JAK/STAT Signaling

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

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  1. Corosolic acid
    CAS: 4547-24-4 Formula: C30H48O4 Molecular Weight: 472.70
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: D135631
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    IUPAC Name
    (1S,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-piceshow more
    SMILES
    CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1C)C)C(=O)O
    InChIKey
    HFGSQOYIOKBQOW-ZSDYHTTISA-N
    InChI
    1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,show more
    Synonyms
    BENZYL5-AMINOPYRAZOLE-4-CARBOXYLATE | Corosolic acid, analytical standard | Corosolic acid, United States Pharmacopei...
  2. Delphinidin 3-β-D-Glucoside
    CAS: 6906-38-3 Formula: C21H21ClO12 Molecular Weight: 500.84
    ● In Stock — US warehouse, ships to EU* Item #: D136705
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    IUPAC Name
    (2S,3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chromenylium-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;chloride
    SMILES
    C1=C(C=C(C(=C1O)O)O)C2=[O+]C3=CC(=CC(=C3C=C2OC4C(C(C(C(O4)CO)O)O)O)O)O.[Cl-]
    InChIKey
    ZJWIIMLSNZOCBP-BTTVDUMLSA-N
    InChI
    1S/C21H20O12.ClH/c22-6-15-17(28)18(29)19(30)21(33-15)32-14-5-9-10(24)3-8(23)4-13(9)31-20(14)7-1-11(25)16(27)12(26)2-7;/h1-5,15,17-19,21-22,28-30H,6H2,show more
    Synonyms
    Delphinidin 3-O-beta-D-glucoside chloride | Delphinidin 3-O-beta-D-glucopyranoside | HY-108052 | Delphinidin 3-O-beta...
  3. Fraxinellone
    CAS: 28808-62-0 EC Number: 683-158-9 Formula: C14H16O3 Molecular Weight: 232.28
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: F405738
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    IUPAC Name
    (3R,3aR)-3-(furan-3-yl)-3a,7-dimethyl-3,4,5,6-tetrahydro-2-benzofuran-1-one
    SMILES
    CC1=C2C(=O)OC(C2(CCC1)C)C3=COC=C3
    InChIKey
    XYYAFLHHHZVPRN-GXTWGEPZSA-N
    InChI
    1S/C14H16O3/c1-9-4-3-6-14(2)11(9)13(15)17-12(14)10-5-7-16-8-10/h5,7-8,12H,3-4,6H2,1-2H3/t12-,14+/m0/s1
    Synonyms
    (3R,3aR)-3-(uran-3-yl)-3a,7-dimethyl-3,4,5,6-tetrahydro-2-benzouran-1-one | F1187 | NCI60_012928 | 4-(m-chlorophenyl)...
  4. WHI-P180 Hydrochloride
    CAS: 153437-55-9 PubChem CID: 53324500 Formula: C16H15N3O3·HCl Molecular Weight: 333.77
    ● In Stock — US warehouse, ships to EU* Item #: W404124
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    IUPAC Name
    3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol;hydrochloride
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC.Cl
    InChIKey
    MJLLZROGIFJFJJ-UHFFFAOYSA-N
    InChI
    1S/C16H15N3O3.ClH/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10;/h3-9,20H,1-2H3,(H,17,18,19);1H
    Synonyms
    3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol Hydrochloride | 3-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol Hydrochlo...
  5. khellin
    CAS: 82-02-0 EC Number: 201-392-8 Formula: C14H12O5 Molecular Weight: 260.25
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ◐ .Made to order · 8–12 wks Item #: K136893
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    IUPAC Name
    4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one
    SMILES
    CC1=CC(=O)C2=C(C3=C(C(=C2O1)OC)OC=C3)OC
    InChIKey
    HSMPDPBYAYSOBC-UHFFFAOYSA-N
    InChI
    1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3
    Synonyms
    Coronin | Kellina | Kelourin | Opera_ID_372 | Visnagalin | 4,8-dioxabenz-[f]indene | DTXCID7025267 | kelina | Viscard...
  6. (Rac)-JBJ-04-125-02
    CAS: 2140807-05-0 PubChem CID: 132020316 Formula: C29H26FN5O3S Molecular Weight: 543.61
    10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: R422587
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    IUPAC Name
    2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
    SMILES
    C1CN(CCN1)C2=CC=C(C=C2)C3=CC4=C(CN(C4=O)C(C5=C(C=CC(=C5)F)O)C(=O)NC6=NC=CS6)C=C3
    InChIKey
    VHQVOTINPRYDAO-UHFFFAOYSA-N
    InChI
    1S/C29H26FN5O3S/c30-21-5-8-25(36)24(16-21)26(27(37)33-29-32-11-14-39-29)35-17-20-2-1-19(15-23(20)28(35)38)18-3-6-22(7-4-18)34-12-9-31-10-13-34/h1-8,11show more
    Synonyms
    JBJ-04-125-02 racemate2H-​Isoindole-​2-​acetamide,α-​(5-​fluoro-​2-​hydroxyphenyl)​-​1,​3-​dihydro-​1-​oxo-​6-​[4-​(1-�...
  7. (Rac)-JBJ-04-125-02
    CAS: 2140807-05-0 PubChem CID: 132020316 Formula: C29H26FN5O3S Molecular Weight: 543.61
    ◐ .Made to order · 8–12 wks Item #: R414269
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    Technical Identifiers
    IUPAC Name
    2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
    SMILES
    C1CN(CCN1)C2=CC=C(C=C2)C3=CC4=C(CN(C4=O)C(C5=C(C=CC(=C5)F)O)C(=O)NC6=NC=CS6)C=C3
    InChIKey
    VHQVOTINPRYDAO-UHFFFAOYSA-N
    InChI
    1S/C29H26FN5O3S/c30-21-5-8-25(36)24(16-21)26(27(37)33-29-32-11-14-39-29)35-17-20-2-1-19(15-23(20)28(35)38)18-3-6-22(7-4-18)34-12-9-31-10-13-34/h1-8,11show more
    Synonyms
    JBJ-04-125-02 racemate2H-​Isoindole-​2-​acetamide,α-​(5-​fluoro-​2-​hydroxyphenyl)​-​1,​3-​dihydro-​1-​oxo-​6-​[4-​(1-�...
  8. 1,2,3,4,5,6-Hexabromocyclohexane
    CAS: 1837-91-8 EC Number: 679-897-1 Formula: C6H6Br6 Molecular Weight: 557.54
    2mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: H422255
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    IUPAC Name
    1,2,3,4,5,6-hexabromocyclohexane
    SMILES
    C1(C(C(C(C(C1Br)Br)Br)Br)Br)Br
    InChIKey
    QFQZKISCBJKVHI-UHFFFAOYSA-N
    InChI
    1S/C6H6Br6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H
    Synonyms
    1,2,3,4,5,6-Hexabrom-cyclohexan (I(2)-Form) | NSC-41797 | Benzene hexabromide | JAK2 Inhibitor II - CAS 1837-91-8 | s...
  9. 1,2,3,4-Tetrahydrostaurosporine
    CAS: 220038-19-7 PubChem CID: 4369398 Formula: C28H30N4O3 Molecular Weight: 470.6
    ◐ .Made to order · 8–12 wks Item #: T276512
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    IUPAC Name
    (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),14,19,21,2show more
    SMILES
    CC12C(C(CC(O1)N3C4=C(CCCC4)C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
    InChIKey
    KIZWKTROWIIMNN-FYTWVXJKSA-N
    InChI
    1S/C28H30N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h5,7,9,11,17,20show more
    Synonyms
    1,2,3,4-TETRAHYDROGEN-STAUROSPORINE | AFN 941 | Q27454934 | (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1...
  10. 1-(2-Bromoisovaleryl)urea
    CAS: 496-67-3 EC Number: 207-825-7 Formula: C6H11BrN2O2 Molecular Weight: 223.07
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B424280
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    IUPAC Name
    2-bromo-N-carbamoyl-3-methylbutanamide
    SMILES
    CC(C)C(C(=O)NC(=O)N)Br
    InChIKey
    CMCCHHWTTBEZNM-UHFFFAOYSA-N
    InChI
    1S/C6H11BrN2O2/c1-3(2)4(7)5(10)9-6(8)11/h3-4H,1-2H3,(H3,8,9,10,11)
    Synonyms
    BROMISOVAL [WHO-DD] | Bromisoval [INN] | Bromovaluree | GS-3579 | AB01316119-02 | Bromcarbamide | Bromovalerylurea (J...
  11. 1,8-Dihydroxy-3-methylanthraquinone
    CAS: 481-74-3 EC Number: 207-572-2 Formula: C15H10O4 Molecular Weight: 254.24
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: D424183
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    IUPAC Name
    1,8-dihydroxy-3-methylanthracene-9,10-dione
    SMILES
    CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
    InChIKey
    LQGUBLBATBMXHT-UHFFFAOYSA-N
    InChI
    1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
    Synonyms
    Chrysophanol|481-74-3|CHRYSOPHANIC ACID|3-Methylchrysazin|1,8-Dihydroxy-3-methylanthraquinone|Turkey rhubarb|1,8-dihy...
  12. 13(S)-Hydroperoxyoctadeca-9Z,11E-dienoic acid (13-HPODE)
    CAS: 33964-75-9 Formula: C18H32O4 Molecular Weight: 312.5
    ≥98% ~2mg/ml in Ethanol
    ◐ .Made to order · 8–12 wks Item #: H274925
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    Technical Identifiers
    IUPAC Name
    (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoic acid
    SMILES
    CCCCCC(C=CC=CCCCCCCCC(=O)O)OO
    InChIKey
    JDSRHVWSAMTSSN-IRQZEAMPSA-N
    InChI
    1S/C18H32O4/c1-2-3-11-14-17(22-21)15-12-9-7-5-4-6-8-10-13-16-18(19)20/h7,9,12,15,17,21H,2-6,8,10-11,13-14,16H2,1H3,(H,19,20)/b9-7-,15-12+/t17-/m0/s1
    Synonyms
    13(S)-Hydroperoxylinoleic acid | Q27098169 | 13S-hydroperoxy-9Z,11e-octadecadienoate | Linoleic acid, 13-hydroperoxy-...
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Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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