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TH287 - ≥98% , CAS No.1609960-30-6

CAS: 1609960-30-6 Cat. No.: T305079 Summenformel: C11H10Cl2N4 Molekulargewicht: 269.13 PubChem CID: 73441664
COA
TH287 - ≥98% CAS No(1609960-30-6) by Aladdin Scientific
Zu bestellen verfügbar
GRADE & PURITY ≥98%
Synonyms
SCHEMBL15757374 | (S)-N-(6-chloro-5-(2-(5-(2-fluoro-4-methylphenyl)-2-methyl-7,8-dihydro-[1,3,4]thiadiazolo[2?,3?:2,3]imidazo[4,5-c]pyridin-6(5H)-yl)- 2-oxoethoxy)pyridin-2-yl)methanesulfonamide | UNII-R6DCB5MSM2 | TH287 | TH-287 | CCG-267139 | Q27452986
Storage
Lagerung bei -20°C
Shipped In
Eistruhe + Eispads
★
Size
Deutschland (EU)
USA*
Price
Qty
5mg
T305079-5mg
—
2 Auf Lager

61,52€

92,76€
Speichern 31,24 € (33.68%)
10mg
T305079-10mg
—
2 Auf Lager

79,75€

119,66€
Speichern 39,92 € (33.36%)
25mg
T305079-25mg
—
2 Auf Lager

103,17€

155,24€
Speichern 52,06 € (33.54%)
50mg
T305079-50mg
—
2 Auf Lager

174,33€

261,97€
Speichern 87,64 € (33.45%)
100mg
T305079-100mg
Auf Bestellung · 8–12 Wochen

295,81€

444,20€
Speichern 148,38 € (33.40%)
250mg
T305079-250mg
Auf Bestellung · 8–12 Wochen

560,47€

840,75€
Speichern 280,28 € (33.34%)
Enter a quantity for the sizes you want to add.
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Lösungsrechner Bewertungen
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Lagerung bei -20°C Ships Eistruhe + Eispads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyme
SCHEMBL15757374 | (S)-N-(6-chloro-5-(2-(5-(2-fluoro-4-methylphenyl)-2-methyl-7,8-dihydro-[1,3,4]thiadiazolo[2?,3?:2,3]imidazo[4,5-c]pyridin-6(5H)-yl)- 2-oxoethoxy)pyridin-2-yl)methanesulfonamide | UNII-R6DCB5MSM2 | TH287 | TH-287 | CCG-267139 | Q27452986
Spezifikationen & Reinheit
≥98%
Biochemische und physiologische Mechanismen
TH287 ist ein potenter Inhibitor der menschlichen 7,8-Dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1) mit einem IC50-Wert von 0,8 nM. MTH1 hydrolysiert oxidierte Purin-Nukleosidtriphosphate, die andernfalls in die DNA/RNA eingebaut werden und zu DNA-Schäd
Storage
Lagerung bei -20°C
Verschickt in
Eistruhe + Eispads
Reinheit
≥98%
Namen und Kennungen
Pubchem Sid
504772332
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504772332
Kanonisches Lächeln
CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N
IUPAC Name
6-(2,3-dichlorophenyl)-4-N-methylpyrimidine-2,4-diamine
InChIKey
URWCXPXBBITYLR-UHFFFAOYSA-N
INCHI
1S/C11H10Cl2N4/c1-15-9-5-8(16-11(14)17-9)6-3-2-4-7(12)10(6)13/h2-5H,1H3,(H3,14,15,16,17)
Isomere SMILES
CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N
PubChem CID
73441664
Molekulargewicht
269.13

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
KlasseDiazines
SubclassPyrimidines and pyrimidine derivatives
Intermediate Tree Nodes Not available
Direct ParentPhenylpyrimidines
Alternative Parents Dichlorobenzenes  Aminopyrimidines and derivatives  Imidolactams  Aryl chlorides  Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents 4-phenylpyrimidine - 1,2-dichlorobenzene - Aminopyrimidine - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Imidolactam - Benzenoid - Heteroaromatic compound - Azacycle - Organohalogen compound - Hydrocarbon derivative - Organochloride - Organonitrogen compound - Amine - Primary amine - Organic nitrogen compound - Aromatic heteromonocyclic compound
BeschreibungThis compound belongs to the class of organic compounds known as phenylpyrimidines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrimidine ring through a CC or CN bond. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
External Descriptors Not available
3D-Struktur
Interaktives chemisches Strukturmodell





Zugehörige Ziele (menschlich)
NUDT1 Tchem 7,8-dihydro-8-oxoguanine triphosphatase (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MRC5 (9203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT4 (17854 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H358 (882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SW480 (6023 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BJ (6930 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMEC (560 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H460 (60772 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Zugehörige Ziele (nicht menschlich)
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver microsome (341 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDatumArtikel
E2622136Certificate of AnalysisMay 28, 2026 T305079
A2219597Certificate of AnalysisNov 04, 2024 T305079
A2219706Certificate of AnalysisNov 04, 2024 T305079
A2219708Certificate of AnalysisNov 04, 2024 T305079
A2219744Certificate of AnalysisNov 04, 2024 T305079
A2219745Certificate of AnalysisNov 04, 2024 T305079
A2219746Certificate of AnalysisNov 04, 2024 T305079
Chemische und physikalische Eigenschaften
Löslichkeit5 mg/mL, clear (warmed)
Molekulargewicht269.130 g/mol
XLogP33.100
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass268.028 Da
Monoisotopic Mass268.028 Da
Topological Polar Surface Area63.800 Ų
Heavy Atom Count17
Formal Charge0
Complexity254.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Lösungsrechner
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