deficits in both motor coordination and disruptions in an operant task where animals were trained to press a lever for food reward . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:AMPA receptor

Specifications

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

POSITIVE ALLOSTERIC MODULATOR

Mechanismus der Wirkung

Glutamate receptor ionotropic AMPA positive allosteric modulator

Produkteigenschaften

• ALogP: 3.4

Namen und Kennungen

• Isomere SMILES: C[C@@H](CNS(=O)(=O)C(C)C)C1=CC=C(C=C1)C2=CC=C(C=C2)CCNS(=O)(=O)C
• Alternative CAS-Nummer: 375345-95-2
• PubChem CID: 9889366
• MeSH-Eintrag: LY 451395;LY-451395;LY451395;N-((2-(4'-(2-(methylsulfonyl)amino)ethyl)(1,1'-biphenyl)-4-yl)propyl)-2-propanesulfonamide
• Molekulargewicht: 438.60

Zugehörige Ziele (menschlich)

GRIA4 Tclin Glutamate receptor 4 (1 Activities)

Discover Target: GRIA4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Häufig gestellte Fragen

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 375345-95-2, the molecular formula is C21H30N2O4S2, and the molecular weight is 438.60 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.