EGFR
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852 products
Popular Products
- PD089828● In Stock — US warehouse, ships to EU* Item #: P412948View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
- SMILES
- CC(C)(C)NC(=O)NC1=C(C=C2C=NC(=NC2=N1)N)C3=C(C=CC=C3Cl)Cl
- InChIKey
- RRWSNCZYJCOEFX-UHFFFAOYSA-N
- InChI
- 1S/C18H18Cl2N6O/c1-18(2,3)26-17(27)25-15-10(13-11(19)5-4-6-12(13)20)7-9-8-22-16(21)24-14(9)23-15/h4-8H,1-3H3,(H4,21,22,23,24,25,26,27)
- Pertuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2CAS: 380610-27-5 PubChem CID: 5484725Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: P412000View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CYP1A2 ERBB2 ADRB2
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Mouse, Rat
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
- SMILES
- CC1=C2CCCC2=C(C=C1)OCC(C(C)NC(C)C)O
- InChIKey
- VFIDUCMKNJIJTO-BBRMVZONSA-N
- InChI
- 1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16-/m0/s1
- Synonyms
- 2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, [R-(R*,S*)]- | Q27078025 | (2R,3S)-...
- Poziotinib (HM781-36B), Epidermal growth factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: P413748View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C
- InChIKey
- LPFWVDIFUFFKJU-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one | CCG-264748 | DB12...
- Pyrotinib dimaleate● In Stock — US warehouse, ships to EU* Item #: P414222View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CC5CCCN5C.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
- InChIKey
- KLHFGQSCVQPTIN-XUZAKNADSA-N
- InChI
- show more
- Synonyms
- (E)-N-[4-[[3-chloro-4-(2-pyridylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolyl]-3-[(2R)-1-methylpyrrolidin-2-yl]pr...
- RG-1302210mM in DMSO● In Stock — US warehouse, ships to EU* Item #: R421397View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile
- SMILES
- COC1=C(C=C(C=C1)C=C(C#N)C2=CN=CC=C2)OC
- InChIKey
- DBGZNJVTHYFQJI-ZSOIEALJSA-N
- InChI
- 1S/C16H14N2O2/c1-19-15-6-5-12(9-16(15)20-2)8-14(10-17)13-4-3-7-18-11-13/h3-9,11H,1-2H3/b14-8-
- SU-5402 (DMSO solution)CAS: 215543-92-3 Formula: C17H16N2O3 Molecular Weight: 296.32Liquid 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: S422593View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
- SMILES
- CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
- InChIKey
- JNDVEAXZWJIOKB-JYRVWZFOSA-N
- InChI
- 1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
- Synonyms
- HY-10407G | BCPP000060 | SCHEMBL177917 | SU 5402 | su5402 | SU-5402 | (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)meth...
- SU520410mM in DMSO● In Stock — US warehouse, ships to EU* Item #: S422280View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
- SMILES
- CCOC1=CC=CC=C1C=C2C3=CC=CC=C3NC2=O
- InChIKey
- MEZFKCPUSMBMAY-KAMYIIQDSA-N
- InChI
- 1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
- Synonyms
- 2H-Indol-2-one,3-[(2-ethoxyphenyl)methylene]-1,3-dihydro-
- SU5204≥98% EZ tautomeric mixture● In Stock — US warehouse, ships to EU* Item #: S412303View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
- SMILES
- CCOC1=CC=CC=C1C=C2C3=CC=CC=C3NC2=O
- InChIKey
- MEZFKCPUSMBMAY-KAMYIIQDSA-N
- InChI
- 1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
- Synonyms
- 2H-Indol-2-one,3-[(2-ethoxyphenyl)methylene]-1,3-dihydro-
- TAK-285, Epidermal growth factor receptor erbB1 inhibitor10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T426576View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-3-hydroxy-3-methylbutanamide
- SMILES
- CC(C)(CC(=O)NCCN1C=CC2=C1C(=NC=N2)NC3=CC(=C(C=C3)OC4=CC=CC(=C4)C(F)(F)F)Cl)O
- InChIKey
- ZYQXEVJIFYIBHZ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CHEBI:102166 | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-...
- TAS6417, Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T422062View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(8S)-4-amino-6-methyl-5-quinolin-3-yl-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide
- SMILES
- CC1=CC(CN2C1=C(C3=C(N=CN=C32)N)C4=CC5=CC=CC=C5N=C4)NC(=O)C=C
- InChIKey
- MKCYPWYURWOKST-INIZCTEOSA-N
- InChI
- show more
- Synonyms
- 1661854-97-2 | AS-79368 | D93895 | 2-Propenamide, N-((8S)-4-amino-8,9-dihydro-6-methyl-5-(3-quinolinyl)pyrimido(5,4-b...
- TAS6417, Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: T414199View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(8S)-4-amino-6-methyl-5-quinolin-3-yl-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide
- SMILES
- CC1=CC(CN2C1=C(C3=C(N=CN=C32)N)C4=CC5=CC=CC=C5N=C4)NC(=O)C=C
- InChIKey
- MKCYPWYURWOKST-INIZCTEOSA-N
- InChI
- show more
- Synonyms
- 1661854-97-2 | AS-79368 | D93895 | 2-Propenamide, N-((8S)-4-amino-8,9-dihydro-6-methyl-5-(3-quinolinyl)pyrimido(5,4-b...
- TAS0728● In Stock — US warehouse, ships to EU* Item #: T414209View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]pyrazolo[3,4-d]pyrimidine-3-carboxamide
- SMILES
- CC1=C(C=CC(=C1C)NC(=O)C2=NN(C3=NC=NC(=C23)N)C4CCCN(C4)C(=O)C=C)CC(=O)N(C)C
- InChIKey
- JCCIICHPRAAMGK-GOSISDBHSA-N
- InChI
- show more
- Synonyms
- TPC 1071H-Pyrazolo[3,4-d]pyrimidine-3-carboxamide,4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-d...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.