MK1064 - Moligand™, 10mM in DMSO , Antagonist of OX 1 receptor;Antagonist of OX 2 receptor, CAS No.1207253-08-4, Antagonist of OX 1 receptor;Antagonist of OX 2 receptor

CAS: 1207253-08-4 Cat. No.: M420908 Summenformel: C₂₄H₂OClN₅O₃ Molekulargewicht: 461.9 EG-Nummer: 837-430-0

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

AC-36061 | BCP19608 | SB16800 | Urokinase inhibitor 1 | A16360 | AS-74199 | D84025 | GTPL9306 | 1207253-08-4 | MK1064 | mk-1064 | UNII-O812716S9E | PENTAMIDINE ISETHIONATE [USP-RS] | BDBM50028059 | (2,2':5',3''-Terpyridine)-3'-carboxamide, 5''-chloro-N-((

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

MK1064 MK1064 is a selective orexin 2 receptor antagonist (2-SORA) with an IC50 of 18 nM.

Targets

orexin\u20052 receptor 18 nM

Specifications

Synonyme

AC-36061 | BCP19608 | SB16800 | Urokinase inhibitor 1 | A16360 | AS-74199 | D84025 | GTPL9306 | 1207253-08-4 | MK1064 | mk-1064 | UNII-O812716S9E | PENTAMIDINE ISETHIONATE [USP-RS] | BDBM50028059 | (2,2':5',3''-Terpyridine)-3'-carboxamide, 5''-chloro-N-((

Spezifikationen & Reinheit

Moligand™, 10mM in DMSO

Biochemische und physiologische Mechanismen

MK1064 is a selective orexin\u20052 receptor antagonist (2-SORA) with an IC50 of 18 nM.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

ANTAGONIST

Mechanismus der Wirkung

Antagonist of OX 1 receptor;Antagonist of OX 2 receptor

Produkteigenschaften

• ALogP: 3.298
• hba_count: 7
• HBD-Zahl: 1
• Rotationsfähige Bindung: 7

Namen und Kennungen

• Isomere SMILES: COC1=C(N=C(C=C1)CNC(=O)C2=C(N=CC(=C2)C3=CC(=CN=C3)Cl)C4=CC=CC=N4)OC
• Molekulargewicht: 461.9
• Reaxy-Rn: 20001765
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20001765&ln=

Zugehörige Ziele (menschlich)

HCRTR1 Tclin Orexin receptor type 1 (1 Activities)

Discover Target: HCRTR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCRTR2 Tclin Orexin receptor type 2 (4 Activities)

Discover Target: HCRTR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemische und physikalische Eigenschaften

• DMSO (mg/ml) Maximale Löslichkeit: 92
• DMSO (mM) Maximale Löslichkeit: 199.1773111063
• Wasser (mg/ml) Maximale Löslichkeit: ＜1

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1207253-08-4, the molecular formula is C24H2OClN5O3, and the molecular weight is 461.9 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.