Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- Ruxolitinib (INCB018424)CAS: 941678-49-5 EC Number: 107-728-9 PubChem CID: 25126798 Formula: C17H18N6 Molecular Weight: 306.37Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: R126338View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
- SMILES
- C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
- InChIKey
- HFNKQEVNSGCOJV-OAHLLOKOSA-N
- InChI
- 1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
- Synonyms
- INCB 018424 | INCB018424 | INCB-018424 | (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-p...
- STA-21 (Ochromycinone)CAS: 28882-53-3 Formula: C19H14O4 Molecular Weight: 306.31◐ .Made to order · 8–12 wks Item #: S276114View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3S)-8-hydroxy-3-methyl-3,4-dihydro-2H-benzo[a]anthracene-1,7,12-trione
- SMILES
- CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O
- InChIKey
- ZAWXOCUFQSQDJS-VIFPVBQESA-N
- InChI
- 1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3/t9-/m0/s1
- Synonyms
- AKOS030254378 | J-017311 | C90290 | CKZ6P7I25M | MEGxm0_000296 | HY-121482 | Benz[a]anthracene-1,7,12(2H)-trione, 3,4...
- Glycodeoxycholic acid monohydrateSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: G113438View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC(CCC(=O)NCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C
- InChIKey
- WVULKSPCQVQLCU-BUXLTGKBSA-N
- InChI
- show more
- Synonyms
- GLYCODEOXYCHOLIC_ACID | F20550 | N-((3-alpha,5-beta,12-alpha)-3,12-Dihydroxy-24-oxocholan-24-yl)-glycine | Spectrum5_...
- AlantolactoneCAS: 546-43-0 Formula: C15H20O2 Molecular Weight: 232.32Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥97%(HPLC)● In Stock — US warehouse, ships to EU* Item #: A114070View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one
- SMILES
- CC1CCCC2(C1=CC3C(C2)OC(=O)C3=C)C
- InChIKey
- PXOYOCNNSUAQNS-AGNJHWRGSA-N
- InChI
- 1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
- Synonyms
- (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one | Q21099633 | DT...
- PF 06551600 malonate◐ .Made to order · 8–12 wks Item #: P288768View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one;propanedioic acid
- SMILES
- CC1CCC(CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3.C(C(=O)O)C(=O)O
- InChIKey
- QMPMPSGDPRHZCG-VZXYPILPSA-N
- InChI
- show more
- Synonyms
- Ritlecitinib malonate | 132LF5WGH4 | PF 06651600 malonate - Bio-X | PF-06651600 malonate | PF 06551600 malonate | 1-[...
- ScutellarinCAS: 27740-01-8 Formula: C21H18O12 Molecular Weight: 462.37Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.● In Stock — US warehouse, ships to EU* Item #: S107670View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S,3S,4S,5R,6S)-6-[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
- SMILES
- C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O)O
- InChIKey
- DJSISFGPUUYILV-ZFORQUDYSA-N
- InChI
- show more
- Synonyms
- CHEBI:61278 | DTXSID101336184 | Scutellarein 7-glucuronide | BDA54172 | S-7-G | Scutellarein 7-beta-D-glucuronide | S...
- HJC0152● In Stock — US warehouse, ships to EU* Item #: H302847View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-(2-aminoethoxy)-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide;hydrochloride
- SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)OCCN.Cl
- InChIKey
- XRZHLOYBZOONSZ-UHFFFAOYSA-N
- InChI
- 1S/C15H13Cl2N3O4.ClH/c16-9-1-4-14(24-6-5-18)11(7-9)15(21)19-13-3-2-10(20(22)23)8-12(13)17;/h1-4,7-8H,5-6,18H2,(H,19,21);1H
- GYY 4137CAS: 106740-09-4 Formula: C11H16NO2PS2·C4H9NO Molecular Weight: 376.47Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● In Stock — US warehouse, ships to EU* Item #: G275260View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (4-methoxyphenyl)-morpholin-4-yl-sulfanyl-sulfanylidene-λ5-phosphane;morpholine
- SMILES
- COC1=CC=C(C=C1)P(=S)(N2CCOCC2)S.C1COCCN1
- InChIKey
- YZMHNNLDUWRZFW-UHFFFAOYSA-N
- InChI
- 1S/C11H16NO2PS2.C4H9NO/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;1-3-6-4-2-5-1/h2-5H,6-9H2,1H3,(H,16,17);5H,1-4H2
- Synonyms
- BCP23715 | Morpholine (4-methoxyphenyl)(morpholino)phosphinodithioate | (4-Methoxyphenyl)morpholino-phosphinodithioic...
- HS-10296CAS: 1899921-05-1 Formula: C30H35N7O2 Molecular Weight: 525.64Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● In Stock — US warehouse, ships to EU* Item #: H305277View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide
- SMILES
- CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OC
- InChIKey
- DOEOECWDNSEFDN-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 1899921-05-1 | Egfr T790M inhibitor HS-10296 | HS10296 | HS-10296 | N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]...
- Gefitinib (ZD1839), Epidermal growth factor receptor erbB1 inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: G125799View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
- InChIKey
- XGALLCVXEZPNRQ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- ZD 1839 | AM20090619 | Gefitinib [USAN:INN:BAN] | SY017890 | CHEBI:49668 | nchembio866-comp14 | 4-(3'-Chloro-4'-fluor...
- HS-10296, Epidermal growth factor receptor erbB1 inhibitorCAS: 1899921-05-1 Formula: C30H35N7O2 Molecular Weight: 525.64Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: H305278View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide
- SMILES
- CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OC
- InChIKey
- DOEOECWDNSEFDN-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 1899921-05-1 | Egfr T790M inhibitor HS-10296 | HS10296 | HS-10296 | N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]...
- Gefitinib-based PROTAC 3Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: G287801View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCOCCOCCCCCOC4=C(C=C5C(=C4)C(=NC=N5)NC6=CC(=C(C=C6)F)Cl)OC)O
- InChIKey
- NICKHWYZMNLEPJ-TZSMONEZSA-N
- InChI
- show more
- Synonyms
- Gefitinib-based Proteolysis-targeting Chimera 3 | Iressa-based PROTAC 3 | (2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-Chloro-4...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].