Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- FM-381CAS: 2226521-65-7 Formula: C24H24N6O2 Molecular Weight: 428.4910mM in DMSO● In Stock — US warehouse, ships to EU* Item #: F492016View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)furan-2-yl]-N,N-dimethylprop-2-enamide
- SMILES
- CN(C)C(=O)C(=CC1=CC=C(O1)C2=NC3=CN=C4C(=C3N2C5CCCCC5)C=CN4)C#N
- InChIKey
- GJMZWYLOARVASY-NTCAYCPXSA-N
- InChI
- show more
- Synonyms
- (E)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide
- Niclosamide Ethanolamine Salt● In Stock — US warehouse, ships to EU* Item #: C587196View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-aminoethanol;5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
- SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O.C(CO)N
- InChIKey
- XYCDHXSQODHSLG-UHFFFAOYSA-N
- InChI
- 1S/C13H8Cl2N2O4.C2H7NO/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15;3-1-2-4/h1-6,18H,(H,16,19);4H,1-3H2
- Synonyms
- Phenasal ethanolamine salt | SCHEMBL1871351 | Niclosamide-olamine | Ethanolamine salt of 5,2'-dichloro-4'-nitrosalicy...
- H 9 dihydrochloride● In Stock — US warehouse, ships to EU* Item #: H597562View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(2-aminoethyl)isoquinoline-5-sulfonamide;dihydrochloride
- SMILES
- C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl.Cl
- InChIKey
- HBLCYSFLYMHCBM-UHFFFAOYSA-N
- InChI
- 1S/C11H13N3O2S.2ClH/c12-5-7-14-17(15,16)11-3-1-2-9-8-13-6-4-10(9)11;;/h1-4,6,8,14H,5,7,12H2;2*1H
- Synonyms
- N-(2-Aminoethyl)-5-isoquinolinesulfonamidedihydrochloride
- CorylinCAS: 53947-92-5 Formula: C20H16O4 Molecular Weight: 320.34● In Stock — US warehouse, ships to EU* Item #: C418592View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one
- SMILES
- CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C
- InChIKey
- PWAACAMQKVIVPZ-UHFFFAOYSA-N
- InChI
- 1S/C20H16O4/c1-20(2)8-7-13-9-12(3-6-17(13)24-20)16-11-23-18-10-14(21)4-5-15(18)19(16)22/h3-11,21H,1-2H3
- Synonyms
- CCG-267706 | AKOS032948696 | MFCD20260784 | BDBM50349976 | SCHEMBL1096083 | 3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-h...
- CasticinCAS: 479-91-4 Formula: C19H18O8 Molecular Weight: 374.34Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) from Vitex trifolia◐ .Made to order · 8–12 wks Item #: C485965View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one
- SMILES
- COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O
- InChIKey
- PJQLSMYMOKWUJG-UHFFFAOYSA-N
- InChI
- 1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
- Synonyms
- DB11953 | s9288 | Casticin, primary pharmaceutical reference standard | Casticin | CASTICIN [USP-RS] | Casticin, anal...
- Cetuximab (anti-EGFR), Antibody of epidermal growth factor receptorCAS: 205923-56-4 Formula: Molecular Weight: 145543.35Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: C411992View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Short Overview
- Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference...
- Patritumab (anti-ERBB3), INHIBITOR of Receptor tyrosine-protein kinase erbB-3 inhibitorCAS: 1262787-83-6Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170705View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB3
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Rat
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Anti-ERBB3 / HER3 Reference Antibody (patritumab) | Patritumab | Human Anti-ERBB3 Recombinant Antibody | c erbB 3 ant...
- Necitumumab (anti-EGFR), Antibody of epidermal growth factor receptorCAS: 906805-06-9Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab169264View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Recombinant Necitumumab Antibody | Anti-ERBB1 / EGFR / HER1 Reference Antibody (necitumumab) | Necitumumab (anti-EGFR...
- Margetuximab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2CAS: 1350624-75-7Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170524View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB2
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
- WAY-339696CAS: 333419-97-9 Formula: C16H11BrN2O3 Molecular Weight: 359.17414● In Stock — US warehouse, ships to EU* Item #: W418133View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- OC1=C(C(=O)NC2=CC=CC(=C2)Br)C(=O)NC3=C1C=CC=C3
- Synonyms
- N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide
- AZD4604, Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2CAS: 2241039-81-4 EC Number: 882-805-4 PubChem CID: 135240395 Formula: C28H31F2N7O4S Molecular Weight: 599.65Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A607868View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2R)-N-[3-[5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
- SMILES
- CN1CCN(CC1)C(COC)C(=O)NC2=CC=CC3=C2NC=C3C4=NC(=NC=C4F)NC5=C(C(=CC=C5)S(=O)(=O)C)F
- InChIKey
- JNUZADQZHYFJGW-JOCHJYFZSA-N
- InChI
- show more
- Synonyms
- JAK1-IN-7 | Londamocitinib
- BI-4142, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 2682003-36-5 Formula: C28H27N9O2 Molecular Weight: 521.57Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: B608049View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(N1CCN(CC1)C2=NC=C3N=CN=C(C3=N2)NC4=CC=C(C(C)=C4)OC5=CC(N=CN6C)=C6C=C5)C=C
- Synonyms
- BI4142;compound 8;example L-1
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].