NADPH (Tetracyclohexanamin) - ≥96% , CAS No.100929-71-3

CAS: 100929-71-3 Cat. No.: N302057 Summenformel: C₄₅H₈₂N₁₁O₁₇P₃ Molekulargewicht: 1142.12 PubChem CID: 71312102

GRADE & PURITY ≥96%

Synonyms

NADPH (tetracyclohexanamine) | MFCD00079504 | beta-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt | HY-F0003A | beta-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt, >=95% | NADPH te

Storage

Lagerung bei -20°C

Shipped In

Eistruhe + Eispads

Übersicht

β-Nicotinamid-Adenin-Dinukleotid-2′-Phosphat (NADP+) und β-Nicotinamid-Adenin-Dinukleotid-2′-Phosphat, reduziert (NADPH) bilden ein Coenzym-Redoxpaar (NADP+:NADPH), das an einer Vielzahl von enzymkatalysierten Oxidations-Reduktionsreaktionen beteiligt ist. Das NADP+/NADPH-Redoxpaar erleichtert den Elektronentransfer bei anabolen Reaktionen wie der Lipid- und Cholesterinbiosynthese und der Verlängerung der Fettacylketten. Das NADP+/NADPH-Redoxpaar wird in einer Reihe von Antioxidationsmechanismen eingesetzt, wo es vor der Ansammlung reaktiver Oxidationsspezies schützt. NADPH wird in vivio durch den Pentosephosphat-Weg (PPP) erzeugt.

Specifications

Synonyme

NADPH (tetracyclohexanamine) | MFCD00079504 | beta-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt | HY-F0003A | beta-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt, >=95% | NADPH te

Spezifikationen & Reinheit

≥96%

Biochemische und physiologische Mechanismen

Elektronendonator; Kofaktoren der Stickstoffoxid-Synthase

Storage

Lagerung bei -20°C

Verschickt in

Eistruhe + Eispads

Aktionsart

INHIBITOR

Reinheit

≥96%

Namen und Kennungen

Pubchem Sid

528775802

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528775802

Kanonisches Lächeln

C1CCC(CC1)N.C1CCC(CC1)N.C1CCC(CC1)N.C1CCC(CC1)N.C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O

IUPAC Name

[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate;cyclohexanamine

InChIKey

PTKRUDMLGIIORX-ITGWJZMWSA-N

INCHI

1S/C21H30N7O17P3.4C6H13N/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;4*7-6-4-2-1-3-5-6/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);4*6H,1-5,7H2/t10-,11-,13-,14-,15-,16-,20-,21-;;;;/m1..../s1

Isomere SMILES

C1CCC(CC1)N.C1CCC(CC1)N.C1CCC(CC1)N.C1CCC(CC1)N.C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O

PubChem CID

71312102

Molekulargewicht

1142.12

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Klasse (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Klasse: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside 2',5'-bisphosphates Nicotinamide nucleotides Pentose phosphates Glycosylamines 6-aminopurines Organic pyrophosphates N-substituted nicotinamides Monosaccharide phosphates Aminopyrimidines and derivatives Cyclohexylamines Dihydropyridines Monoalkyl phosphates Imidolactams N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Secondary alcohols Amino acids and derivatives Primary carboxylic acid amides Oxacyclic compounds Enamines Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Monoalkylamines
• Molecular Framework: Not available
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside 2',5'-bisphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside diphosphate - Nicotinamide-nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Organic pyrophosphate - Monosaccharide phosphate - N-substituted nicotinamide - Purine - Imidazopyrimidine - Monoalkyl phosphate - Dihydropyridine - Cyclohexylamine - Aminopyrimidine - Imidolactam - Alkyl phosphate - Organic phosphoric acid derivative - Hydropyridine - Monosaccharide - Phosphoric acid ester - N-substituted imidazole - Pyrimidine - Vinylogous amide - Heteroaromatic compound - Oxolane - Azole - Imidazole - Amino acid or derivatives - Carboxamide group - Secondary alcohol - Primary carboxylic acid amide - Carboxylic acid derivative - Oxacycle - Organoheterocyclic compound - Azacycle - Enamine - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Alcohol - Carbonyl group - Organic oxide - Organic oxygen compound - Primary amine - Primary aliphatic amine - Organooxygen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Molekulargewicht: 1142.100 g/mol
• Hydrogen Bond Donor Count: 13
• Hydrogen Bond Acceptor Count: 26
• Rotatable Bond Count: 13
• Exact Mass: 1141.51 Da
• Monoisotopic Mass: 1141.51 Da
• Topological Polar Surface Area: 468.000 Ų
• Heavy Atom Count: 76
• Formal Charge: 0
• Complexity: 1450.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 5

XLogP3