≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
WAY-262611 WAY-262611 (BML-WN110, Compound 5) is a beta-catenin (β-Catenin) agonist that increases bone formation rate with EC50 of 0.63 μM in TCF-Luciferase assay. WAY-262611 is also an inhibitor of dickkopf 1 (DKK1) .
Targets
DKK1 ; β-Catenin (TCF-Luciferase assay) ; 0.63 μM(EC50)
In vitro
WAY-262611, the DKK1 inhibitor, blocks DKK1 and restores the GDF5 reduced MMP13 gene expression.
In vivo
WAY-262611 has excellent pharmacokinetic properties and shows a dose dependent increase in the trabecular bone formation rate in ovariectomized rats following oral administration.
Cell Research(from reference)
Cell lines：Surplus human chondrocytes
Concentrations：0.01 μM, 0.1 μM, 1 μM
Incubation Time：21 days
| Pubchem Sid | 504770015 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504770015 |
| Canonical Smiles | C1CN(CCC1CN)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3 |
| IUPAC Name | [1-(4-naphthalen-2-ylpyrimidin-2-yl)piperidin-4-yl]methanamine |
| InChIKey | QHLITPHIARVDJI-UHFFFAOYSA-N |
| INCHI | 1S/C20H22N4/c21-14-15-8-11-24(12-9-15)20-22-10-7-19(23-20)18-6-5-16-3-1-2-4-17(16)13-18/h1-7,10,13,15H,8-9,11-12,14,21H2 |
| Isomeric SMILES | C1CN(CCC1CN)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3 |
| PubChem CID | 25199517 |
| Molecular Weight | 318.42 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Naphthalenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Naphthalenes |
| Alternative Parents | Dialkylarylamines Aminopyrimidines and derivatives Piperidines Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Naphthalene - Dialkylarylamine - Aminopyrimidine - Piperidine - Pyrimidine - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Organic nitrogen compound - Primary amine - Amine - Organonitrogen compound - Organopnictogen compound - Primary aliphatic amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2306195 | Certificate of Analysis | Dec 12, 2025 | W414491 |
| C2306197 | Certificate of Analysis | Dec 12, 2025 | W414491 |
| C2306199 | Certificate of Analysis | Dec 12, 2025 | W414491 |
| C2306204 | Certificate of Analysis | Dec 12, 2025 | W414491 |
| C2306207 | Certificate of Analysis | Dec 12, 2025 | W414491 |
| C2306210 | Certificate of Analysis | Dec 12, 2025 | W414491 |
| C2303195 | Certificate of Analysis | Nov 07, 2022 | W414491 |
| I2523080 | Certificate of Analysis | Nov 07, 2022 | W414491 |
| Solubility | Solubility (25°C) In vitro DMSO: 64 mg/mL (200.99 mM); Water: 10 mg/mL (31.4 mM); Ethanol: 10 mg/mL (31.4 mM); |
|---|---|
| Molecular Weight | 318.400 g/mol |
| XLogP3 | 3.400 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 318.184 Da |
| Monoisotopic Mass | 318.184 Da |
| Topological Polar Surface Area | 55.000 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 393.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
