Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- GLPG0634 analogueCAS: 1206101-20-3 Formula: C23H18N6O2 Molecular Weight: 410.4310mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G420901View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
- SMILES
- C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5
- InChIKey
- RIJLVEAXPNLDTC-UHFFFAOYSA-N
- InChI
- 1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)
- Synonyms
- AMY3802 | AS-16295 | BCP08496 | N-(5-{4-[(1,1-dioxo-1lambda6-thiomorpholin-4-yl)methyl]phenyl}-[1,2,4]triazolo[1,5-a]...
- GYY 4137CAS: 106740-09-4 Formula: C11H16NO2PS2·C4H9NO Molecular Weight: 376.4710mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G420507View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (4-methoxyphenyl)-morpholin-4-yl-sulfanyl-sulfanylidene-λ5-phosphane;morpholine
- SMILES
- COC1=CC=C(C=C1)P(=S)(N2CCOCC2)S.C1COCCN1
- InChIKey
- YZMHNNLDUWRZFW-UHFFFAOYSA-N
- InChI
- 1S/C11H16NO2PS2.C4H9NO/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;1-3-6-4-2-5-1/h2-5H,6-9H2,1H3,(H,16,17);5H,1-4H2
- Synonyms
- BCP23715 | Morpholine (4-methoxyphenyl)(morpholino)phosphinodithioate | (4-Methoxyphenyl)morpholino-phosphinodithioic...
- Gefitinib hydrochloride saltCAS: 184475-55-6 Formula: C22H25Cl2FN4O3 Molecular Weight: 483.372mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G422258View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl
- InChIKey
- QUINXWLATMJDQF-UHFFFAOYSA-N
- InChI
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- Synonyms
- ZD1839 hydrochloride | ZD-1839 hydrochloride | 4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-[3-(4-morpholinyl)propoxy...
- Gefitinib hydrochloride saltCAS: 184475-55-6 Formula: C22H25Cl2FN4O3 Molecular Weight: 483.37● In Stock — US warehouse, ships to EU* Item #: G337638View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl
- InChIKey
- QUINXWLATMJDQF-UHFFFAOYSA-N
- InChI
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- Synonyms
- ZD1839 hydrochloride | ZD-1839 hydrochloride | 4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-[3-(4-morpholinyl)propoxy...
- Ginkgolic acid C17:1Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥98%● In Stock — US warehouse, ships to EU* Item #: G110234View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[(Z)-heptadec-10-enyl]-6-hydroxybenzoic acid
- SMILES
- CCCCCCC=CCCCCCCCCCC1=C(C(=CC=C1)O)C(=O)O
- InChIKey
- MBYNDKVOZOAOIS-FPLPWBNLSA-N
- InChI
- 1S/C24H38O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21-19-17-20-22(25)23(21)24(26)27/h7-8,17,19-20,25H,2-6,9-16,18H2,1H3,(H,26,27)/b8-7-
- Synonyms
- 2-(10-Heptadecenyl)-6-hydroxybenzoic acid | 2-[(10Z)-heptadec-10-en-1-yl]-6-hydroxybenzoic acid | GLXC-13680 | 6-(10'...
- Ginsenoside Rk1CAS: 494753-69-4 EC Number: 109-890-6 PubChem CID: 11499198 Formula: C42H70O12 Molecular Weight: 76710mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G424266View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC(=CCCC(=C)C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)C
- InChIKey
- KWDWBAISZWOAHD-MHOSXIPRSA-N
- InChI
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- Glycochenodeoxycholic acid, ABCB11CAS: 640-79-9 Formula: C26H43NO5 Molecular Weight: 449.62Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G425251View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
- InChIKey
- GHCZAUBVMUEKKP-GYPHWSFCSA-N
- InChI
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- Synonyms
- [(3alpha,7alpha-dihydroxy-24-oxo-5beta-cholan-24-yl)amino]acetic acid | 451ZNJ667Y | ST 24:1;O3;G | DTXSID301020165 |...
- Gusacitinib, Inhibitor of Janus kinase 2;Inhibitor of spleen associated tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G412595View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[1-[4-[4-(4-hydroxypiperidin-1-yl)anilino]-5-oxo-6H-pyrimido[4,5-d]pyridazin-2-yl]piperidin-4-yl]acetonitrile
- SMILES
- C1CN(CCC1CC#N)C2=NC3=C(C(=O)NN=C3)C(=N2)NC4=CC=C(C=C4)N5CCC(CC5)O
- InChIKey
- NLFLXLJXEIUQDL-UHFFFAOYSA-N
- InChI
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- Synonyms
- 1-(4-(4-(4-Hydroxy-piperidin-1-yl)-phenylamino)-5-oxo-5,6-dihydro-pyrimido(4,5-D)pyridazin-2-yl)-piperidin-4-YL-aceto...
- HG-14-10-04CAS: 1356962-34-9 Formula: C29H34ClN7O Molecular Weight: 532.0810mM in DMSO● In Stock — US warehouse, ships to EU* Item #: H421355View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-chloro-4-(1H-indol-3-yl)-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
- SMILES
- CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC
- InChIKey
- HRYNCLKDKCPYBF-UHFFFAOYSA-N
- InChI
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- Synonyms
- A906951 | AC-36124 | HY-15801 | HG141004 | HG-14-10-04 | 5-chloro-4-(1H-indol-3-yl)-N-[2-methoxy-4-[4-(4-methyl-1-pip...
- HG-14-10-04CAS: 1356962-34-9 Formula: C29H34ClN7O Molecular Weight: 532.08● In Stock — US warehouse, ships to EU* Item #: H413495View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-chloro-4-(1H-indol-3-yl)-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
- SMILES
- CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC
- InChIKey
- HRYNCLKDKCPYBF-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- A906951 | AC-36124 | HY-15801 | HG141004 | HG-14-10-04 | 5-chloro-4-(1H-indol-3-yl)-N-[2-methoxy-4-[4-(4-methyl-1-pip...
- HO-3867CAS: 1172133-28-6 Formula: C28H30F2N2O2 Molecular Weight: 464.55● In Stock — US warehouse, ships to EU* Item #: H413764View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one
- SMILES
- CC1(C=C(C(N1O)(C)C)CN2CC(=CC3=CC=C(C=C3)F)C(=O)C(=CC4=CC=C(C=C4)F)C2)C
- InChIKey
- PWZQFTQMMAIRRM-JFMUQQRKSA-N
- InChI
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- Synonyms
- 1-[(2,5-dihydro-1-hydroxy-2,2,5,5-tetramethyl-1H-pyrrol-3-yl)methyl]-3,5-bis[(4-fluorophenyl)methylene]-(3E,5E)-4-pip...
- HO-3867CAS: 1172133-28-6 Formula: C28H30F2N2O2 Molecular Weight: 464.5510mM in DMSO● In Stock — US warehouse, ships to EU* Item #: H420773View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one
- SMILES
- CC1(C=C(C(N1O)(C)C)CN2CC(=CC3=CC=C(C=C3)F)C(=O)C(=CC4=CC=C(C=C4)F)C2)C
- InChIKey
- PWZQFTQMMAIRRM-JFMUQQRKSA-N
- InChI
- show more
- Synonyms
- 1-[(2,5-dihydro-1-hydroxy-2,2,5,5-tetramethyl-1H-pyrrol-3-yl)methyl]-3,5-bis[(4-fluorophenyl)methylene]-(3E,5E)-4-pip...
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Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].