By Signaling Pathways - JAK/STAT Signaling Supplier | High Purity

Popular Products

Wish List Compare
CYT387, Tyrosine-protein kinase JAK2 inhibitor
CAS: 1056634-68-4 EC Number: 894-079-6 Formula: C₂₃H₂₂N₆O₂ Molecular Weight: 414.47

Solid Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: C127224
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide

SMILES

C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N

InChIKey
ZVHNDZWQTBEVRY-UHFFFAOYSA-N

InChI

1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28)

Synonyms
C87 | DB11763 | KBioGR_000794 | N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide | NSC8...
Wish List Compare
Cancer cell stemness inhibitor (Napabucasin)
CAS: 83280-65-3 Formula: C₁₄H₈O₄ Molecular Weight: 240.21

Solid Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: C275982
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

2-acetylbenzo[f][1]benzofuran-4,9-dione

SMILES

CC(=O)C1=CC2=C(O1)C(=O)C3=CC=CC=C3C2=O

InChIKey
DPHUWDIXHNQOSY-UHFFFAOYSA-N

InChI

1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3

Synonyms
NAPABUCASIN [WHO-DD] | NSC788900 | (Indole-3-yl)acetonitrile | CCG-20461 | D10717 | EC 423-800-5 | AKOS027470201 | NA...
Wish List Compare
Canertinib (CI-1033), Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2
CAS: 267243-28-7 Formula: C₂₄H₂₅ClFN₅O₃ Molecular Weight: 485.94

Solid Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: C125447
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide

SMILES

C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4

InChIKey
OMZCMEYTWSXEPZ-UHFFFAOYSA-N

InChI

1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(Hshow more

Synonyms
PD-183805 | EC-000.2258 | BDBM4779 | N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acryl...
Wish List Compare
Canertinib (CI-1033), Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2
CAS: 267243-28-7 Formula: C₂₄H₂₅ClFN₅O₃ Molecular Weight: 485.94

Moligand™ ? 2mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: C422941
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide

SMILES

C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4

InChIKey
OMZCMEYTWSXEPZ-UHFFFAOYSA-N

InChI

1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(Hshow more

Synonyms
PD-183805 | EC-000.2258 | BDBM4779 | N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acryl...
Wish List Compare
Canertinib dihydrochloride, Receptor protein-tyrosine kinase erbB-4 inhibitor
CAS: 289499-45-2 EC Number: 663-691-3 PubChem CID: 156413 Formula: C₂₄H₂₅ClFN₅O₃·2HCl Molecular Weight: 558.86

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: C423017
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

SMILES

C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl.Cl

InChIKey
JZZFDCXSFTVOJY-UHFFFAOYSA-N

InChI

1S/C24H25ClFN5O3.2ClH/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16;;/h2,4-5,12-15H,1,3,6-show more

Synonyms
Q27280663 | A817177 | CI 1033 | EN300-19659633 | Canertinib(dihydrochloride) | PD 183805 | AKOS015924656 | Canertinib...
Wish List Compare
Cardamonin
CAS: 18956-16-6 Formula: C₁₆H₁₄O₄ Molecular Weight: 270.28

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: C422324
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

(E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

SMILES

COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O

InChIKey
NYSZJNUIVUBQMM-BQYQJAHWSA-N

InChI

1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+

Synonyms
(E)-Cardamomin; (E)-Alpinetin chalcone | 2',4'-dihydroxy-6'-methoxychalcone | Cardamonin | 2-Propen-1-one, 1-(2,4-dih...
Wish List Compare
Cerdulatinib, Tyrosine-protein kinase TYK2 inhibitor
CAS: 1198300-79-6 Formula: C₂₀H₂₇N₇O₃S Molecular Weight: 445.54

Solid Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: C413025
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide

SMILES

CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N

InChIKey
BGLPECHZZQDNCD-UHFFFAOYSA-N

InChI

1S/C20H27N7O3S/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21,28)(show more

Synonyms
HY-15999 | s3566 | AS-56368 | Q27075860 | Cerdulatinib | PRT2070 | PRT-2070 | Z1509507773 | RVT-502 | 4-(cyclopropyla...
Wish List Compare
Cerdulatinib, Tyrosine-protein kinase TYK2 inhibitor
CAS: 1198300-79-6 Formula: C₂₀H₂₇N₇O₃S Molecular Weight: 445.54

Moligand™ ? 10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: C420879
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide

SMILES

CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N

InChIKey
BGLPECHZZQDNCD-UHFFFAOYSA-N

InChI

1S/C20H27N7O3S/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21,28)(show more

Synonyms
HY-15999 | s3566 | AS-56368 | Q27075860 | Cerdulatinib | PRT2070 | PRT-2070 | Z1509507773 | RVT-502 | 4-(cyclopropyla...
Wish List Compare
Cerdulatinib (PRT062070) hydrochloride
CAS: 1369761-01-2 Formula: C₂₀H₂₈ClN₇O₃S Molecular Weight: 482

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: C421401
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide;hydrochloride

SMILES

CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N.Cl

InChIKey
IYULGYKOHUAYCG-UHFFFAOYSA-N

InChI

1S/C20H27N7O3S.ClH/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14;/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21show more

Synonyms
5-Pyrimidinecarboxamide, 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)-1-piperazinyl)phenyl)amino)-, hydrochloride (1...
Wish List Compare
Cerdulatinib hydrochloride
CAS: 1369761-01-2 Formula: C₂₀H₂₈ClN₇O₃S Molecular Weight: 482

≥98%

● In Stock — US warehouse, ships to EU* Item #: C413796
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide;hydrochloride

SMILES

CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N.Cl

InChIKey
IYULGYKOHUAYCG-UHFFFAOYSA-N

InChI

1S/C20H27N7O3S.ClH/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14;/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21show more

Synonyms
5-Pyrimidinecarboxamide, 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)-1-piperazinyl)phenyl)amino)-, hydrochloride (1...
Wish List Compare
Cetuximab (anti-EGFR)
CAS: 205923-56-4 Formula: Molecular Weight: 145543.35

Liquid Moligand™ ? ≥95% Protein concentration：5mg/ml

● In Stock — US warehouse, ships to EU* Item #: C302740
View Product
Pricing & Pack Sizes
Technical Identifiers

Associated targets
EGFR

Reactive species
Human
Isotype
Human IgG1
Host species
Human
Conjugation
Unconjugated
Wish List Compare
Cilengitide, Integrin alpha-V/beta-5 antagonist
CAS: 188968-51-6 Formula: C₂₇H₄₀N₈O₇ Molecular Weight: 588.66

Moligand™ ? 10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: C422313
View Product
Pricing & Pack Sizes
Technical Identifiers

IUPAC Name

2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acshow more

SMILES

CC(C)C1C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N

InChIKey
AMLYAMJWYAIXIA-VWNVYAMZSA-N

InChI

1S/C27H40N8O7/c1-15(2)22-25(41)33-17(10-7-11-30-27(28)29)23(39)31-14-20(36)32-18(13-21(37)38)24(40)34-19(26(42)35(22)3)12-16-8-5-4-6-9-16/h4-6,8-9,15,show more

Synonyms
NSC 707544 | DTXSID9044035 | c(RGDfMeV) | HY-16141 | 4EDF46E4GI | Cilengitide | Cilengitide [USAN:INN] | EMD121974 | ...

🚚

Fast Shipping Same-day shipping on in-stock items

📋

Technical Details Quality & specification info on every product page

📦

Pack Size Options Multiple packaging sizes with pricing access from listing

🔬

R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?

Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.

Which JAK/STAT Signaling subcategory should I start with?

JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.

Which quality data should I check before ordering JAK/STAT Signaling?

Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search JAK/STAT Signaling by structure or CAS number?

Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.