By Signaling Pathways - JAK/STAT Signaling Supplier | High Purity

Popular Products

Wish List Compare
AS1517499
CAS: 919486-40-1 Formula: C₂₀H₂₀ClN₅O₂ Molecular Weight: 397.86

≥97%

● In Stock — US warehouse, ships to EU* Item #: A414116
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-(benzylamino)-2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidine-5-carboxamide

SMILES

C1=CC=C(C=C1)CNC2=NC(=NC=C2C(=O)N)NCCC3=CC(=C(C=C3)O)Cl

InChIKey
OZRMEKAUZBKTTC-UHFFFAOYSA-N

InChI

1S/C20H20ClN5O2/c21-16-10-13(6-7-17(16)27)8-9-23-20-25-12-15(18(22)28)19(26-20)24-11-14-4-2-1-3-5-14/h1-7,10,12,27H,8-9,11H2,(H2,22,28)(H2,23,24,25,26show more

Synonyms
AS1517499, >=98% (HPLC) | 4-benzylamino-2-{[2-(3-chloro-4-hydroxyphenyl)ethyl]amino}pyrimidine-5-carboxamide | AKOS01...
Wish List Compare
AS2863619
CAS: 2241300-51-4 PubChem CID: 139600293 Formula: C₁₆H₁₄Cl₂N₈O Molecular Weight: 405.24

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: A422693
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-[1-(2-methyl-3H-benzimidazol-5-yl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine;dihydrochloride

SMILES

CC1=NC2=C(N1)C=C(C=C2)N3C4=C(C=NC=C4)N=C3C5=NON=C5N.Cl.Cl

InChIKey
LHUAALWRORLTCJ-UHFFFAOYSA-N

InChI

1S/C16H12N8O.2ClH/c1-8-19-10-3-2-9(6-11(10)20-8)24-13-4-5-18-7-12(13)21-16(24)14-15(17)23-25-22-14;;/h2-7H,1H3,(H2,17,23)(H,19,20);2*1H

Synonyms
1,2,5-Oxadiazol-3-amine,4-[1-(2-methyl-1H-benzimidazol-6-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-,hy...
Wish List Compare
ARRY-380
CAS: 937265-83-3 EC Number: 813-083-0 Formula: C₂₉H₂₇N₇O₄S Molecular Weight: 569.63

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: A426997
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine

SMILES

CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5

InChIKey
QVMNYGOVNWWFKF-UHFFFAOYSA-N

InChI

1S/C29H27N7O4S/c1-19-13-21(4-7-26(19)39-22-9-11-36-28(15-22)32-18-34-36)35-29-24-14-20(3-6-25(24)31-17-33-29)27-8-5-23(40-27)16-30-10-12-41(2,37)38/h3show more

Synonyms
BCP9000319 | NCGC00346672-01 | 4-quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-n-[3-methy...
Wish List Compare
AS2863619
CAS: 2241300-51-4 PubChem CID: 139600293 Formula: C₁₆H₁₄Cl₂N₈O Molecular Weight: 405.24

≥98%

● In Stock — US warehouse, ships to EU* Item #: A414258
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-[1-(2-methyl-3H-benzimidazol-5-yl)imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine;dihydrochloride

SMILES

CC1=NC2=C(N1)C=C(C=C2)N3C4=C(C=NC=C4)N=C3C5=NON=C5N.Cl.Cl

InChIKey
LHUAALWRORLTCJ-UHFFFAOYSA-N

InChI

1S/C16H12N8O.2ClH/c1-8-19-10-3-2-9(6-11(10)20-8)24-13-4-5-18-7-12(13)21-16(24)14-15(17)23-25-22-14;;/h2-7H,1H3,(H2,17,23)(H,19,20);2*1H

Synonyms
1,2,5-Oxadiazol-3-amine,4-[1-(2-methyl-1H-benzimidazol-6-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-,hy...
Wish List Compare
AZ5104, Inhibitor of epidermal growth factor receptor
CAS: 1421373-98-9 Formula: C₂₇H₃₁N₇O₂ Molecular Weight: 485.58

Moligand™ ? ≥97%

● In Stock — US warehouse, ships to EU* Item #: A413734
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide

SMILES

CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CNC4=CC=CC=C43)OC

InChIKey
IQNVEOMHJHBNHC-UHFFFAOYSA-N

InChI

1S/C27H31N7O2/c1-6-26(35)30-22-15-23(25(36-5)16-24(22)34(4)14-13-33(2)3)32-27-28-12-11-21(31-27)19-17-29-20-10-8-7-9-18(19)20/h6-12,15-17,29H,1,13-14Hshow more

Synonyms
2-Propenamide, N-(2-((2-(dimethylamino)ethyl)methylamino)-5-((4-(1H-indol-3-yl)-2-pyrimidinyl)amino)-4-methoxyphenyl)...
Wish List Compare
AZ5104, Inhibitor of epidermal growth factor receptor
CAS: 1421373-98-9 Formula: C₂₇H₃₁N₇O₂ Molecular Weight: 485.58

Moligand™ ? 10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: A421560
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide

SMILES

CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CNC4=CC=CC=C43)OC

InChIKey
IQNVEOMHJHBNHC-UHFFFAOYSA-N

InChI

1S/C27H31N7O2/c1-6-26(35)30-22-15-23(25(36-5)16-24(22)34(4)14-13-33(2)3)32-27-28-12-11-21(31-27)19-17-29-20-10-8-7-9-18(19)20/h6-12,15-17,29H,1,13-14Hshow more

Synonyms
2-Propenamide, N-(2-((2-(dimethylamino)ethyl)methylamino)-5-((4-(1H-indol-3-yl)-2-pyrimidinyl)amino)-4-methoxyphenyl)...
Wish List Compare
AT9283, Tyrosine-protein kinase JAK3 inhibitor
CAS: 896466-04-9 Formula: C₁₉H₂₃N₇O₂ Molecular Weight: 381.43

Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: A127488
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

1-cyclopropyl-3-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea

SMILES

C1CC1NC(=O)NC2=C(NN=C2)C3=NC4=C(N3)C=C(C=C4)CN5CCOCC5

InChIKey
LOLPPWBBNUVNQZ-UHFFFAOYSA-N

InChI

1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13H,2-3,5-8,11H2,(H,20,25)(H,22,23)show more

Synonyms
NSC799339 | NSC-799339 | AKOS016006006 | 1-cyclopropyl-3-[(3Z)-3-[5-(morpholin-4-ylmethyl)benzimidazol-2-ylidene]-1,2...
Wish List Compare
AZD-9291 mesylate, Epidermal growth factor receptor erbB1 inhibitor
CAS: 1421373-66-1 EC Number: 806-779-0 Formula: C₂₉H₃₇N₇O₅S Molecular Weight: 595.71

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: A421559
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid

SMILES

CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O

InChIKey
FUKSNUHSJBTCFJ-UHFFFAOYSA-N

InChI

1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-1show more

Synonyms
N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-pro...
Wish List Compare
AZD3759, Epidermal growth factor receptor erbB1 inhibitor
CAS: 1626387-80-1 Formula: C₂₂H₂₃ClFN₅O₃ Molecular Weight: 459.9

Moligand™ ? ≥99%

● In Stock — US warehouse, ships to EU* Item #: A413895
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2,4-dimethylpiperazine-1-carboxylate

SMILES

CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C

InChIKey
MXDSJQHFFDGFDK-CYBMUJFWSA-N

InChI

1S/C22H23ClFN5O3/c1-13-11-28(2)7-8-29(13)22(30)32-19-9-14-17(10-18(19)31-3)25-12-26-21(14)27-16-6-4-5-15(23)20(16)24/h4-6,9-10,12-13H,7-8,11H2,1-3H3,(show more

Synonyms
(R)-4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate | EX-A720 | zorife...
Wish List Compare
AZD3759, Epidermal growth factor receptor erbB1 inhibitor
CAS: 1626387-80-1 Formula: C₂₂H₂₃ClFN₅O₃ Molecular Weight: 459.9

Moligand™ ? 10mM in DMSO

◐ .Made to order · 8–12 wks Item #: A421980
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2,4-dimethylpiperazine-1-carboxylate

SMILES

CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C

InChIKey
MXDSJQHFFDGFDK-CYBMUJFWSA-N

InChI

1S/C22H23ClFN5O3/c1-13-11-28(2)7-8-29(13)22(30)32-19-9-14-17(10-18(19)31-3)25-12-26-21(14)27-16-6-4-5-15(23)20(16)24/h4-6,9-10,12-13H,7-8,11H2,1-3H3,(show more

Synonyms
(R)-4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate | EX-A720 | zorife...
Wish List Compare
AZD1208, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
CAS: 1204144-28-4 Formula: C₂₁H₂₁N₃O₂S Molecular Weight: 379.48

Moligand™ ? 10mM in DMSO

◐ .Made to order · 8–12 wks Item #: A420898
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

(5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione

SMILES

C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N

InChIKey
MCUJKPPARUPFJM-UWCCDQBKSA-N

InChI

1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18show more

Synonyms
AZD 1208 [WHO-DD] | Q27074698 | FT-0633869 | J-013789 | HY-15604 | S98NFM1378 | SW219766-1 | 1204144-28-4 | AZ-1208 |...
Wish List Compare
Abrocitinib (PF-04965842), Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2
CAS: 1622902-68-4 EC Number: 817-215-8 Formula: C₁₄H₂₁N₅O₂S Molecular Weight: 323.41

Moligand™ ? ≥97%

● In Stock — US warehouse, ships to EU* Item #: A414165
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide

SMILES

CCCS(=O)(=O)NC1CC(C1)N(C)C2=NC=NC3=C2C=CN3

InChIKey
IUEWXNHSKRWHDY-UHFFFAOYSA-N

InChI

1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)

Synonyms
Abrocitinib;N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide | N-(3-(Methyl(7H-...

🚚

Fast Shipping Same-day shipping on in-stock items

📋

Technical Details Quality & specification info on every product page

📦

Pack Size Options Multiple packaging sizes with pricing access from listing

🔬

R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?

Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.

Which JAK/STAT Signaling subcategory should I start with?

JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.

Which quality data should I check before ordering JAK/STAT Signaling?

Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search JAK/STAT Signaling by structure or CAS number?

Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.