CaSR
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54 products
Popular Products
- NPS 2143 hydrochloride◐ .Made to order · 8–12 wks Item #: N275851View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile;hydrochloride
- SMILES
- CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl
- InChIKey
- ZEBNDUQLNGYBNL-VEIFNGETSA-N
- InChI
- show more
- Synonyms
- HY-10171 | 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile;hydrochlor...
- NPS-2143, Allosteric modulator of CaS receptor;Allosteric modulator of GPRC6 receptor;Allosteric modulator of mGlu 5 receptorCAS: 284035-33-2 Formula: C24H25ClN2O2 Molecular Weight: 408.93Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: N125903View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
- SMILES
- CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O
- InChIKey
- PZUJQWHTIRWCID-HXUWFJFHSA-N
- InChI
- 1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1
- Synonyms
- AC-26854 | GTPL716 | EX-A017 | L-Phe-OMe.HCl | SW219455-1 | BCP02421 | YP1 | 2-Chloro-6-[((2R)-3-([1,1-dimethyl-2-(2-...
- (S)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid◐ .Made to order · 8–12 wks Item #: T170295View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
- SMILES
- C1C(NCC2=C1C3=CC=CC=C3N2)C(=O)O
- InChIKey
- FSNCEEGOMTYXKY-JTQLQIEISA-N
- InChI
- 1S/C12H12N2O2/c15-12(16)10-5-8-7-3-1-2-4-9(7)14-11(8)6-13-10/h1-4,10,13-14H,5-6H2,(H,15,16)/t10-/m0/s1
- Synonyms
- H-Tpi-OH;L-1,2,3,4-Tetrahydro--carboline-3-carboxylic acid;L-Tryptoline-3-carboxylic acid;L-1,2,3,4-Tetrahydro-9H-pyr...
- NPS 2390, Allosteric modulator of mGlu 1 receptorCAS: 226878-01-9 Formula: C19H21N3O Molecular Weight: 307.39Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)● In Stock — US warehouse, ships to EU* Item #: N286666View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(1-adamantyl)quinoxaline-2-carboxamide
- SMILES
- C1C2CC3CC1CC(C2)(C3)NC(=O)C4=NC5=CC=CC=C5N=C4
- InChIKey
- ZKFVOZCCAXQXBU-UHFFFAOYSA-N
- InChI
- 1S/C19H21N3O/c23-18(17-11-20-15-3-1-2-4-16(15)21-17)22-19-8-12-5-13(9-19)7-14(6-12)10-19/h1-4,11-14H,5-10H2,(H,22,23)
- Synonyms
- ZKFVOZCCAXQXBU-UHFFFAOYSA-N | C19H21N3O | L000447 | N-340 | N-((3R,5R)-Adamantan-1-yl)quinoxaline-2-carboxamide | HY-...
- AC 265347, Allosteric modulator of CaS receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: A288466View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(1,3-benzothiazol-2-yl)-1-(2,4-dimethylphenyl)ethanol
- SMILES
- CC1=CC(=C(C=C1)C(C)(C2=NC3=CC=CC=C3S2)O)C
- InChIKey
- IGSZVEPQZANNAB-UHFFFAOYSA-N
- InChI
- 1S/C17H17NOS/c1-11-8-9-13(12(2)10-11)17(3,19)16-18-14-6-4-5-7-15(14)20-16/h4-10,19H,1-3H3
- Synonyms
- AC265347 | AC-265347 | SCHEMBL19462840 | AC-265347, >=98% (HPLC) | Q27074133 | 1-(Benzo[d]thiazol-2-yl)-1-(2,4-dimeth...
- R 568 hydrochloride, Calcium sensing receptor modulator● In Stock — US warehouse, ships to EU* Item #: R287293View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine;hydrochloride
- SMILES
- CC(C1=CC(=CC=C1)OC)NCCCC2=CC=CC=C2Cl.Cl
- InChIKey
- YJXUXANREVNZLH-PFEQFJNWSA-N
- InChI
- 1S/C18H22ClNO.ClH/c1-14(16-8-5-10-17(13-16)21-2)20-12-6-9-15-7-3-4-11-18(15)19;/h3-5,7-8,10-11,13-14,20H,6,9,12H2,1-2H3;1H/t14-;/m1./s1
- Synonyms
- 3-(2-Chlorophenyl)-N-((1R)-1-(3-methoxyphenyl)ethyl)propan-1-amine hydrochloride | Tecalcet hydrochloride | D06020 | ...
- Calindol hydrochlorideSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: C337240View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (1R)-N-(1H-indol-2-ylmethyl)-1-naphthalen-1-ylethanamine;hydrochloride
- SMILES
- CC(C1=CC=CC2=CC=CC=C21)NCC3=CC4=CC=CC=C4N3.Cl
- InChIKey
- KFILKQPBQZIRST-XFULWGLBSA-N
- InChI
- 1S/C21H20N2.ClH/c1-15(19-11-6-9-16-7-2-4-10-20(16)19)22-14-18-13-17-8-3-5-12-21(17)23-18;/h2-13,15,22-23H,14H2,1H3;1H/t15-;/m1./s1
- Synonyms
- (1R)-N-(1H-indol-2-ylmethyl)-1-naphthalen-1-ylethanamine;hydrochloride | (1R)-N-[(1H-Indol-2-yl)methyl]-1-(naphthalen...
- Calhex 231, Allosteric modulator of CaS receptorCAS: 652973-93-8 Formula: C25H27ClN2O Molecular Weight: 406.95Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: C275037View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-chloro-N-[(1S,2S)-2-[[(1R)-1-naphthalen-1-ylethyl]amino]cyclohexyl]benzamide
- SMILES
- CC(C1=CC=CC2=CC=CC=C21)NC3CCCCC3NC(=O)C4=CC=C(C=C4)Cl
- InChIKey
- YTFUQWWKTIWYEY-CQLNOVPUSA-N
- InChI
- show more
- Synonyms
- 4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide
- Calhex 231 hydrochloride◐ .Made to order · 8–12 wks Item #: C287996View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-chloro-N-[(1S,2S)-2-[[(1R)-1-naphthalen-1-ylethyl]amino]cyclohexyl]benzamide;hydrochloride
- SMILES
- CC(C1=CC=CC2=CC=CC=C21)NC3CCCCC3NC(=O)C4=CC=C(C=C4)Cl.Cl
- InChIKey
- KZPHZSFSFANQIS-GRFVZBLOSA-N
- InChI
- show more
- Synonyms
- 4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride
- Cinacalcet HCl, Calcium sensing receptor positive allosteric modulatorCAS: 364782-34-3 EC Number: 620-490-5 PubChem CID: 156418 Formula: C22H22F3N·HCl Molecular Weight: 393.87● In Stock — US warehouse, ships to EU* Item #: C129866View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
- SMILES
- CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
- InChIKey
- QANQWUQOEJZMLL-PKLMIRHRSA-N
- InChI
- 1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1
- Synonyms
- 1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride | CAS-364782-34-3 | ...
- LigustroflavoneCAS: 260413-62-5 Formula: C33H40O18 Molecular Weight: 724.6610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: L422913View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)OC6C(C(C(C(O6)C)O)O)O)O)O)O)O)O
- InChIKey
- NULBHTHMVOCGOE-ZBCCAYPVSA-N
- InChI
- show more
- Synonyms
- AKOS026674258 | 7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-...
- LigustroflavoneCAS: 260413-62-5 Formula: C33H40O18 Molecular Weight: 724.66● In Stock — US warehouse, ships to EU* Item #: L353963View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)OC6C(C(C(C(O6)C)O)O)O)O)O)O)O)O
- InChIKey
- NULBHTHMVOCGOE-ZBCCAYPVSA-N
- InChI
- show more
- Synonyms
- AKOS026674258 | 7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-...
![(S)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid](https://www.aladdinsci.com/media/catalog/product/cache/6360e336b2a70951114dbd37294096ee/T/1/T170295.jpg)
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the CaSR listing put together?
It draws on reported CaSR annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CaSR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CaSR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CaSR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CaSR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CaSR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CaSR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.