CaSR

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  1. Upacicalcet sodium
    CAS: 2052969-18-1 PubChem CID: 141719047 Formula: C11H13ClN3NaO6S Molecular Weight: 373.75
    ◐ .Made to order · 8–12 wks Item #: U646448
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    SMILES
    CC1=C(C=C(C=C1Cl)S(=O)(=O)[O-])NC(=O)NC[C@@H](C(=O)O)N.[Na+]
  2. Etelcalcetide hydrochloride (AMG 416 hydrochloride)
    CAS: 1334237-71-6 Formula: C38H73N21O10S2.17/2HCl Molecular Weight: 1353.33
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: E646830
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    IUPAC Name
    (2R)-3-[[(2S)-2-acetamido-3-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropashow more
    SMILES
    CC(C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CSSCC(C(=O)O)N)NC(=O)C.Cl
    InChIKey
    KHQMSZGKHGQUHG-WZDHWKSBSA-N
    InChI
    1S/C38H73N21O10S2.ClH/c1-18(28(62)56-22(27(40)61)8-4-12-49-35(41)42)53-30(64)23(9-5-13-50-36(43)44)58-32(66)25(11-7-15-52-38(47)48)59-31(65)24(10-6-14show more
    Synonyms
    ETELCALCETIDE HYDROCHLORIDE [MI] | SCHEMBL22578458 | etelcalcetide hydrochloride | KAI-4169 hydrochloride | Etelcalce...
  3. GSK3004774
    CAS: 2138814-32-9 PubChem CID: 134817165 Formula: C32H40N4O3 Molecular Weight: 528.69
    ◐ .Made to order · 8–12 wks Item #: G650538
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    IUPAC Name
    1-[3-[[4-[(3R)-3-[[(1S)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]benzoyl]amino]propyl]piperidine-4-carboxylic acid
    SMILES
    CC(C1=CC=CC2=CC=CC=C21)NC3CCN(C3)C4=CC=C(C=C4)C(=O)NCCCN5CCC(CC5)C(=O)O
    InChIKey
    HBTVUVNVTSSIHP-WNCULLNHSA-N
    InChI
    1S/C32H40N4O3/c1-23(29-9-4-7-24-6-2-3-8-30(24)29)34-27-16-21-36(22-27)28-12-10-25(11-13-28)31(37)33-17-5-18-35-19-14-26(15-20-35)32(38)39/h2-4,6-13,23show more
  4. SB-423562
    CAS: 351490-27-2 Formula: C26H32N2O4 Molecular Weight: 436.54
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: S651271
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    IUPAC Name
    3-[4-cyano-3-[(2R)-3-[[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]phenyl]propanoic acid
    SMILES
    CC(C)(CC1CC2=CC=CC=C2C1)NCC(COC3=C(C=CC(=C3)CCC(=O)O)C#N)O
    InChIKey
    NJBFJCJKWWIKRD-HSZRJFAPSA-N
    InChI
    1S/C26H32N2O4/c1-26(2,14-19-11-20-5-3-4-6-21(20)12-19)28-16-23(29)17-32-24-13-18(8-10-25(30)31)7-9-22(24)15-27/h3-7,9,13,19,23,28-29H,8,10-12,14,16-17show more
    Synonyms
    3-[4-cyano-3-[(2R)-3-[[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]phenyl]propanoic aci...
  5. Poly-D-lysine hydrobromide
    CAS: 27964-99-4 PubChem CID: 87493163 Formula: D-Lys-(D-Lys)n-D-Lys·xHBr
    Solid BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. γ-irradiated ? Gamma-irradiated — sterilized by gamma radiation for assured sterility. Use for single-use bioprocess and culture items needing terminal sterilization. average mol wt 30,000-70,000, lyophilized powder
    ◐ .Made to order · 8–12 wks Item #: P755746
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    IUPAC Name
    (2R)-2,6-diaminohexanoic acid;hydrobromide
    SMILES
    C(CCN)CC(C(=O)O)N.Br
    InChIKey
    MEXAGTSTSPYCEP-NUBCRITNSA-N
    InChI
    1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m1./s1
  6. Poly-D-lysine hydrobromide
    CAS: 27964-99-4 EC Number: 959-037-4 PubChem CID: 87493163 Formula: D-Lys-(D-Lys)n-D-Lys·xHBr
    Solid BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. γ-irradiated ? Gamma-irradiated — sterilized by gamma radiation for assured sterility. Use for single-use bioprocess and culture items needing terminal sterilization. mol wt ≥300,000, lyophilized powder
    ◐ .Made to order · 8–12 wks Item #: P755729
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    IUPAC Name
    (2R)-2,6-diaminohexanoic acid;hydrobromide
    SMILES
    C(CCN)CC(C(=O)O)N.Br
    InChIKey
    MEXAGTSTSPYCEP-NUBCRITNSA-N
    InChI
    1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m1./s1
  7. Ronacaleret Hydrochloride
    CAS: 702686-96-2 Formula: C25H32ClF2NO4 Molecular Weight: 484
    ◐ .Made to order · 8–12 wks Item #: R1315946
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    Technical Identifiers
    IUPAC Name
    3-[3-[(2R)-3-[[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]-4,5-difluorophenyl]propanoic acid;hydrochloride
    SMILES
    CC(C)(CC1CC2=CC=CC=C2C1)NC[C@H](COC3=C(C(=CC(=C3)CCC(=O)O)F)F)O.Cl
    InChIKey
    BQGSCEAKPBWIDI-VEIFNGETSA-N
    InChI
    1S/C25H31F2NO4.ClH/c1-25(2,13-17-9-18-5-3-4-6-19(18)10-17)28-14-20(29)15-32-22-12-16(7-8-23(30)31)11-21(26)24(22)27;/h3-6,11-12,17,20,28-29H,7-10,13-1show more
  8. L-γ-glutamyl-L-valine
    CAS: 2746-34-1 Formula: C10H18N2O5 Molecular Weight: 246.26
    Solid ≥99%
    ◐ .Made to order · 8–12 wks Item #: G1046299
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    IUPAC Name
    (2S)-2-amino-5-[[(1S)-1-carboxy-2-methylpropyl]amino]-5-oxopentanoic acid
    SMILES
    CC(C)C(C(=O)O)NC(=O)CCC(C(=O)O)N
    InChIKey
    AQAKHZVPOOGUCK-XPUUQOCRSA-N
    InChI
    1S/C10H18N2O5/c1-5(2)8(10(16)17)12-7(13)4-3-6(11)9(14)15/h5-6,8H,3-4,11H2,1-2H3,(H,12,13)(H,14,15)(H,16,17)/t6-,8-/m0/s1
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the CaSR listing put together?
It draws on reported CaSR annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CaSR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CaSR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CaSR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CaSR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CaSR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CaSR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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