EGFR
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852 products
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- 1,2,3,4-Tetrahydrostaurosporine◐ .Made to order · 8–12 wks Item #: T276512View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC12C(C(CC(O1)N3C4=C(CCCC4)C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
- InChIKey
- KIZWKTROWIIMNN-FYTWVXJKSA-N
- InChI
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- Synonyms
- 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE | AFN 941 | Q27454934 | (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1...
- 1,8-Dihydroxy-3-methylanthraquinoneLiquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: D424183View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1,8-dihydroxy-3-methylanthracene-9,10-dione
- SMILES
- CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
- InChIKey
- LQGUBLBATBMXHT-UHFFFAOYSA-N
- InChI
- 1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
- Synonyms
- Chrysophanol|481-74-3|CHRYSOPHANIC ACID|3-Methylchrysazin|1,8-Dihydroxy-3-methylanthraquinone|Turkey rhubarb|1,8-dihy...
- 13(S)-Hydroperoxyoctadeca-9Z,11E-dienoic acid (13-HPODE)CAS: 33964-75-9 Formula: C18H32O4 Molecular Weight: 312.5≥98% ~2mg/ml in Ethanol◐ .Made to order · 8–12 wks Item #: H274925View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoic acid
- SMILES
- CCCCCC(C=CC=CCCCCCCCC(=O)O)OO
- InChIKey
- JDSRHVWSAMTSSN-IRQZEAMPSA-N
- InChI
- 1S/C18H32O4/c1-2-3-11-14-17(22-21)15-12-9-7-5-4-6-8-10-13-16-18(19)20/h7,9,12,15,17,21H,2-6,8,10-11,13-14,16H2,1H3,(H,19,20)/b9-7-,15-12+/t17-/m0/s1
- Synonyms
- 13(S)-Hydroperoxylinoleic acid | Q27098169 | 13S-hydroperoxy-9Z,11e-octadecadienoate | Linoleic acid, 13-hydroperoxy-...
- 3-(4-Isopropylbenzylidenyl)indolin-2-one(SU-4313)CAS: 186611-55-2 Formula: C18H17NO Molecular Weight: 263.33Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: I337822View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3E)-3-[(4-propan-2-ylphenyl)methylidene]-1H-indol-2-one
- SMILES
- CC(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O
- InChIKey
- IRQQWCZKCUQNSO-LFIBNONCSA-N
- InChI
- 1S/C18H17NO/c1-12(2)14-9-7-13(8-10-14)11-16-15-5-3-4-6-17(15)19-18(16)20/h3-12H,1-2H3,(H,19,20)/b16-11+
- Synonyms
- SU-4313 | SU 4313 | 3-(4-Isopropylbenzylidene)indolin-2-one
- AG 1406CAS: 71308-34-4 Formula: C16H18N2O Molecular Weight: 254.33● In Stock — US warehouse, ships to EU* Item #: A412268View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile
- SMILES
- CC(C)C1=CC(=CC(=C1O)C(C)C)C=C(C#N)C#N
- InChIKey
- JSDJFOADLLJFQX-UHFFFAOYSA-N
- InChI
- 1S/C16H18N2O/c1-10(2)14-6-12(5-13(8-17)9-18)7-15(11(3)4)16(14)19/h5-7,10-11,19H,1-4H3
- Synonyms
- 71308-34-4|Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-|AG 1406|AG1406|2-[[4-hydroxy-3,5-di...
- AG 43CAS: 5553-97-9 Formula: C10H8N2O Molecular Weight: 172.18● In Stock — US warehouse, ships to EU* Item #: A336632View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[(4-hydroxyphenyl)methyl]propanedinitrile
- SMILES
- C1=CC(=CC=C1CC(C#N)C#N)O
- InChIKey
- PDRLQWJJFLVIRC-UHFFFAOYSA-N
- InChI
- 1S/C10H8N2O/c11-6-9(7-12)5-8-1-3-10(13)4-2-8/h1-4,9,13H,5H2
- Synonyms
- Tyrphostin A63 | 2-(4-hydroxybenzyl)malononitrile | 2-[(4-hydroxyphenyl)methyl]propanedinitrile
- AG 555 (Tyrphostin B46)CAS: 133550-34-2 Formula: C19H18N2O3 Molecular Weight: 322.3610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A421271View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide
- SMILES
- C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
- InChIKey
- GSQOBTOAOGXIFL-LFIBNONCSA-N
- InChI
- 1S/C19H18N2O3/c20-13-16(11-15-8-9-17(22)18(23)12-15)19(24)21-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,22-23H,4,7,10H2,(H,21,24)/b16-11+
- Synonyms
- NCGC00016028-05 | Tyrphostin deriv. 46 | J-006402 | 2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-...
- AG 9910mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A420966View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
- SMILES
- C1=CC(=C(C=C1C=C(C#N)C(=O)N)O)O
- InChIKey
- USOXQZNJFMKTKJ-XVNBXDOJSA-N
- InChI
- 1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+
- Synonyms
- Tyrphostin A46|AG 99|122520-85-8|Tyrphostin 46|118409-59-9|Tyrphostin AG 99|AG-99|(E)-2-cyano-3-(3,4-dihydroxyphenyl)...
- AG-1557CAS: 189290-58-2 Formula: C16H14IN3O2 Molecular Weight: 407.21● In Stock — US warehouse, ships to EU* Item #: A412206View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)I)OC
- InChIKey
- FGCLAQLIXMAIHT-UHFFFAOYSA-N
- InChI
- 1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
- Synonyms
- 4-Quinazolinamine, N-(3-iodophenyl)-6,7-dimethoxy- | MFCD28902185 | N-(3-Iodophenyl)-6,7-dimethoxy-4-quinazolinamine ...
- AG-1557CAS: 189290-58-2 Formula: C16H14IN3O2 Molecular Weight: 407.2110mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A422322View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)I)OC
- InChIKey
- FGCLAQLIXMAIHT-UHFFFAOYSA-N
- InChI
- 1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
- Synonyms
- 4-Quinazolinamine, N-(3-iodophenyl)-6,7-dimethoxy- | MFCD28902185 | N-(3-Iodophenyl)-6,7-dimethoxy-4-quinazolinamine ...
- ARRY-38010mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A426997View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine
- SMILES
- CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5
- InChIKey
- QVMNYGOVNWWFKF-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BCP9000319 | NCGC00346672-01 | 4-quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-n-[3-methy...
- AZ5104, Inhibitor of epidermal growth factor receptorCAS: 1421373-98-9 Formula: C27H31N7O2 Molecular Weight: 485.58Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: A413734View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide
- SMILES
- CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CNC4=CC=CC=C43)OC
- InChIKey
- IQNVEOMHJHBNHC-UHFFFAOYSA-N
- InChI
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- Synonyms
- 2-Propenamide, N-(2-((2-(dimethylamino)ethyl)methylamino)-5-((4-(1H-indol-3-yl)-2-pyrimidinyl)amino)-4-methoxyphenyl)...
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Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.