Squalane - ≥95% , CAS No.111-01-3

CAS: 111-01-3 Cat. No.: S141278 Molecular Weight: 422.81 Beilstein Registry Number: 776019 EC Number: 203-825-6 PubChem CID: 8089

GRADE & PURITY ≥95%

Synonyms

squalane-d62 | CAS-111-01-3 | Dodecahydrosqualene | Spinacane | Hexamethyltetracosane | SQUALANE | Robane | Pripure 3759 | Squalane [NF] | Cosbiol | Tetracosane, 2,6,10,15,19,23-hexamethyl- | NSC 6851 | Perhydrosqualene | 2,6,10,15,19,23-Hexamethyltetraco

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Product Describtion:

Dielectrophoretic deformation of thin liquid fillm of squalane has been investigated.Microfluidized squalenes are efficient adjuvants, eliciting both humoral and cellular immune responses.

Product Application：
Squalane has been used: as solvent in the synthesis of Europium dibenzoylmethide triethylammonium, brightest known triboluminescent (TL) material;as lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces

Squalane influence on the vital pathway that transforms glucose into cholesterol may be pivotal. It regulates or controls the rate of synthesis of the enzyme HMG Co-A reductase, and may contribute to effective treatments for cancer and heart disease. It plays an important role as a terminator in the biomembrane.

Specifications

Synonyms

squalane-d62 | CAS-111-01-3 | Dodecahydrosqualene | Spinacane | Hexamethyltetracosane | SQUALANE | Robane | Pripure 3759 | Squalane [NF] | Cosbiol | Tetracosane, 2, 6, 10, 15, 19, 23-hexamethyl- | NSC 6851 | Perhydrosqualene | 2, 6, 10, 15, 19, 23-Hexamethyltetraco

Specifications & Purity

≥95%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Canonical Smiles: CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C
• IUPAC Name: 2,6,10,15,19,23-hexamethyltetracosane
• InChIKey: PRAKJMSDJKAYCZ-UHFFFAOYSA-N
• INCHI: 1S/C30H62/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h25-30H,9-24H2,1-8H3
• Isomeric SMILES: CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C
• WGK Germany: 3
• RTECS: XB6070000
• PubChem CID: 8089
• Molecular Weight: 422.81
• Beilstein: 776019
• Reaxy-Rn: 776019

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Prenol lipids
      • Subclass Triterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Prenol lipids
• Subclass: Triterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Triterpenoids
• Alternative Parents: Branched alkanes
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Triterpenoid - Branched alkane - Acyclic alkane - Saturated hydrocarbon - Alkane - Hydrocarbon - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in ether, chloroform, benzene, slightly soluble in ethanol, acetone, methanol, insoluble in water
• Refractive Index: 1.45-1.452
• Flash Point(°F): 424.4 °F
• Flash Point(°C): 218 °C
• Boil Point(°C): 350 °C
• Melt Point(°C): -38 °C
• Molecular Weight: 422.800 g/mol
• XLogP3: 14.700
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 21
• Exact Mass: 422.485 Da
• Monoisotopic Mass: 422.485 Da
• Topological Polar Surface Area: 0.000 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 308.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 4
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Zhong yuan You, Xin Wang, Fuqi Lu, Shuting Wang, Bingxi Hu, Lian Li, Weihai Fang, Ying Liu.  (2023)  An organic semiconductor/metal Schottky heterojunction based direct current triboelectric nanogenerator windmill for wind energy harvesting.  Nano Energy,      [PMID:] [10.1016/j.nanoen.2023.108302]

2. Yue Zhang, Wenxiu Pan, Dequan Wang, Han Wang, Yanting Hou, Meijuan Zou, Hongyu Piao.  (2023)  Solid-in-oil nanodispersion as a novel topical transdermal delivery to enhance stability and skin permeation and retention of hydrophilic drugs l-ascorbic acid.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:36791884] [10.1016/j.ejpb.2023.02.004]

3. Bowen Du, Xiao Chen, Yu Ling, Tiantian Niu, Weixiang Guan, Jipeng Meng, Haoquan Hu, Chi-Wing Tsang, Changhai Liang.  (2022)  Hydrogenolysis-Isomerization of Waste Polyolefin Plastics to Multibranched Liquid Alkanes.  ChemSusChem,  16  (3): (e202202035).  [PMID:36480423] [10.1002/cssc.202202035]

4. Anning Liu, Huijuan Jing, Xiaojing Du, Chaoyang Ma, Hongxin Wang.  (2022)  Efficient Ultrasonic-assisted Aqueous Enzymatic Method for Pecan Nut Kernel Oil Extraction with Quality Analysis.  Journal of Oleo Science,      [PMID:36464287] [10.5650/jos.ess22119]

5. Shuai Kong, Chong Shen, Yulu Luo, Qin Meng.  (2020)  Synthesis and Characterization of Fluorescent Surfactants for Studying the Penetration of Cosmetic Surfactants on the Skin.  JOURNAL OF SURFACTANTS AND DETERGENTS,  23  (5): (937-943).  [PMID:] [10.1002/jsde.12416]

6. Junjin Duan, Yanqin Huang, Fuqing Wei, Jiachun Feng.  (2025)  A Fluorescent Polyethylene With Good Processability and Mechanical Flexibility Prepared by a One-Step Melt Mixing Strategy.  Advanced Materials Technologies,      [PMID:] [10.1002/admt.202402203]

7. Mengjiao Liu, Xin Zhang, Yue Xin, Dongxu Guo, Guangkai Hu, Yifei Ma, Bin Yu, Tao Huang, Chengchang Ji, Meifang Zhu, Hao Yu.  (2024)  Earthworm-Inspired Ultra-Durable Sliding Triboelectric Nanogenerator with Bionic Self-Replenishing Lubricating Property for Wind Energy Harvesting and Self-Powered Intelligent Sports Monitoring.  Advanced Science,  11  (28): (2401636).  [PMID:38741379] [10.1002/advs.202401636]

8. Wanling Chen, Nanxi Xiang, Jiahong Huang, Huixian Xu, Zhenyuan Wang, Bo Ruan, Jichuan Zhang, Chengyu Wu, Jiaheng Zhang, YanZhen Liang.  (2024)  Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:39383579] [10.1016/j.colsurfb.2024.114275]

9. Dengliang Cai, Guangxin Zhao, Wenan Tie, Ting Lei, Jiachun Feng.  (2025)  myo-Inositol as a Biobased Multifunctional Additive: Simultaneous Enhancement of Thermo-Oxidative Stability and Crystallization Kinetics in Vitamin E Stabilized Polypropylene.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.5c03570]

10. Minjia Yuan, Zhihui Zheng, Yan Yu, Yi Wang, Wenxing Wang, Qi Li, Xiaomin Li, Dongyuan Zhao.  (2026)  Topology-enhanced oil adsorption by flower-like mesoporous silica nanoparticles for advanced cosmetic oil control.  RSC Advances,  16  (8): (6865-6875).  [PMID:41635760] [10.1039/D5RA08525J]

11. Xiaoru Wang, Zhanwu Lei, Jicong Yan, Penglong Wang, Ruifeng Chong, Fuping Tian, Tao Hu, Ruiguo Cao, Xiang Wang.  (2026)  Hydrocracking Polyolefins to Jet Fuel over a NiW/WOx Catalyst.  ACS Catalysis,      [PMID:] [10.1021/acscatal.5c07128]

12. Tu Weilin, Chu Mingyu, Yan Tianran, Zhang Qingqing, Wang Xianpeng, Zhang Liang, Cao Muhan, Zhang Qiao, Zhu Mingshan, Zhan Mingxiu, Chen Jinxing.  (2026)  One-pot co-upcycling of mixed polyolefin waste.  Nature Communications,      [PMID:] [10.1038/s41467-026-70104-z]