L-Serine - Moligand™, 10mM in Water , CAS No.56-45-1

Name: L-Serine - Moligand™, 10mM in Water , CAS No.56-45-1
SKU: L424779
Availability: InStock

CAS: 56-45-1 Cat. No.: L424779 Formula: HOCH₂CH(NH₂)CO₂H Molecular Weight: 105.09 Beilstein Registry Number: 1721404 EC Number: 200-274-3

374 Citations COA

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L-Serine - Moligand™, 10mM in Water CAS No(56-45-1) L424779 by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? 10mM in Water

Synonyms

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product Solution Calculators Reviews

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Why this grade

Moligand™, 10mM in Water Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 374 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.

Specifications

Synonyms

Specifications & Purity

Moligand™, 10mM in Water

Biochemical and Physiological Mechanisms

Non-essential amino acid . Used as a precursor to several amino acids, including glycine, cysteine and other metabolites such as sphingolipids and folate. Also used in bio-synthesis of purines and pyrimidines.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

Pubchem Sid

528765143

Canonical Smiles

C(C(C(=O)O)N)O

IUPAC Name

(2S)-2-amino-3-hydroxypropanoic acid

InChIKey

MTCFGRXMJLQNBG-REOHCLBHSA-N

INCHI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

Isomeric SMILES

C([C@@H](C(=O)O)N)O

WGK Germany

RTECS

VT8100000

Molecular Weight

105.09

Beilstein

1721404

Reaxy-Rn

1721402

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721402&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Serine and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent	Serine and derivatives
Alternative Parents	L-alpha-amino acids Beta hydroxy acids and derivatives Amino acids Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Serine or derivatives - Alpha-amino acid - L-alpha-amino acid - Beta-hydroxy acid - Hydroxy acid - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Alcohol - Primary amine - Primary alcohol - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Primary aliphatic amine - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as serine and derivatives. These are compounds containing serine or a derivative thereof resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors	Common amino acids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

GPRC6A Tchem G-protein coupled receptor family C group 6 member A (1 Activities)

Discover Target: GPRC6A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

F2 Tclin Thrombin (11687 Activities)

Discover Target: F2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

Discover Target: HTR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)

Discover Target: GABRA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

Discover Target: DRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

Discover Target: SLC6A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

Discover Target: ADRA1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

Discover Target: DRD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

Discover Target: PDE3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

Discover Target: HTR2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

Discover Target: TBXA2R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

Discover Target: PDE4A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

Discover Target: ADORA3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH3 Tclin Histamine H3 receptor (10389 Activities)

Discover Target: HRH3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

Discover Target: KDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC1A4 Tbio Neutral amino acid transporter A (18 Activities)

Discover Target: SLC1A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)

Discover Target: SLC36A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC1A5 Tchem Neutral amino acid transporter B(0) (65 Activities)

Discover Target: SLC1A5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)

Discover Target: Pkm

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ggt1 Gamma-glutamyltranspeptidase 1 (36 Activities)

Discover Target: Ggt1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCHE Cholinesterase (8742 Activities)

Discover Target: BCHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Grin1 Glutamate NMDA receptor (6467 Activities)

Discover Target: Grin1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc16a10 Monocarboxylate transporter 10 (73 Activities)

Discover Target: Slc16a10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Gamma-glutamyltranspeptidase (21 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAP1 General amino-acid permease GAP1 (481 Activities)

Discover Target: GAP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc1a5 Amino acid transporter (271 Activities)

Discover Target: Slc1a5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Date	Item
K2223006	Certificate of Analysis	Aug 01, 2026	L424779

Chemical and Physical Properties

Specific Rotation[α]	15° (C=10,HCl(1+5))
Melt Point(°C)	228°C(dec.)(lit.)
Molecular Weight	105.090 g/mol
XLogP3	-3.100
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	105.043 Da
Monoisotopic Mass	105.043 Da
Topological Polar Surface Area	83.600 Å²
Heavy Atom Count	7
Formal Charge	0
Complexity	72.600
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Documents & Articles

β-Acyloxy Alkenyl Amides (AAAs): A New Approach to Amide Bond and Peptide Bond Construction Worth Attention

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

AAAs β-Acyloxy Alkenyl Amides

Silicon Reagent-Assisted Peptide Synthesis: Research Progress and Methodological Value of Peptide Bond Formation from Unprotected Substrates

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Peptide synthesis

From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

HPLC Peptide synthesis coupling reagent Analytical Instrument

Functional Systems of Plasma Proteins in Metal Transport, Inflammatory Responses, and Tissue Injury

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Albumin Metal Transferrin Haptoglobin Plasma Proteins Transport Ceruloplasmin Hemopexin Inflammatory Response Tissue Injury Oxidative Stress

Progress in Research on the S-Adenosylmethionine Cycle and Regulatory Mechanisms of Methyltransfer Reactions

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

methyl donor one-carbon metabolism Methionine Cycle Epigenetic Regulation S-Adenosylmethionine SAM cycle Methyl-transfer reactions S-adenosylhomocysteine

Methods and Applications for the Determination of Amino Acid Content and Composition

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Amino acids Mass spectrometry High-performance liquid chromatography Derivatization free amino acids total amino acids amino acid composition ninhydrin

Experimental Selection of Burgess Reagent: A Decision Framework for Alcohol Dehydration, Primary Amide/Aldoxime Dehydration, and Oxazoline/Thiazoline Cyclization

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Burgess reagent Dehydration reagent

Porous Graphitic Carbon (PGC) Chromatography Columns: Creating New Selectivity for Challenging Separations through Molecular Shape and the π-Electron Cloud on the Graphitic Surface

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

High-performance liquid chromatography Porous Graphitic Carbon

Performance Sources and Formulation Applications of Enzyme-Based Ingredients in Daily Chemical Products: Fermentation Transformation, Enzymatic Reactions, and Application Principles

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Enzyme Enzymes

Formation and Control of Carboxyl- and Hydroxyl-Related Impurities in Peptide Synthesis — Using Asp/Glu and Ser/Thr Residue Side Reactions as Examples

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Peptide synthesis Functional Group Carboxyl group

Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Hydrolyzed Pearl

Moisturizing Mechanism of Polyglutamic Acid: From the γ-Glutamyl Structure to Hydration Networks and Surface Film-Forming Behavior

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

cosmetics Polyglutamic Acid

Mechanisms by Which Fructan-Rich Ophiopogon japonicus Tuberous Root Extract Supports Skin Moisturization and Barrier Function

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Ophiopogon japonicus Root Extract Ophiopogon polysaccharides

Multilevel Moisturizing Mechanisms of Sodium Hyaluronate and Its Derivatives: Molecular Weight Modulation, Crosslinking, Acetylation, and Major Sites of Action

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Hyaluronic acid Sodium Hyaluronate HA

How Palmitoyl Pentapeptide-4 Acts on the Skin: From the KTTKS Sequence and Skin Delivery to Collagen Matrix Responses

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Synthetic lipopeptides

The Combination Logic of Palmitoyl Tripeptide-1 and Palmitoyl Pentapeptide-4: Skin Delivery, Matrix Signaling, and Regulation of Collagen Homeostasis

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

peptide palmitoyl chain

Citations of This Product

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Reviews

📚 Citations by Application

Other applications188

Extraction & workup solvent104

Organic synthesis — reaction medium176

Drug / compound screening87

Spectroscopy sample preparation99

Chromatography (HPLC / GC / TLC)31

Electrochemistry & battery electrolyte17

Cross-coupling reactions2

Crystallization & recrystallization2

Industrial & non-pharma application8

Nanoparticle / material biocompatibility8

Cytotoxicity screening9

Controlled-release & nanoparticle carrier6

Polymer synthesis & polymerization9

Cancer cell line characterization3

Cell viability10

IC50 determination2

Cell proliferation2

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L-Serine - Moligand™, 10mM in Water , CAS No.56-45-1

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

📚 Citations by Application

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