1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Nitrogen-containing S(VI) functional groups such as sulfoximines and sulfonimidamides have attracted sustained interest in medicinal chemistry and organic synthesis in recent years. Compared with conventional sulfones and sulfonamides, these structures introduce an additional nitrogen ...
Activins and inhibins both belong to the TGF-β superfamily and are formed by different combinations of inhibin subunits, but they exert opposing effects on the regulation of pituitary follicle-stimulating hormone (FSH). Activins promote FSH synthesis and secretion, whereas inhibins restrict ...
In gas–liquid packed columns used in gas chromatography (Gas Chromatography, GC), the solid support is a solid material used to retain and disperse the stationary liquid. After a sample enters the chromatographic column, it repeatedly partitions between the carrier gas and the stationary ...
Aging involves persistent dysregulation of nutrient sensing, energy metabolism, protein homeostasis, and chronic inflammation. IIS, mTOR, AMPK, NF-κB, and Sirtuins are interconnected through nodes including AKT, FOXO, ULK1, and NAD⁺ and jointly regulate cell growth, autophagy, stress ...
When evaluating niacinamide products, attention is often focused first on the concentration used, while several conditions that come before concentration are easily overlooked: the molecular state in which niacinamide exists, whether it can remain stable in the formulation, whether it can enter ...
Chemokines are a class of small secreted proteins that regulate directional cell migration. They primarily establish spatial signals through chemokine receptors, cell-surface glycosaminoglycans, and cell-adhesion systems, thereby guiding neutrophils, monocytes, T cells, NK cells, and other cells ...
Marine natural products (MNPs) are bioactive metabolites produced by marine microorganisms, algae, invertebrates, and other marine organisms. They are characterized by novel molecular scaffolds, complex stereochemical structures, a high abundance of halogenated compounds, and diverse biological ...
Disulfidptosis is a form of regulated cell death driven by abnormal intracellular disulfide accumulation and collapse of the actin cytoskeleton. It typically occurs in cells with high SLC7A11 expression under conditions of restricted glucose utilization and insufficient NADPH supply, reflecting ...
Ganoderma lucidum extract used in skincare products is not a structurally defined single compound, but rather a mixture composed of polysaccharides, triterpenoids, sterols, proteins, glycoproteins, and other accompanying constituents. The specific Ganoderma species, the part used, the ...
