NADPH - ≥93% , CAS No.2646-71-1

CAS: 2646-71-1 Cat. No.: N276326 Summenformel: C₂₁H₂₆N₇Na₄O₁₇P₃ · xH₂O Molekulargewicht: 833.35 (anhydrous basis) EG-Nummer: 220-163-3

GRADE & PURITY ≥93%

Synonyms

NADPH Na4 | TPNH2 Na4 | AS-10522 | C21H26N7O17P3Na4 | A-NADPH | HB4469 | C74369 | MFCD00036263 | beta-Nicotinamide adenine dinucleotide phosphate reduced tetrasodium salt | NADPH tetrasodium salt (reduced form) | Dihydronicotinamide-adenine dinucleotide p

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Übersicht

Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.

Specifications

Synonyme

NADPH Na4 | TPNH2 Na4 | AS-10522 | C21H26N7O17P3Na4 | A-NADPH | HB4469 | C74369 | MFCD00036263 | beta-Nicotinamide adenine dinucleotide phosphate reduced tetrasodium salt | NADPH tetrasodium salt (reduced form) | Dihydronicotinamide-adenine dinucleotide p

Spezifikationen & Reinheit

≥93%

Biochemische und physiologische Mechanismen

Ubiquitous coenzyme and biological reducing agent that acts as an electron donor for many redox enzymes including nitric oxide synthetase. Generated by reduction of the electron acceptor NADP+.

Storage

Protected from light,Store at -20°C,Desiccated

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥93%

Namen und Kennungen

Pubchem Sid

488201525

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488201525

Kanonisches Lächeln

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

IUPAC Name

tetrasodium;[(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]-4-hydroxyoxolan-3-yl] phosphate

InChIKey

WYWWVJHQDVCHKF-ITGWJZMWSA-J

INCHI

1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11-,13-,14-,15-,16-,20-,21-;;;;/m1..../s1

Isomere SMILES

C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O.[Na+].[Na+].[Na+].[Na+]

Molekulargewicht

833.35 (anhydrous basis)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Klasse (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Klasse: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside 2',5'-bisphosphates Nicotinamide nucleotides Pentose phosphates Glycosylamines Monosaccharide phosphates 6-aminopurines N-substituted nicotinamides Organic pyrophosphates Aminopyrimidines and derivatives Dihydropyridines Alkyl phosphates Imidolactams N-substituted imidazoles Heteroaromatic compounds Vinylogous amides Oxolanes Primary carboxylic acid amides Secondary alcohols Amino acids and derivatives Enamines Oxacyclic compounds Azacyclic compounds Organic oxides Hydrocarbon derivatives Organic zwitterions Carbonyl compounds Primary amines Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside 2',5'-bisphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside diphosphate - Nicotinamide-nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - N-substituted nicotinamide - Organic pyrophosphate - Imidazopyrimidine - Purine - Aminopyrimidine - Dihydropyridine - Imidolactam - Alkyl phosphate - Hydropyridine - Pyrimidine - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Vinylogous amide - Azole - Imidazole - Heteroaromatic compound - Oxolane - Carboxamide group - Primary carboxylic acid amide - Secondary alcohol - Amino acid or derivatives - Organoheterocyclic compound - Carboxylic acid derivative - Enamine - Organic alkali metal salt - Azacycle - Oxacycle - Alcohol - Organic zwitterion - Organic sodium salt - Organic salt - Organic oxygen compound - Primary amine - Carbonyl group - Organic oxide - Organooxygen compound - Amine - Organic nitrogen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: 10 mM NaOH: soluble 50 mg/mL, clear
• Empfindlichkeit: light sensitive;Heat sensitive
• Molekulargewicht: 833.300 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 22
• Rotatable Bond Count: 12
• Exact Mass: 833.019 Da
• Monoisotopic Mass: 833.019 Da
• Topological Polar Surface Area: 375.000 Ų
• Heavy Atom Count: 52
• Formal Charge: 0
• Complexity: 1380.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 5

XLogP3