🌎 Ship to: United States
Toggle Nav
Cart
Search
Same-day shipping on all in-stock items.
Advanced Search
Quick Order SDS / CoA Structure Bulk & Custom
Menu
Account
Settings
྾
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items

JAK/STAT Signaling

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.

1,726 products
Browse by Type Browse All Products
Shop by category

EGFR

852

Explore EGFR →

JAK

448

Explore JAK →

Pim

83

Explore Pim →

STAT

418

Explore STAT →

Popular Products

View as List Grid

Showing 205-216 of 1,726

Set Descending Direction
  1. 3-(4-Isopropylbenzylidenyl)­indolin-2-one(SU-4313)
    Wish List Compare
    3-(4-Isopropylbenzylidenyl)­indolin-2-one(SU-4313)
    CAS: 186611-55-2 Formula: C18H17NO Molecular Weight: 263.33
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: I337822
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (3E)-3-[(4-propan-2-ylphenyl)methylidene]-1H-indol-2-one
    SMILES
    CC(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O
    InChIKey
    IRQQWCZKCUQNSO-LFIBNONCSA-N
    InChI
    1S/C18H17NO/c1-12(2)14-9-7-13(8-10-14)11-16-15-5-3-4-6-17(15)19-18(16)20/h3-12H,1-2H3,(H,19,20)/b16-11+
    Synonyms
    SU-4313 | SU 4313 | 3-(4-Isopropylbenzylidene)indolin-2-one
  2. AG 1406 - ≥98% CAS No(71308-34-4) by Aladdin Scientific
    Wish List Compare
    AG 1406
    CAS: 71308-34-4 Formula: C16H18N2O Molecular Weight: 254.33
    ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A412268
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile
    SMILES
    CC(C)C1=CC(=CC(=C1O)C(C)C)C=C(C#N)C#N
    InChIKey
    JSDJFOADLLJFQX-UHFFFAOYSA-N
    InChI
    1S/C16H18N2O/c1-10(2)14-6-12(5-13(8-17)9-18)7-15(11(3)4)16(14)19/h5-7,10-11,19H,1-4H3
    Synonyms
    71308-34-4|Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-|AG 1406|AG1406|2-[[4-hydroxy-3,5-di...
  3. AG 43
    Wish List Compare
    AG 43
    CAS: 5553-97-9 Formula: C10H8N2O Molecular Weight: 172.18
    ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: A336632
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[(4-hydroxyphenyl)methyl]propanedinitrile
    SMILES
    C1=CC(=CC=C1CC(C#N)C#N)O
    InChIKey
    PDRLQWJJFLVIRC-UHFFFAOYSA-N
    InChI
    1S/C10H8N2O/c11-6-9(7-12)5-8-1-3-10(13)4-2-8/h1-4,9,13H,5H2
    Synonyms
    Tyrphostin A63 | 2-(4-hydroxybenzyl)malononitrile | 2-[(4-hydroxyphenyl)methyl]propanedinitrile
  4. AG 555 (Tyrphostin B46)
    Wish List Compare
    AG 555 (Tyrphostin B46)
    CAS: 133550-34-2 Formula: C19H18N2O3 Molecular Weight: 322.36
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A421271
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide
    SMILES
    C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
    InChIKey
    GSQOBTOAOGXIFL-LFIBNONCSA-N
    InChI
    1S/C19H18N2O3/c20-13-16(11-15-8-9-17(22)18(23)12-15)19(24)21-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,22-23H,4,7,10H2,(H,21,24)/b16-11+
    Synonyms
    NCGC00016028-05 | Tyrphostin deriv. 46 | J-006402 | 2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-...
  5. AG 99
    Wish List Compare
    AG 99
    CAS: 122520-85-8 EC Number: 878-366-3 Formula: C10H8N2O3 Molecular Weight: 204.18
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A420966
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
    SMILES
    C1=CC(=C(C=C1C=C(C#N)C(=O)N)O)O
    InChIKey
    USOXQZNJFMKTKJ-XVNBXDOJSA-N
    InChI
    1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+
    Synonyms
    Tyrphostin A46|AG 99|122520-85-8|Tyrphostin 46|118409-59-9|Tyrphostin AG 99|AG-99|(E)-2-cyano-3-(3,4-dihydroxyphenyl)...
  6. AG-1557
    Wish List Compare
    AG-1557
    CAS: 189290-58-2 Formula: C16H14IN3O2 Molecular Weight: 407.21
    ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A412206
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)I)OC
    InChIKey
    FGCLAQLIXMAIHT-UHFFFAOYSA-N
    InChI
    1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
    Synonyms
    4-Quinazolinamine, N-(3-iodophenyl)-6,7-dimethoxy- | MFCD28902185 | N-(3-Iodophenyl)-6,7-dimethoxy-4-quinazolinamine ...
  7. AG-1557
    Wish List Compare
    AG-1557
    CAS: 189290-58-2 Formula: C16H14IN3O2 Molecular Weight: 407.21
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A422322
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)I)OC
    InChIKey
    FGCLAQLIXMAIHT-UHFFFAOYSA-N
    InChI
    1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
    Synonyms
    4-Quinazolinamine, N-(3-iodophenyl)-6,7-dimethoxy- | MFCD28902185 | N-(3-Iodophenyl)-6,7-dimethoxy-4-quinazolinamine ...
  8. AKK1-IN-1
    Wish List Compare
    AKK1-IN-1
    CAS: 1093222-27-5 Formula: C20H13N5O Molecular Weight: 339.35
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A412377
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide
    SMILES
    C1=CC(=CN=C1)C(=O)NC2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)C#N
    InChIKey
    JTSLALYXYSRPGW-UHFFFAOYSA-N
    InChI
    1S/C20H13N5O/c21-9-13-3-5-14(6-4-13)16-8-17-18(12-24-19(17)23-11-16)25-20(26)15-2-1-7-22-10-15/h1-8,10-12H,(H,23,24)(H,25,26)
    Synonyms
    LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275 | A927453 | Pim1/AKK1-IN-1 | Q27462573 | F83701 | N-[5-(4-cyano...
  9. AMG-47a - ≥98% CAS No(882663-88-9) by Aladdin Scientific
    Wish List Compare
    AMG-47a
    CAS: 882663-88-9 Formula: C29H28F3N5O2 Molecular Weight: 535.56
    ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A412774
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    4-methyl-3-[2-(2-morpholin-4-ylethylamino)quinazolin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5
    InChIKey
    DVRSTRMZTAPMKO-UHFFFAOYSA-N
    InChI
    1S/C29H28F3N5O2/c1-19-5-6-21(27(38)35-24-4-2-3-23(17-24)29(30,31)32)16-25(19)20-7-8-26-22(15-20)18-34-28(36-26)33-9-10-37-11-13-39-14-12-37/h2-8,15-18show more
    Synonyms
    4-methyl-3-[2-(2-morpholin-4-ylethylamino)quinazolin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide | BCP01962 | BCPP00...
  10. AMG-47a
    Wish List Compare
    AMG-47a
    CAS: 882663-88-9 Formula: C29H28F3N5O2 Molecular Weight: 535.56
    2mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A426670
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    4-methyl-3-[2-(2-morpholin-4-ylethylamino)quinazolin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5
    InChIKey
    DVRSTRMZTAPMKO-UHFFFAOYSA-N
    InChI
    1S/C29H28F3N5O2/c1-19-5-6-21(27(38)35-24-4-2-3-23(17-24)29(30,31)32)16-25(19)20-7-8-26-22(15-20)18-34-28(36-26)33-9-10-37-11-13-39-14-12-37/h2-8,15-18show more
    Synonyms
    AMG-47a|882663-88-9|4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide|4...
  11. ASP3026, ALK tyrosine kinase receptor inhibitor
    Wish List Compare
    ASP3026, ALK tyrosine kinase receptor inhibitor
    CAS: 1097917-15-1 Formula: C29H40N8O3S Molecular Weight: 580.74
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A420576
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
    SMILES
    CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=N2)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
    InChIKey
    MGGBYMDAPCCKCT-UHFFFAOYSA-N
    InChI
    1S/C29H40N8O3S/c1-21(2)41(38,39)27-8-6-5-7-25(27)33-29-31-20-30-28(34-29)32-24-10-9-23(19-26(24)40-4)36-13-11-22(12-14-36)37-17-15-35(3)16-18-37/h5-10show more
    Synonyms
    F6O | SMR004702945 | UNII-HP4L6MXF10 | XTB91715 | NCGC00345791-01 | N2-(2-(isopropylsulfonyl)phenyl)-N4-(2-methoxy-4-...
  12. AS1517499
    Wish List Compare
    AS1517499
    CAS: 919486-40-1 Formula: C20H20ClN5O2 Molecular Weight: 397.86
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A426928
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    4-(benzylamino)-2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidine-5-carboxamide
    SMILES
    C1=CC=C(C=C1)CNC2=NC(=NC=C2C(=O)N)NCCC3=CC(=C(C=C3)O)Cl
    InChIKey
    OZRMEKAUZBKTTC-UHFFFAOYSA-N
    InChI
    1S/C20H20ClN5O2/c21-16-10-13(6-7-17(16)27)8-9-23-20-25-12-15(18(22)28)19(26-20)24-11-14-4-2-1-3-5-14/h1-7,10,12,27H,8-9,11H2,(H2,22,28)(H2,23,24,25,26show more
    Synonyms
    919486-40-1|AS-1517499|AS1517499|4-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide|4-(be...
Page
per page
🚚
Fast Shipping Same-day shipping on in-stock items
📋
Technical Details Quality & specification info on every product page
📦
Pack Size Options Multiple packaging sizes with pricing access from listing
🔬
R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].
JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.