EGFR
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852 products
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- Myristicin10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: M425033View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-methoxy-6-prop-2-enyl-1,3-benzodioxole
- SMILES
- COC1=CC(=CC2=C1OCO2)CC=C
- InChIKey
- BNWJOHGLIBDBOB-UHFFFAOYSA-N
- InChI
- 1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3
- Synonyms
- CAS-607-91-0 | 4-Methoxy-6-[2-propenyl]-1,3-benzodioxole | HY-N2510 | NCGC00257726-01 | STK693140 | 04PD6CT78W | 1-Me...
- N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamineCAS: 916603-07-1 Formula: C17H16FN5 Molecular Weight: 309.3410mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N426919View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine
- SMILES
- C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN
- InChIKey
- UKOHFWNBTUJMMN-UHFFFAOYSA-N
- InChI
- 1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)
- Synonyms
- HY-111138 | N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine | N2-[4-(Aminomethyl)phenyl]-5-fluoro...
- NSC228155CAS: 113104-25-9 Formula: C11H6N4O4S Molecular Weight: 290.25● In Stock — US warehouse, ships to EU* Item #: N413968View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-nitro-4-(1-oxidopyridin-1-ium-2-yl)sulfanyl-2,1,3-benzoxadiazole
- SMILES
- C1=CC=[N+](C(=C1)SC2=CC=C(C3=NON=C23)[N+](=O)[O-])[O-]
- InChIKey
- ICCFXXDUYSPKOL-UHFFFAOYSA-N
- InChI
- 1S/C11H6N4O4S/c16-14-6-2-1-3-9(14)20-8-5-4-7(15(17)18)10-11(8)13-19-12-10/h1-6H
- Synonyms
- NSC228155 | 2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)pyridine 1-oxide
- NSC228155CAS: 113104-25-9 Formula: C11H6N4O4S Molecular Weight: 290.2510mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N420673View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-nitro-4-(1-oxidopyridin-1-ium-2-yl)sulfanyl-2,1,3-benzoxadiazole
- SMILES
- C1=CC=[N+](C(=C1)SC2=CC=C(C3=NON=C23)[N+](=O)[O-])[O-]
- InChIKey
- ICCFXXDUYSPKOL-UHFFFAOYSA-N
- InChI
- 1S/C11H6N4O4S/c16-14-6-2-1-3-9(14)20-8-5-4-7(15(17)18)10-11(8)13-19-12-10/h1-6H
- Synonyms
- NSC228155 | 2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)pyridine 1-oxide
- Naquotinib(ASP8273), Epidermal growth factor receptor erbB1 inhibitorCAS: 1448232-80-1 Formula: C30H42N8O3 Molecular Weight: 562.71Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%● In Stock — US warehouse, ships to EU* Item #: N414005View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-ethyl-3-[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxypyrazine-2-carboxamide
- SMILES
- CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC5CCN(C5)C(=O)C=C
- InChIKey
- QKDCLUARMDUUKN-XMMPIXPASA-N
- InChI
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- Synonyms
- D10958 | NAQUOTINIB [INN] | CCG-270060 | ASP8273 | ASP-8273 | VS-12093 | 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)pip...
- Naquotinib(ASP8273), Epidermal growth factor receptor erbB1 inhibitorCAS: 1448232-80-1 Formula: C30H42N8O3 Molecular Weight: 562.71Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N421653View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-ethyl-3-[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxypyrazine-2-carboxamide
- SMILES
- CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC5CCN(C5)C(=O)C=C
- InChIKey
- QKDCLUARMDUUKN-XMMPIXPASA-N
- InChI
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- Synonyms
- D10958 | NAQUOTINIB [INN] | CCG-270060 | ASP8273 | ASP-8273 | VS-12093 | 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)pip...
- Nazartinib (EGF816), Inhibitor of epidermal growth factor receptorCAS: 1508250-71-2 Formula: C26H31ClN6O2 Molecular Weight: 495.02Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: N413844View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide
- SMILES
- CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl
- InChIKey
- IOMMMLWIABWRKL-WUTDNEBXSA-N
- InChI
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- Synonyms
- N-(7-CHLORO-1-((3R)-1-((2E)-4-(DIMETHYLAMINO) BUT-2-ENOYL)AZEPAN-3-YL)-1HBENZIMIDAZOLOL-2-YL)-2-METHYLPYRIDINE-4-CARB...
- Nazartinib (EGF816), Inhibitor of epidermal growth factor receptorCAS: 1508250-71-2 Formula: C26H31ClN6O2 Molecular Weight: 495.02Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N421783View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide
- SMILES
- CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl
- InChIKey
- IOMMMLWIABWRKL-WUTDNEBXSA-N
- InChI
- show more
- Synonyms
- N-(7-CHLORO-1-((3R)-1-((2E)-4-(DIMETHYLAMINO) BUT-2-ENOYL)AZEPAN-3-YL)-1HBENZIMIDAZOLOL-2-YL)-2-METHYLPYRIDINE-4-CARB...
- Neratinib (HKI-272), Receptor protein-tyrosine kinase erbB-4 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N425586View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
- SMILES
- CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
- InChIKey
- JWNPDZNEKVCWMY-VQHVLOKHSA-N
- InChI
- show more
- Synonyms
- EC 244-343-6 | N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but...
- Olafertinib (RX-518)CAS: 1660963-42-7 Formula: C29H28F2N6O2 Molecular Weight: 530.57Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: O413541View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-[2-[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]quinazolin-8-yl]phenyl]prop-2-enamide
- SMILES
- C=CC(=O)NC1=CC=CC(=C1)C2=CC=CC3=CN=C(N=C32)NC4=C(C(=C(C=C4)N5CCN(CC5)CCO)F)F
- InChIKey
- IDRGFNPZDVBSSE-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- AKOS030632731 | olafertinib | N-[3-[2-[[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]amino]quinazolin-8-yl...
- Olmutinib, Epidermal growth factor receptor erbB1 inhibitorCAS: 1353550-13-6 Formula: C26H26N6O2S Molecular Weight: 486.59Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: O421342View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)SC=C4
- InChIKey
- FDMQDKQUTRLUBU-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- Example 1 [US20130116213] | DTXSID001319119 | FT-0615010 | SOTALOL HYDROCHLORIDE (USP-RS) | 4-{[4-({[(1R,2S)-2-Phenyl...
- PD15303510mM in DMSO◐ .Made to order · 8–12 wks Item #: P421820View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC
- InChIKey
- LSPANGZZENHZNJ-UHFFFAOYSA-N
- InChI
- 1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
- Synonyms
- BRD-K26603252-001-01-9 | EX-A1235 | NSC 669364 | AM808088 | GI 230329A | PD 153035 - CAS 153436-54-5 | s6546 | InChI=...
![N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine](https://www.aladdinsci.com/media/catalog/product/cache/6360e336b2a70951114dbd37294096ee/N/4/N426919.png)
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Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.