≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
AG 43 is an inactive tyrphostin analogue that can be used a negative control parameter for other tyrphostins, mainly Tyrphostin 47 (RG-50864, AG-213) , for epidermal growth factor receptor tyrosine kinase activity or protein tyrosine kinase studies. AG 43 is an inhibitor of EGFR (epidermal growth factor receptor).
| pKa | pKₐ: 9.46 (Predicted) |
|---|
| Pubchem Sid | 504750920 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750920 |
| Canonical Smiles | C1=CC(=CC=C1CC(C#N)C#N)O |
| IUPAC Name | 2-[(4-hydroxyphenyl)methyl]propanedinitrile |
| InChIKey | PDRLQWJJFLVIRC-UHFFFAOYSA-N |
| INCHI | 1S/C10H8N2O/c11-6-9(7-12)5-8-1-3-10(13)4-2-8/h1-4,9,13H,5H2 |
| Isomeric SMILES | C1=CC(=CC=C1CC(C#N)C#N)O |
| WGK Germany | 3 |
| Molecular Weight | 172.18 |
| Reaxy-Rn | 2968329 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2968329&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Phenols |
| Subclass | 1-hydroxy-2-unsubstituted benzenoids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 1-hydroxy-2-unsubstituted benzenoids |
| Alternative Parents | Benzene and substituted derivatives Nitriles Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Nitrile - Carbonitrile - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as 1-hydroxy-2-unsubstituted benzenoids. These are phenols that a unsubstituted at the 2-position. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2407255 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407256 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407257 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407258 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407259 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407260 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407261 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| K2407262 | Certificate of Analysis | Oct 30, 2024 | A336632 |
| Solubility | Soluble in DMSO (10 mg/ml), and ethanol (25 mg/ml). Insoluble in water. |
|---|---|
| Refractive Index | n20D1.58 (Predicted) |
| Boil Point(°C) | 421.00° C at 760 mmHg (Predicted) |
| Melt Point(°C) | 115.33° C (Predicted) |
| Molecular Weight | 172.180 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 172.064 Da |
| Monoisotopic Mass | 172.064 Da |
| Topological Polar Surface Area | 67.800 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 233.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
