Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- TAS6417, Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: T414199View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(8S)-4-amino-6-methyl-5-quinolin-3-yl-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide
- SMILES
- CC1=CC(CN2C1=C(C3=C(N=CN=C32)N)C4=CC5=CC=CC=C5N=C4)NC(=O)C=C
- InChIKey
- MKCYPWYURWOKST-INIZCTEOSA-N
- InChI
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- Synonyms
- 1661854-97-2 | AS-79368 | D93895 | 2-Propenamide, N-((8S)-4-amino-8,9-dihydro-6-methyl-5-(3-quinolinyl)pyrimido(5,4-b...
- TAS0728● In Stock — US warehouse, ships to EU* Item #: T414209View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]pyrazolo[3,4-d]pyrimidine-3-carboxamide
- SMILES
- CC1=C(C=CC(=C1C)NC(=O)C2=NN(C3=NC=NC(=C23)N)C4CCCN(C4)C(=O)C=C)CC(=O)N(C)C
- InChIKey
- JCCIICHPRAAMGK-GOSISDBHSA-N
- InChI
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- Synonyms
- TPC 1071H-Pyrazolo[3,4-d]pyrimidine-3-carboxamide,4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-d...
- TCS PIM-1 110mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T424257View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1H-pyridine-3-carbonitrile
- SMILES
- C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N
- InChIKey
- SVSYJTYGPLVUOZ-UHFFFAOYSA-N
- InChI
- 1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23)
- Synonyms
- SC 204330;3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
- TG-8910mM in DMSO◐ .Made to order · 8–12 wks Item #: T426994View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-tert-butyl-3-[[5-methyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
- SMILES
- CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=CC(=C3)CN4CCOCC4
- InChIKey
- OOSKXASFJFSOBK-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 936091-56-4|TG-89|N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]ben...
- TG-89◐ .Made to order · 8–12 wks Item #: T412356View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-tert-butyl-3-[[5-methyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
- SMILES
- CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=CC(=C3)CN4CCOCC4
- InChIKey
- OOSKXASFJFSOBK-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BBL103534 | Benzenesulfonamide,N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidi...
- TP-3654CAS: 1361951-15-6 EC Number: 154-681-5 PubChem CID: 66598080 Formula: C22H25F3N4O Molecular Weight: 418.4610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T421375View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol
- SMILES
- CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O
- InChIKey
- XRNVABDYQLHODA-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- IndoFast Orange Lake OV 6014 | SB17245 | BCP30070 | A857573 | BDBM242374 | TP 3654 | SCHEMBL20794171 | CHEBI:180578 |...
- TP-3654CAS: 1361951-15-6 EC Number: 154-681-5 PubChem CID: 66598080 Formula: C22H25F3N4O Molecular Weight: 418.46● In Stock — US warehouse, ships to EU* Item #: T413627View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol
- SMILES
- CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O
- InChIKey
- XRNVABDYQLHODA-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- IndoFast Orange Lake OV 6014 | SB17245 | BCP30070 | A857573 | BDBM242374 | TP 3654 | SCHEMBL20794171 | CHEBI:180578 |...
- Tectochrysin10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T424459View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-hydroxy-7-methoxy-2-phenylchromen-4-one
- SMILES
- COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O
- InChIKey
- IRZVHDLBAYNPCT-UHFFFAOYSA-N
- InChI
- 1S/C16H12O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-9,17H,1H3
- Synonyms
- MLS001049041 | CCG-43780 | DTXSID40199962 | NCGC00017176-03 | SR-01000402578-1 | Methyl chrysin | NCGC00142540-01 | 5...
- TectochrysinSolid ≥98%● In Stock — US warehouse, ships to EU* Item #: T412871View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-hydroxy-7-methoxy-2-phenylchromen-4-one
- SMILES
- COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O
- InChIKey
- IRZVHDLBAYNPCT-UHFFFAOYSA-N
- InChI
- 1S/C16H12O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-9,17H,1H3
- Synonyms
- MLS001049041 | CCG-43780 | DTXSID40199962 | NCGC00017176-03 | SR-01000402578-1 | Methyl chrysin | NCGC00142540-01 | 5...
- Theliatinib (HMPL-309), Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 4;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of tyrosine kinase non receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%● In Stock — US warehouse, ships to EU* Item #: T414072View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3aR,6aR)-N-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxamide
- SMILES
- CN1CCC2C1CN(C2)C(=O)NC3=C(C=C4C(=C3)C(=NC=N4)NC5=CC=CC(=C5)C#C)OC
- InChIKey
- FSXCKIBROURMFT-VGSWGCGISA-N
- InChI
- show more
- Synonyms
- SCHEMBL247509 | AC-35865 | s8584 | AKOS032946520 | XILIERTINIB [WHO-DD] | 6ZZ3B7NZ0B | Pyrrolo(3,4-b)pyrrole-5(1H)-ca...
- Triacetyl resveratrolCAS: 42206-94-0 EC Number: 695-560-1 PubChem CID: 5962587 Formula: C20H18O6 Molecular Weight: 354.3510mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T423911View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [4-[(E)-2-(3,5-diacetyloxyphenyl)ethenyl]phenyl] acetate
- SMILES
- CC(=O)OC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)OC(=O)C)OC(=O)C
- InChIKey
- PDAYUJSOJIMKIS-SNAWJCMRSA-N
- InChI
- 1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+
- Synonyms
- 3,4',5-Triacetoxy-trans-stilbene | AC-34935 | NCGC00095675-02 | NSC793317 | NSC-793317 | [4-[(E)-2-(3,5-diacetyloxyph...
- Trastuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: T411999View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB2
- Short Overview
- Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- SMILES
- C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
- InChIKey
- FNXPTCITVCRFRK-UMMCILCDSA-N
- InChI
- 1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
- Synonyms
- 8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].