GRADE & PURITYBioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.High Performance?High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short.EnzymoPure™?EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance.≥95%(SDS-PAGE)Pre-lyophilization Protein Concentration
ActiBioPure™, Bioactive, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), Pre-lyophilization Protein Concentration ActiBioPure™,Bioactive,High Performance,EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
This enzyme degrades elastin, collagen, and proteoglycan and has been implicated in the development of pulmonary emphesema and rheumatoid arthritis. Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
Specifications
Product Name
Elastase from Human Neutrophil, CAS No.9004-06-2
Synonyms
Bone marrow serine protease | EC 3.4.21 | EC 3.4.21.37 | ELA2 | granulocyte-derived elastase | ELANE | elastase 2 | neutrophil | elastase | neutrophil expressed | Elastase-2 | GE | HNE | Human leukocyte elastase | Leukocyte Elastase | Medullasin | NE | Ne
Grade
ActiBioPure™, Bioactive, High Performance, EnzymoPure™
Specifications & Purity
ActiBioPure™, Bioactive, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), Pre-lyophilization Protein Concentration
Biochemical and Physiological Mechanisms
Serine protease that modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Promotes cleavage of GSDMB, thereby inhibiting pyroptosis. Promotes blood coagulation. Throug
After centrifugation, we suggest addition of 52.1 uL of 50 mM Na Acetate, pH 5.5, with 150 mMNaCl to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ long term (>1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
Unit definition
One unit is defined as the amount of enzyme which hydrolyzes one umole of Meo-suc-ala-ala-pro-val-pNA per minute at 25oC in 100 mMTris-HCl, pH 7.5, with 500 mMNaCl.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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