zidesamtinib - Moligand™ , Inhibitor of c-ros oncogene 1; receptor tyrosine kinase;Inhibitor of neurotrophic receptor tyrosine kinase 1, CAS No.Z614962, Inhibitor of c-ros oncogene 1; receptor tyrosine kinase;Inhibitor of neurotrophic receptor tyrosine kinase 1

CAS: Z614962 Cat. No.: Z614962 PubChem CID: 166560233

GRADE & PURITY Moligand™

Synonyms

Example 5 [US383715659] | SCHEMBL24007115 | EX-A8016 | NVL520 | NVL-520 | 2739829-00-4 | MX5KQV5XHC | Zidesamtinib | zidesamtinib [INN] | GTPL12392

Storage

Room temperature

Specifications

Synonyme

Example 5 [US383715659] | SCHEMBL24007115 | EX-A8016 | NVL520 | NVL-520 | 2739829-00-4 | MX5KQV5XHC | Zidesamtinib | zidesamtinib [INN] | GTPL12392

Spezifikationen & Reinheit

Moligand™

Storage

Room temperature

Note

Moligand™

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Inhibitor of c-ros oncogene 1; receptor tyrosine kinase;Inhibitor of neurotrophic receptor tyrosine kinase 1

Namen und Kennungen

• Kanonisches Lächeln: CCN1N=CC2=C1C3=CC(O[C@H](C)C4=CC(F)=CC=C4C5=NN(C)N=C5C2)=C(N)N=C3
• InChIKey: DTWUUAFTYSMNQX-GFCCVEGCSA-N
• INCHI: 1S/C22H22FN7O/c1-4-30-21-13(11-26-30)7-18-20(28-29(3)27-18)16-6-5-15(23)9-17(16)12(2)31-19-8-14(21)10-25-22(19)24/h5-6,8-12H,4,7H2,1-3H3,(H2,24,25)/t12-/m1/s1
• Isomere SMILES: CCN1C2=C(CC3=NN(N=C3C4=C(C=C(C=C4)F)[C@H](OC5=C(N=CC2=C5)N)C)C)C=N1
• PubChem CID: 166560233

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Diazines
      • Subclass Pyrimidines and pyrimidine derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Diazines
• Subclass: Pyrimidines and pyrimidine derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: O-alkylpyrimidines
• Alternative Parents: Polyhalopyridines Methylpyridines Alkyl aryl ethers 2-halopyridines Imidolactams Benzenoids Triazoles Heteroaromatic compounds Vinyl fluorides Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Hydrazones Fluoroalkenes Azacyclic compounds Aldimines Organopnictogen compounds Organofluorides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: O-alkylpyrimidine - Polyhalopyridine - 2-halopyridine - Methylpyridine - Alkyl aryl ether - Imidolactam - Benzenoid - Pyridine - Heteroaromatic compound - 1,2,3-triazole - Azole - Oxacycle - Azacycle - Fluoroalkene - Haloalkene - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Vinyl halide - Vinyl fluoride - Hydrazone - Ether - Aldimine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Primary aliphatic amine - Imine - Amine - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as o-alkylpyrimidines. These are compounds containing a pyrimidine , which is O-alkylated at one or more ring positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

ROS1 Tclin Proto-oncogene tyrosine-protein kinase ROS (0 Activities)

Discover Target: ROS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NTRK1 Tclin High affinity nerve growth factor receptor (0 Activities)

Discover Target: NTRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is Z614962. InChIKey DTWUUAFTYSMNQX-GFCCVEGCSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.