CaSR

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  1. SB-423557
    CAS: 351490-26-1 PubChem CID: 21950214
    ◐ .Made to order · 8–12 wks Item #: S1433466
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    IUPAC Name
    ethyl 3-[4-cyano-3-[3-[[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]phenyl]propanoate
    SMILES
    CCOC(=O)CCC1=CC(=C(C=C1)C#N)OCC(CNC(C)(C)CC2CC3=CC=CC=C3C2)O
    InChIKey
    DMWBVRRUBDZTBK-UHFFFAOYSA-N
    InChI
    1S/C28H36N2O4/c1-4-33-27(32)12-10-20-9-11-24(17-29)26(15-20)34-19-25(31)18-30-28(2,3)16-21-13-22-7-5-6-8-23(22)14-21/h5-9,11,15,21,25,30-31H,4,10,12-1show more
  2. Calhex 231 hydrochloride
    CAS: 2387505-78-2 PubChem CID: 11849513 Formula: C25H27ClN2O.HCl Molecular Weight: 443.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: C1493646
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  3. Calindol hydrochloride
    CAS: 729610-18-8 EC Number: 110-159-9 Formula: C21H21ClN2 Molecular Weight: 336.86
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: C1495468
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  4. Encaleret
    CAS: 787583-71-5 Formula: C29H33ClFNO4 Molecular Weight: 514.03
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: E1497016
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  5. GSK3004774
    CAS: 2138814-32-9 PubChem CID: 134817165 Formula: C32H40N4O3 Molecular Weight: 528.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: G1494021
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  6. Evocalcet
    CAS: 870964-67-3 EC Number: 887-622-3 PubChem CID: 71242808 Formula: C24H26N2O2 Molecular Weight: 374.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: E1498713
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the CaSR listing put together?
It draws on reported CaSR annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CaSR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CaSR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CaSR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CaSR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CaSR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CaSR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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