GPCRs, integrins, and receptor tyrosine kinases regulate actin polymerization, contraction, and adhesion turnover through Rho family small GTPases, thereby controlling cell migration, morphology, and tissue function.
Topic
cytoskeleton
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
4 resources · protocols, FAQs & articles
Cell membrane microdomains are jointly organized by specific lipids, scaffold proteins, and the cytoskeleton. They can restrict membrane protein diffusion and regulate ion channels, transporters, receptor signaling, and vesicular trafficking. Abnormalities in membrane microdomain composition ...
The cytoskeleton is a dynamic fibrous network composed of microfilaments, microtubules, and intermediate filaments, mainly consisting of actin, tubulin, and different types of intermediate filament proteins. The cytoskeleton not only maintains cell morphology, cell polarity, and intracellular ...
Microfilaments are mainly formed by the polymerization of actin and are an important component of the cytoskeleton. They participate in the maintenance of cell morphology, adhesion and migration, cytokinesis, endocytic transport, stress fiber formation, and the establishment of cell polarity.
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Techniques often explored alongside immunological experiments.