c-Kit

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  1. Velzatinib(M4205)
    CAS: 2590556-80-0 PubChem CID: 155587867 Formula: C29H32N8O Molecular Weight: 508.62
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: M650715
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    IUPAC Name
    N-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine
    SMILES
    CN1C=C(C=N1)C2=CC=C(C=C2)CNC3=NC=NC(=C3)C4=CN=C5N4C=CC(=C5)OCCCN6CCCC6
    InChIKey
    LVMAULGVWBINFP-UHFFFAOYSA-N
    InChI
    1S/C29H32N8O/c1-35-20-24(18-34-35)23-7-5-22(6-8-23)17-30-28-16-26(32-21-33-28)27-19-31-29-15-25(9-13-37(27)29)38-14-4-12-36-10-2-3-11-36/h5-9,13,15-16show more
    Synonyms
    [4-(Methyl-1H-pyrazol-4-yl)-benzyl] -(6-[7-(3-pyrrolidin-1-yl-propoxy)-imidazo[1,2-a] pyridin-3-yl]-pyrimidin-4-yl]-a...
  2. SU14813 maleate
    CAS: 849643-15-8 PubChem CID: 11353475 Formula: C27H31FN4O8 Molecular Weight: 558.56
    ◐ .Made to order · 8–12 wks Item #: S650731
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    SMILES
    CC1=C(NC(=C1C(=O)NC[C@@H](CN2CCOCC2)O)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O.C(=C\C(=O)O)\C(=O)O
  3. Dovitinib lactate
    CAS: 692737-80-7 PubChem CID: 135431668 Formula: C24H27FN6O4 Molecular Weight: 482.52
    ◐ .Made to order · 8–12 wks Item #: D651722
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    IUPAC Name
    4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one;2-hydroxypropanoic acid
    SMILES
    CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N
    InChIKey
    ZRHDKBOBHHFLBW-UHFFFAOYSA-N
    InChI
    1S/C21H21FN6O.C3H6O3/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29;1-2(4)3(5)6/h2-6,11H,7-10H2,1H3,(H,show more
    Synonyms
    BCP04112 | Triptorelin (USAN/INN) | TKI258 | 4-AMINO-5-FLUORO-3-(6-(4-METHYLPIPERAZIN-1-YL)-1H-BENZO-[D]IMIDAZOL-2-YL...
  4. 3-[2-(2-Cyclopentyl-6-{[4-(dimethylphosphoryl)phenyl]amino}-9H-purin-9-YL)ethyl]phenol
    CAS: 845895-51-4 PubChem CID: 9934643 Formula: C26H30N5O2P Molecular Weight: 475.5
    ◐ .Made to order · 8–12 wks Item #: C669044
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    IUPAC Name
    3-[2-[2-cyclopentyl-6-(4-dimethylphosphorylanilino)purin-9-yl]ethyl]phenol
    SMILES
    CP(=O)(C)C1=CC=C(C=C1)NC2=C3C(=NC(=N2)C4CCCC4)N(C=N3)CCC5=CC(=CC=C5)O
    InChIKey
    VVOYROSONSLQQK-UHFFFAOYSA-N
    InChI
    1S/C26H30N5O2P/c1-34(2,33)22-12-10-20(11-13-22)28-25-23-26(30-24(29-25)19-7-3-4-8-19)31(17-27-23)15-14-18-6-5-9-21(32)16-18/h5-6,9-13,16-17,19,32H,3-4show more
    Synonyms
    AP-23464 | AP23464 | HEJ6QDU4PA | UNII-HEJ6QDU4PA | 3-[2-(2-CYCLOPENTYL-6-{[4-(DIMETHYLPHOSPHORYL)PHENYL]AMINO}-9H-PU...
  5. Barzolvolimab (anti-c-Kit)
    CAS: 2438203-51-9
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab182977
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    Technical Identifiers
    Associated targets
    KIT
    Short Overview
    Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    [Barzolvolimab]
    Synonyms
    C Kit antibody | c-Kit antibody | c-Kit Ligand antibody | CD117 antibody | Kit antibody | Kit Ligand antibody | KIT o...
  6. CGP 41251
    CAS: 120685-11-2 EC Number: 848-383-0 PubChem CID: 9829523 Formula: C35H30N4O4 Molecular Weight: 570.64
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: C769921
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    Technical Identifiers
    IUPAC Name
    N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25show more
    SMILES
    CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
    InChIKey
    BMGQWWVMWDBQGC-IIFHNQTCSA-N
    InChI
    1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(show more
    Synonyms
    PKC412 | N-Benzoylstaurosporine | CGP41231
  7. 3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
    CAS: 1258391-13-7 Formula: C31H31F3N6O2S Molecular Weight: 608.7
    ◐ .Made to order · 8–12 wks Item #: C1275678
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    Technical Identifiers
    IUPAC Name
    3-[2-(cyclopropanecarbonylamino)-[1,3]thiazolo[5,4-b]pyridin-5-yl]-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC=CC(=C3)C4=NC5=C(C=C4)N=C(S5)NC(=O)C6CC6)C(F)(F)F
    InChIKey
    VTWWRKFUHCSCEW-UHFFFAOYSA-N
    InChI
    1S/C31H31F3N6O2S/c1-2-39-12-14-40(15-13-39)18-22-8-9-23(17-24(22)31(32,33)34)35-28(42)21-5-3-4-20(16-21)25-10-11-26-29(36-25)43-30(37-26)38-27(41)19-6show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for c-Kit?
Compounds associated with c-Kit are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does c-Kit sit within Protein Tyrosine Kinase/RTK?
c-Kit is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from c-Kit?
For compounds listed under c-Kit, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for c-Kit?
Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring c-Kit, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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