JAK/STAT Signaling

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

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  1. Balsalazide Disodium Salt Dihydrate
    CAS: 150399-21-6 PubChem CID: 135414247 Formula: C17H13N3Na2O6·2H2O Molecular Weight: 437.32
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B421772
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    Technical Identifiers
    IUPAC Name
    disodium;3-[[4-[(3-carboxy-4-oxidophenyl)diazenyl]benzoyl]amino]propanoate;dihydrate
    SMILES
    C1=CC(=CC=C1C(=O)NCCC(=O)[O-])N=NC2=CC(=C(C=C2)[O-])C(=O)O.O.O.[Na+].[Na+]
    InChIKey
    XDCNKOBSQURQOZ-UHFFFAOYSA-L
    InChI
    1S/C17H15N3O6.2Na.2H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;show more
    Synonyms
    150399-21-6|Balsalazide Disodium|BALSALAZIDE DISODIUM DIHYDRATE|Balsalazide disodium salt dihydrate|Colazal|Colazide|...
  2. Balsalazide disodium, Cyclooxygenase inhibitor
    CAS: 213594-60-6 Formula: C17H13N3O6•Na Molecular Weight: 355.3022299
    ◐ .Made to order · 8–12 wks Item #: B356754
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    IUPAC Name
    disodium;3-[[4-[(3-carboxy-4-oxidophenyl)diazenyl]benzoyl]amino]propanoate
    SMILES
    C1=CC(=CC=C1C(=O)NCCC(=O)[O-])N=NC2=CC(=C(C=C2)[O-])C(=O)O.[Na+].[Na+]
    InChIKey
    CKMOQBVBEGCJGW-UHFFFAOYSA-L
    InChI
    1S/C17H15N3O6.2Na/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;/q;2*+1/show more
    Synonyms
    Sodium (E)-5-((4-((2-carboxylatoethyl)carbamoyl)phenyl)diazenyl)-2-hydroxybenzoate | FT-0658348 | NSC-760046 | LUMEFA...
  3. Baricitinib phosphate
    CAS: 1187595-84-1 EC Number: 112-584-5 Formula: C16H20N7O6PS Molecular Weight: 469.41
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B420825
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    IUPAC Name
    2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile;phosphoric acid
    SMILES
    CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
    InChIKey
    FBPOWTFFUBBKBB-UHFFFAOYSA-N
    InChI
    1S/C16H17N7O2S.H3O4P/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14;1-5(2,3)4/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20show more
    Synonyms
    AC-35322 | DTXSID30657980 | INCB-028050 phosphate | XIB47S8NNB | A892930 | Baricitinib phosphate salt | Baricitinib?P...
  4. Balsalazide
    CAS: 80573-04-2 EC Number: 617-116-8 Formula: C17H15N3O6 Molecular Weight: 357.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B426087
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    IUPAC Name
    5-[[4-(2-carboxyethylcarbamoyl)phenyl]diazenyl]-2-hydroxybenzoic acid
    SMILES
    C1=CC(=CC=C1C(=O)NCCC(=O)O)N=NC2=CC(=C(C=C2)O)C(=O)O
    InChIKey
    IPOKCKJONYRRHP-UHFFFAOYSA-N
    InChI
    1S/C17H15N3O6/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26)
    Synonyms
    BALSALAZIDE|80573-04-2|Balsalazido|Balsalazida|Balsalazidum|Balsalazidum [Latin]|Balsalazida [Spanish]|Balsalazido [S...
  5. Baricitinib phosphate
    CAS: 1187595-84-1 EC Number: 112-584-5 Formula: C16H20N7O6PS Molecular Weight: 469.41
    ● In Stock — US warehouse, ships to EU* Item #: B413326
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    Technical Identifiers
    IUPAC Name
    2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile;phosphoric acid
    SMILES
    CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
    InChIKey
    FBPOWTFFUBBKBB-UHFFFAOYSA-N
    InChI
    1S/C16H17N7O2S.H3O4P/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14;1-5(2,3)4/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20show more
    Synonyms
    AC-35322 | DTXSID30657980 | INCB-028050 phosphate | XIB47S8NNB | A892930 | Baricitinib phosphate salt | Baricitinib?P...
  6. Brevilin A
    CAS: 16503-32-5 EC Number: 111-884-3 PubChem CID: 12302076 Formula: C2OH26O5 Molecular Weight: 346.42
    ● In Stock — US warehouse, ships to EU* Item #: B413675
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    IUPAC Name
    [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] (Z)-2-methylbut-2-enoate
    SMILES
    CC=C(C)C(=O)OC1C2C(C(=O)OC2CC(C3C1(C(=O)C=C3)C)C)C
    InChIKey
    KUPPZVXLWANEJJ-UXPPPGSFSA-N
    InChI
    1S/C20H26O5/c1-6-10(2)18(22)25-17-16-12(4)19(23)24-14(16)9-11(3)13-7-8-15(21)20(13,17)5/h6-8,11-14,16-17H,9H2,1-5H3/b10-6-/t11-,12+,13+,14-,16-,17+,20show more
    Synonyms
    [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] (Z)-2-me...
  7. Butein
    CAS: 487-52-5 EC Number: 207-659-5 Formula: C15H12O5 Molecular Weight: 272.25
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B424228
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    IUPAC Name
    (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
    SMILES
    C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O
    InChIKey
    AYMYWHCQALZEGT-ORCRQEGFSA-N
    InChI
    1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+
    Synonyms
    (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one | HSCI1_000162 | Z2312273638 | (2E)-1-(2,4-Dihydro...
  8. C188-9, Inhibitor of signal transducer and activator of transcription 3
    CAS: 432001-19-9 EC Number: 836-653-0 Formula: C27H21NO5S Molecular Weight: 471.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C414081
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    IUPAC Name
    N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)naphthalen-1-yl]-4-methoxybenzenesulfonamide
    SMILES
    COC1=CC=C(C=C1)S(=O)(=O)NC2=CC(=C(C3=CC=CC=C32)O)C4=C(C=CC5=CC=CC=C54)O
    InChIKey
    QDCJDYWGYVPBDO-UHFFFAOYSA-N
    InChI
    1S/C27H21NO5S/c1-33-18-11-13-19(14-12-18)34(31,32)28-24-16-23(27(30)22-9-5-4-8-21(22)24)26-20-7-3-2-6-17(20)10-15-25(26)29/h2-16,28-30H,1H3
    Synonyms
    GTPL12268 | N-(4-hydroxy-3-(2-hydroxynaphthalen-1-yl)naphthalen-1-yl)-4-methoxybenzenesulfonamide | EX-A1961 | C 188-...
  9. CGP 52411
    CAS: 145915-58-8 Formula: C20H15N3O2 Molecular Weight: 329.35
    ◐ .Made to order · 8–12 wks Item #: C275419
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    IUPAC Name
    5,6-dianilinoisoindole-1,3-dione
    SMILES
    C1=CC=C(C=C1)NC2=C(C=C3C(=C2)C(=O)NC3=O)NC4=CC=CC=C4
    InChIKey
    AAALVYBICLMAMA-UHFFFAOYSA-N
    InChI
    1S/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)
    Synonyms
    4,5-dianilinophthalimide | CGP52411 | Cgp-52411 | DAPH, >=98% (HPLC), solid | DAPH-1 | Z13D008FZ2 | CGP52411;CGP-5241...
  10. CEP-33779, Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3
    CAS: 1257704-57-6 Formula: C24H26N6O2S Molecular Weight: 462.57
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C129474
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    IUPAC Name
    N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
    SMILES
    CN1CCN(CC1)C2=CC=CC(=C2)NC3=NN4C=CC=C(C4=N3)C5=CC=C(C=C5)S(=O)(=O)C
    InChIKey
    RFZKSQIFOZZIAQ-UHFFFAOYSA-N
    InChI
    1S/C24H26N6O2S/c1-28-13-15-29(16-14-28)20-6-3-5-19(17-20)25-24-26-23-22(7-4-12-30(23)27-24)18-8-10-21(11-9-18)33(2,31)32/h3-12,17H,13-16H2,1-2H3,(H,25show more
    Synonyms
    AS-16293 | SMR004703007 | N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyrid...
  11. CL-387785
    CAS: 194423-06-8 Formula: C18H13BrN4O Molecular Weight: 381.23
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: C422375
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    IUPAC Name
    N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-ynamide
    SMILES
    CC#CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
    InChIKey
    BTYYWOYVBXILOJ-UHFFFAOYSA-N
    InChI
    1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23)
    Synonyms
    DTXSID401236539 | N-[4-[(3-Bromophenyl)amino]quinazolin-6-yl]but-2-ynamide | MFCD02179194 | N-(4-((3-bromophenyl)amin...
  12. CL-387785
    CAS: 194423-06-8 Formula: C18H13BrN4O Molecular Weight: 381.23
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: C337834
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    Technical Identifiers
    IUPAC Name
    N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-ynamide
    SMILES
    CC#CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
    InChIKey
    BTYYWOYVBXILOJ-UHFFFAOYSA-N
    InChI
    1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23)
    Synonyms
    DTXSID401236539 | N-[4-[(3-Bromophenyl)amino]quinazolin-6-yl]but-2-ynamide | MFCD02179194 | N-(4-((3-bromophenyl)amin...
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Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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