EGFR
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852 products
Popular Products
- CO-1686 (AVL-301), Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: C124905View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
- SMILES
- CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC
- InChIKey
- HUFOZJXAKZVRNJ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- NSC779405 | NSC-779405 | s7284 | NCGC00386293-08 | SB16488 | HUFOZJXAKZVRNJ-UHFFFAOYSA-N | CO1686 | CO-1686 | DB11907...
- CO-1686 (AVL-301), Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C421423View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
- SMILES
- CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC
- InChIKey
- HUFOZJXAKZVRNJ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- NSC779405 | NSC-779405 | s7284 | NCGC00386293-08 | SB16488 | HUFOZJXAKZVRNJ-UHFFFAOYSA-N | CO1686 | CO-1686 | DB11907...
- CUDC-101, Histone deacetylase inhibitorCAS: 1012054-59-9 Formula: C24H26N4O4 Molecular Weight: 434.49Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: C127191View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO
- InChIKey
- PLIVFNIUGLLCEK-UHFFFAOYSA-N
- InChI
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- Synonyms
- 7-((4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide | AS-16955 | FT-0665231 | UNII-1A7Y9M...
- Canertinib (CI-1033), Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 267243-28-7 Formula: C24H25ClFN5O3 Molecular Weight: 485.94Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: C125447View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
- SMILES
- C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
- InChIKey
- OMZCMEYTWSXEPZ-UHFFFAOYSA-N
- InChI
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- Synonyms
- PD-183805 | EC-000.2258 | BDBM4779 | N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acryl...
- Canertinib (CI-1033), Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 267243-28-7 Formula: C24H25ClFN5O3 Molecular Weight: 485.94Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C422941View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
- SMILES
- C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
- InChIKey
- OMZCMEYTWSXEPZ-UHFFFAOYSA-N
- InChI
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- Synonyms
- PD-183805 | EC-000.2258 | BDBM4779 | N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acryl...
- Canertinib dihydrochloride, Receptor protein-tyrosine kinase erbB-4 inhibitorCAS: 289499-45-2 EC Number: 663-691-3 PubChem CID: 156413 Formula: C24H25ClFN5O3·2HCl Molecular Weight: 558.8610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C423017View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride
- SMILES
- C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl.Cl
- InChIKey
- JZZFDCXSFTVOJY-UHFFFAOYSA-N
- InChI
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- Synonyms
- Q27280663 | A817177 | CI 1033 | EN300-19659633 | Canertinib(dihydrochloride) | PD 183805 | AKOS015924656 | Canertinib...
- Cetuximab (anti-EGFR)CAS: 205923-56-4 Formula: Molecular Weight: 145543.35Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% Protein concentration：5mg/ml● In Stock — US warehouse, ships to EU* Item #: C302740View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine, Inhibitor of epidermal growth factor receptorCAS: 171745-13-4 Formula: C18H18BrN3O2 Molecular Weight: 388.26Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%◐ .Made to order · 8–12 wks Item #: C336633View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine
- SMILES
- CCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OCC
- InChIKey
- YXOXHAUUTIOBDA-UHFFFAOYSA-N
- InChI
- 1S/C18H18BrN3O2/c1-3-23-16-9-14-15(10-17(16)24-4-2)20-11-21-18(14)22-13-7-5-6-12(19)8-13/h5-11H,3-4H2,1-2H3,(H,20,21,22)
- Synonyms
- 4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline | EGFR-IN-80 | N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine | Co...
- Cyasterone10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C422107View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1C(C(OC1=O)C)CC(C(C)(C2CCC3(C2(CCC4C3=CC(=O)C5C4(CC(C(C5)O)O)C)C)O)O)O
- InChIKey
- NEFYSBQJYCICOG-YSEUJXISSA-N
- InChI
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- Synonyms
- 5-beta-Stigmast-7-en-26-oic acid, 2-beta,3-beta,14,20,22,28-hexahydroxy-6-oxo-, gamma-lactone, (22R,24S,25S,28R)- | 5...
- Cyasterone● In Stock — US warehouse, ships to EU* Item #: C414397View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1C(C(OC1=O)C)CC(C(C)(C2CCC3(C2(CCC4C3=CC(=O)C5C4(CC(C(C5)O)O)C)C)O)O)O
- InChIKey
- NEFYSBQJYCICOG-YSEUJXISSA-N
- InChI
- show more
- Synonyms
- 5-beta-Stigmast-7-en-26-oic acid, 2-beta,3-beta,14,20,22,28-hexahydroxy-6-oxo-, gamma-lactone, (22R,24S,25S,28R)- | 5...
- DZD9008CAS: 2370013-49-1 Formula: C29H35ClFN7O3 Molecular Weight: 584.08● In Stock — US warehouse, ships to EU* Item #: D420007View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC(C)(C1=CC(=C(C=C1NC2=NC(=NC=C2)NC3=C(C=C(C(=C3)NC(=O)C=C)N4CCC(C4)N(C)C)OC)Cl)F)O
- InChIKey
- BTMKEDDEMKKSEF-KRWDZBQOSA-N
- InChI
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- Synonyms
- (S)-Sunvozertinib | 2-Propenamide, N-[5-[[4-[[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino]-2-pyrimidiny...
- EAI045, Allosteric modulator of epidermal growth factor receptorCAS: 1942114-09-1 Formula: C19H14FN3O3S Molecular Weight: 383.4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● In Stock — US warehouse, ships to EU* Item #: E413951View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
- SMILES
- C1C2=CC=CC=C2C(=O)N1C(C3=C(C=CC(=C3)F)O)C(=O)NC4=NC=CS4
- InChIKey
- YTUFHOKUFOQRDF-UHFFFAOYSA-N
- InChI
- 1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
- Synonyms
- 2H-Isoindole-2-acetamide,α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-N-2-thiazolyl- | (Z)-2-(5-flu...
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Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.