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Glutamate receptor 4 (GRIA4)

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  1. Tezampanel, Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4
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    Tezampanel, Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4
    CAS: 154652-83-2 Formula: C13H21N5O2 Molecular Weight: 279.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: T125750
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    IUPAC Name
    (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid
    SMILES
    C1CC2CNC(CC2CC1CCC3=NNN=N3)C(=O)O
    InChIKey
    ZXFRFPSZAKNPQQ-YTWAJWBKSA-N
    InChI
    1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1
    Synonyms
    BDBM50494341 | TEZAMPANEL ANHYDROUS | Tezampanel, anhydrous | 1-Methyl-2-phenylethylamine | LY 293558 | ly215490 | GA...
  2. NBQX
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    NBQX
    CAS: 118876-58-7 EC Number: 621-100-6 Formula: C12H8N4O6S Molecular Weight: 336.28
    ≥99%
    In Stock Item #: N274693
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    IUPAC Name
    6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
    SMILES
    C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3
    InChIKey
    UQNAFPHGVPVTAL-UHFFFAOYSA-N
    InChI
    1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
    Synonyms
    2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfonic acid amide | BPBio1_001312 | SR-01000597617-1 | NBQX hydrate | B...
  3. Ampalex, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4
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    Ampalex, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4
    CAS: 154235-83-3 EC Number: 809-154-0 Formula: C14H15N3O Molecular Weight: 241.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: A125747
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    IUPAC Name
    piperidin-1-yl(quinoxalin-6-yl)methanone
    SMILES
    C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2
    InChIKey
    ANDGGVOPIJEHOF-UHFFFAOYSA-N
    InChI
    1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2
    Synonyms
    Ampalex i(1/4)OECX-516 | CHEBI:34605 | SCHEMBL194605 | Ampakine CX516 | BDP-12(Ampalex) | EX-A265 | Q5014875 | 9-Fluo...
  4. LY 404187, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4
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    LY 404187, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4
    CAS: 211311-95-4 Formula: C19H22N2O2S Molecular Weight: 342.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: L274875
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    IUPAC Name
    N-[2-[4-(4-cyanophenyl)phenyl]propyl]propane-2-sulfonamide
    SMILES
    CC(C)S(=O)(=O)NCC(C)C1=CC=C(C=C1)C2=CC=C(C=C2)C#N
    InChIKey
    HOQAVGZLYRYHSO-UHFFFAOYSA-N
    InChI
    1S/C19H22N2O2S/c1-14(2)24(22,23)21-13-15(3)17-8-10-19(11-9-17)18-6-4-16(12-20)5-7-18/h4-11,14-15,21H,13H2,1-3H3
    Synonyms
    75W6I8W6OU | A879241 | N-[2-(4'-Cyano[1,1'-biphenyl]-4-yl)propyl]-2-propanesulfonamide | N-[2-[4-(4-cyanophenyl)pheny...
  5. (S)-(-)-5-Fluorowillardiine, Agonist of GluA1;Agonist of GluA2;Agonist of GluA3;Agonist of GluA4
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    (S)-(-)-5-Fluorowillardiine, Agonist of GluA1;Agonist of GluA2;Agonist of GluA3;Agonist of GluA4
    CAS: 140187-23-1 EC Number: 634-285-3 Formula: C7H8FN3O4 Molecular Weight: 217.15
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F347382
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    IUPAC Name
    (2S)-2-amino-3-(5-fluoro-2,4-dioxopyrimidin-1-yl)propanoic acid
    SMILES
    C1=C(C(=O)NC(=O)N1CC(C(=O)O)N)F
    InChIKey
    DBWPFHJYSTVBCZ-BYPYZUCNSA-N
    InChI
    1S/C7H8FN3O4/c8-3-1-11(2-4(9)6(13)14)7(15)10-5(3)12/h1,4H,2,9H2,(H,13,14)(H,10,12,15)/t4-/m0/s1
    Synonyms
    (5S)-Fluorowillardiine | 5-Fluorowillardiine | J-007366 | KBio2_001794 | SR-01000597628-1 | EX-A4515 | F-205 | FWD | ...
  6. (S)-(-)-5-Iodowillardiine - ≥98%(HPLC), used for , CAS No. 140187-25-3, by Aladdin Scientific
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    (S)-(-)-5-Iodowillardiine, Agonist of GluK1
    CAS: 140187-25-3 PubChem CID: 447196 Formula: C7H8IN3O4 Molecular Weight: 325.06
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S286600
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    IUPAC Name
    (2S)-2-amino-3-(5-iodo-2,4-dioxopyrimidin-1-yl)propanoic acid
    SMILES
    C1=C(C(=O)NC(=O)N1CC(C(=O)O)N)I
    InChIKey
    AXXYLTBQIQBTES-BYPYZUCNSA-N
    InChI
    1S/C7H8IN3O4/c8-3-1-11(2-4(9)6(13)14)7(15)10-5(3)12/h1,4H,2,9H2,(H,13,14)(H,10,12,15)/t4-/m0/s1
    Synonyms
    (S)-(-)-5-IODOWILLARDIINE | IODO-WILLARDIINE | IWD | NCGC00024529-02 | NCGC00025270-06 | Q4639618 | 1mqg | W-110 | SR...
  7. Kainic acid - Moligand™, ≥98% CAS No(487-79-6) by Aladdin Scientific
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    Kainic acid
    CAS: 487-79-6 Formula: C10H15NO4 Molecular Weight: 213.233
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: K303803
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    IUPAC Name
    (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid
    SMILES
    CC(=C)C1CNC(C1CC(=O)O)C(=O)O
    InChIKey
    VLSMHEGGTFMBBZ-OOZYFLPDSA-N
    InChI
    1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
    Synonyms
    Acide kainique | Digenic acid | Helminal | L-alpha-Kainic acid | Kainsaeure | Digenin | Acidum kainicum | Kainate | A...
  8. Kainic acid, Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
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    Kainic acid, Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
    CAS: 487-79-6 Formula: C10H15NO4 Molecular Weight: 213.233
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: K276587
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    Technical Identifiers
    IUPAC Name
    (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid
    SMILES
    CC(=C)C1CNC(C1CC(=O)O)C(=O)O
    InChIKey
    VLSMHEGGTFMBBZ-OOZYFLPDSA-N
    InChI
    1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
    Synonyms
    Acide kainique | Digenic acid | Helminal | L-alpha-Kainic acid | Digenin | kainic acid | Kainate | Acido kainico | Di...
  9. (RS)-AMPA - Moligand™, ≥98% CAS No(77521-29-0) by Aladdin Scientific
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    (RS)-AMPA, Agonist of GluA1;Agonist of GluA2;Agonist of GluA3;Agonist of GluA4
    CAS: 77521-29-0 Formula: C7H10N2O4·H2O Molecular Weight: 204.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: R288477
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    IUPAC Name
    2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
    SMILES
    CC1=C(C(=O)NO1)CC(C(=O)O)N
    InChIKey
    UUDAMDVQRQNNHZ-UHFFFAOYSA-N
    InChI
    1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)
    Synonyms
    GTPL4077 | (+/-)-alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID | (R)-2-Amino-3-(3-hydroxy-5-methyl-isoxazo...
  10. Ampalex, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4
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    Ampalex, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4
    CAS: 154235-83-3 EC Number: 809-154-0 Formula: C14H15N3O Molecular Weight: 241.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421836
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    Technical Identifiers
    IUPAC Name
    piperidin-1-yl(quinoxalin-6-yl)methanone
    SMILES
    C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2
    InChIKey
    ANDGGVOPIJEHOF-UHFFFAOYSA-N
    InChI
    1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2
    Synonyms
    Ampalex i(1/4)OECX-516 | CHEBI:34605 | SCHEMBL194605 | Ampakine CX516 | BDP-12(Ampalex) | EX-A265 | Q5014875 | 9-Fluo...
  11. NBQX
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    NBQX
    CAS: 118876-58-7 EC Number: 621-100-6 Formula: C12H8N4O6S Molecular Weight: 336.28
    10mM in DMSO
    In Stock Item #: N420833
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    Technical Identifiers
    IUPAC Name
    6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
    SMILES
    C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3
    InChIKey
    UQNAFPHGVPVTAL-UHFFFAOYSA-N
    InChI
    1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
    Synonyms
    2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfonic acid amide | BPBio1_001312 | SR-01000597617-1 | NBQX hydrate | B...
  12. cyclothiazide, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4;Inhibitor of Na-Cl symporter
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    cyclothiazide, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4;Inhibitor of Na-Cl symporter
    CAS: 2259-96-3 EC Number: 218-859-7 Formula: C14H16ClN3O4S2 Molecular Weight: 389.87
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C137530
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    Technical Identifiers
    IUPAC Name
    3-(2-bicyclo[2.2.1]hept-5-enyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
    SMILES
    C1C2CC(C1C=C2)C3NC4=CC(=C(C=C4S(=O)(=O)N3)S(=O)(=O)N)Cl
    InChIKey
    BOCUKUHCLICSIY-UHFFFAOYSA-N
    InChI
    1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)
    Synonyms
    6-Chloro-3，4-dihydro-3-(2-norbornen-5-yl)-2H-1，2-4-benzothiadiazine-7-sulfonamide 1，1-dioxide
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