Sodium ascorbate - for cell culture, ≥99% , CAS No.134-03-2

CAS: 134-03-2 Cat. No.: S105026 Summenformel: C₆H₇NaO₆ Molekulargewicht: 198.11 Beilstein Registry Number: 3767246 EG-Nummer: 205-126-1 PubChem CID: 23667548

GRADE & PURITY for Cell culture, ≥99%

Synonyms

L-Ascorbic acid, monosodium salt | sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate | Vitamin C Sodium Salt | (+)-Sodium L-ascorbate | SODIUM ASCORBATE | 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate | SODIUM ASCORBATE (US

Storage

Protected from light,Room temperature,Argon charged

Shipped In

Normal

Übersicht

Sodium ascorbate is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid).[1][2] It is widely used as a food additive.[1] In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture.[3] Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats.[1] sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.

Application：
Sodium ascorbate has been used:
· to produce H2O2 in cell culture media;
· as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD);
· to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat.  

Specifications

Synonyme

L-Ascorbic acid, monosodium salt | sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate | Vitamin C Sodium Salt | (+)-Sodium L-ascorbate | SODIUM ASCORBATE | 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate | SODIUM ASCORBATE (US

Spezifikationen & Reinheit

for cell culture, ≥99%

Storage

Protected from light,Room temperature,Argon charged

Verschickt in

Normal

Note

für die Zellkultur

Reinheit

≥99%

Namen und Kennungen

Pubchem Sid

508813564

Kanonisches Lächeln

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

IUPAC Name

sodium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate

InChIKey

PPASLZSBLFJQEF-RXSVEWSESA-M

INCHI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

Isomere SMILES

C([C@@H]([C@@H]1C(=C(C(=O)O1)O)[O-])O)O.[Na+]

WGK Deutschland

1

RTECS

CI7671000

PubChem CID

23667548

Molekulargewicht

198.11

Beilstein

3767246

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Dihydrofurans
      • Subclass Furanones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Dihydrofurans
• Subclass: Furanones
• Intermediate Tree Nodes: Not available
• Direct Parent: Butenolides
• Alternative Parents: Vinylogous acids Enoate esters Secondary alcohols Lactones 1,2-diols Oxacyclic compounds Monocarboxylic acids and derivatives Primary alcohols Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-furanone - Enoate ester - Alpha,beta-unsaturated carboxylic ester - Vinylogous acid - 1,2-diol - Carboxylic acid ester - Lactone - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Oxacycle - Organic alkali metal salt - Hydrocarbon derivative - Organic oxide - Organic zwitterion - Organic oxygen compound - Primary alcohol - Organooxygen compound - Alcohol - Carbonyl group - Organic salt - Organic sodium salt - Aliphatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

FFAR3 Tchem Free fatty acid receptor 3 (304 Activities)

Discover Target: FFAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CRYAB Tchem Alpha-crystallin B chain (132 Activities)

Discover Target: CRYAB

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Zugehörige Ziele (nicht menschlich)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in water. Slightly soluble in alcohol. Insoluble in chloroform and ether.
• Empfindlichkeit: Light & Moisture & Air sensitive
• Spezifische Drehung [α]: 105.5 ° (C=10, H2O)
• Schmelzpunkt (°C): 219-221°C
• Molekulargewicht: 198.110 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 198.014 Da
• Monoisotopic Mass: 198.014 Da
• Topological Polar Surface Area: 110.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 237.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3